Predictive performance of the new race-free Chronic Kidney Disease Epidemiology Collaboration equations for kidney outcome in Korean patients with chronic kidney disease
DC Field | Value | Language |
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dc.contributor.author | Kim, Hyoungnae | - |
dc.contributor.author | Hyun, Young Youl | - |
dc.contributor.author | Yun, Hae-Ryong | - |
dc.contributor.author | Joo, Young Su | - |
dc.contributor.author | Kim, Yaeni | - |
dc.contributor.author | Jung, Ji Yong | - |
dc.contributor.author | Jeong, Jong Cheol | - |
dc.contributor.author | Kim, Jayoun | - |
dc.contributor.author | Park, Jung Tak | - |
dc.contributor.author | Yoo, Tae-Hyun | - |
dc.contributor.author | Kang, Shin-Wook | - |
dc.contributor.author | Oh, Kook-Hwan | - |
dc.contributor.author | Han, Seung Hyeok | - |
dc.date.accessioned | 2024-03-19T12:30:31Z | - |
dc.date.available | 2024-03-19T12:30:31Z | - |
dc.date.issued | 2023-07 | - |
dc.identifier.issn | 2211-9132 | - |
dc.identifier.issn | 2211-9140 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/90751 | - |
dc.description.abstract | Background: The new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations without a race coefficient have gained recognition across the United States. We aimed to test whether these new equations performed well in Korean patients with chronic kidney disease (CKD). Methods: This study included 2,149 patients with CKD G1-G5 without kidney replacement therapy from the Korean Cohort Study for Outcome in Patients with CKD (KNOW-CKD). The estimated glomerular filtration rate (eGFR) was calculated using the new CKD-EPI equations with serum creatinine and cystatin C. The primary outcome was 5-year risk of kidney failure with replacement therapy (KFRT). Results: When we adopted the new creatinine equation [eGFRcr (NEW)], 81 patients (23.1%) with CKD G3a based on the current cre-atinine equation (eGFRcr) were reclassified as CKD G2. Accordingly, the number of patients with eGFR of <60 mL/min/1.73 m2 de-creased from 1,393 (64.8%) to 1,312 (61.1%). The time-dependent area under the receiver operating characteristic curve for 5-year KFRT risk was comparable between the eGFRcr (NEW) (0.941; 95% confidence interval [CI], 0.922-0.960) and eGFRcr (0.941; 95% CI, 0.922-0.961). The eGFRcr (NEW) showed slightly better discrimination and reclassification than the eGFRcr. However, the new cre-atinine and cystatin C equation [eGFRcr-cys (NEW)] performed similarly to the current creatinine and cystatin C equation. Furthermore, eGFRcr-cys (NEW) did not show better performance for KFRT risk than eGFRcr (NEW). Conclusion: Both the current and the new CKD-EPI equations showed excellent predictive performance for 5-year KFRT risk in Kore-an patients with CKD. These new equations need to be further tested for other clinical outcomes in Koreans. | - |
dc.format.extent | 11 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | KOREAN SOC NEPHROLOGY | - |
dc.title | Predictive performance of the new race-free Chronic Kidney Disease Epidemiology Collaboration equations for kidney outcome in Korean patients with chronic kidney disease | - |
dc.type | Article | - |
dc.identifier.wosid | 001124236700008 | - |
dc.identifier.doi | 10.23876/j.krcp.22.158 | - |
dc.identifier.bibliographicCitation | KIDNEY RESEARCH AND CLINICAL PRACTICE, v.42, no.4, pp 501 - 511 | - |
dc.identifier.kciid | ART003004678 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.scopusid | 2-s2.0-85166409844 | - |
dc.citation.endPage | 511 | - |
dc.citation.startPage | 501 | - |
dc.citation.title | KIDNEY RESEARCH AND CLINICAL PRACTICE | - |
dc.citation.volume | 42 | - |
dc.citation.number | 4 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Chronic Kidney Disease Epidemiology Collaboration | - |
dc.subject.keywordAuthor | Creatinine | - |
dc.subject.keywordAuthor | Cystatin C | - |
dc.subject.keywordAuthor | Kidney failure with renal replacement therapy | - |
dc.subject.keywordPlus | GLOMERULAR-FILTRATION-RATE | - |
dc.subject.keywordPlus | BETA-TRACE PROTEIN | - |
dc.subject.keywordPlus | SERUM CREATININE | - |
dc.subject.keywordPlus | NATIONAL-HEALTH | - |
dc.subject.keywordPlus | MEASURED GFR | - |
dc.subject.keywordPlus | CKD | - |
dc.subject.keywordPlus | ESRD | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | ACCURACY | - |
dc.relation.journalResearchArea | Urology & Nephrology | - |
dc.relation.journalWebOfScienceCategory | Urology & Nephrology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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