The Fatty Liver Index's Association with Incident Chronic Kidney Disease in Korean Middle-Aged Adults: A Community-Based Cohort Study
DC Field | Value | Language |
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dc.contributor.author | Lee, Hyun Hee | - |
dc.contributor.author | Ro, Han | - |
dc.contributor.author | Jung, Ji Yong | - |
dc.contributor.author | Chang, Jae Hyun | - |
dc.contributor.author | Chung, Wookyung | - |
dc.contributor.author | Kim, Ae Jin | - |
dc.date.accessioned | 2024-04-18T01:00:25Z | - |
dc.date.available | 2024-04-18T01:00:25Z | - |
dc.date.issued | 2024-03 | - |
dc.identifier.issn | 2077-0383 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/90988 | - |
dc.description.abstract | (1) Background: The relationship between nonalcoholic fatty liver disease (NAFLD) and incident chronic kidney disease (CKD) is unclear, and long-term follow-up data are limited. Therefore, this study aimed to evaluate whether NAFLD, as assessed by the fatty liver index (FLI), could predict the development of CKD in a community-based Korean cohort over 16 years. (2) Methods: Among the 10,030 total participants, 7778 patients without CKD were selected from the Korean Genome and Epidemiology Study (KoGES). The FLI grade ranged from 0 to 100 and was divided into three groups: low (FLI, <30), intermediate (FLI, 30-59), and high (FLI, >= 60). An estimated glomerular filtration rate (eGFR) of <60 mL/min/1.73 m(2) or the development of proteinuria was considered to indicate incident CKD. (3) Results: During the 16-year follow-up period, 919 individuals (11.8%) developed CKD. The HRs of incident CKD in the intermediate FLI group (30-59) and high FLI group (>= 60) increased compared with the reference low FLI group (<30) after adjusting for potentially confounding variables. NAFLD, as assessed by the FLI, was an independent risk factor for CKD. (4) Conclusions: Our findings suggest that the FLI, a simple surrogate biomarker of fatty liver disease, may be used to identify people at high risk of incident CKD in clinical practice. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | MDPI | - |
dc.title | The Fatty Liver Index's Association with Incident Chronic Kidney Disease in Korean Middle-Aged Adults: A Community-Based Cohort Study | - |
dc.type | Article | - |
dc.identifier.wosid | 001193368600001 | - |
dc.identifier.doi | 10.3390/jcm13061616 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL MEDICINE, v.13, no.6 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.scopusid | 2-s2.0-85188992786 | - |
dc.citation.title | JOURNAL OF CLINICAL MEDICINE | - |
dc.citation.volume | 13 | - |
dc.citation.number | 6 | - |
dc.type.docType | Article | - |
dc.publisher.location | 스위스 | - |
dc.subject.keywordAuthor | fatty liver index | - |
dc.subject.keywordAuthor | chronic kidney disease | - |
dc.subject.keywordAuthor | estimated glomerular filtration rate | - |
dc.subject.keywordAuthor | proteinuria | - |
dc.subject.keywordPlus | LIPID-ACCUMULATION PRODUCT | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | VALIDATION | - |
dc.subject.keywordPlus | STEATOSIS | - |
dc.subject.keywordPlus | NAFLD | - |
dc.subject.keywordPlus | CKD | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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