Alkaloids of NIRAM, natural dye from Polygonum tinctorium, and their anti-inflammatory activities
DC Field | Value | Language |
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dc.contributor.author | Kim, Dong Hyun | - |
dc.contributor.author | Kim, Chung Sub | - |
dc.contributor.author | Subedi, Lalita | - |
dc.contributor.author | Kim, Sun Yeou | - |
dc.contributor.author | Lee, Kang Ro | - |
dc.date.available | 2020-02-27T02:21:28Z | - |
dc.date.created | 2020-02-04 | - |
dc.date.issued | 2019-10-10 | - |
dc.identifier.issn | 0040-4039 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/914 | - |
dc.description.abstract | Phytochemical investigation of EtOH extract of NIRAM, natural dye from Polygonum tinctorium, resulted in the purification of nine alkaloid compounds (1-9) including four new compounds (1-4). Structures of these new compounds were elucidated by 1D and 2D NMR (H-1 and C-13 NMR, H-1-H-1 COSY, H-1-C-13 HSQC, H-1-C-13 HMBC), IR, UV, HR-ESI-MS, and ECD spectra. Isolated compounds (1-9) were tested for their inhibitory effects on nitric oxide (NO) production in lipopolysaccharide (LPS)-activated BV-2 cells. Compounds 1-3, 5, and 7 showed potent NO production inhibitory activities, with IC50 values of 3.88-22.87 mu M. (C) 2019 Elsevier Ltd. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
dc.relation.isPartOf | TETRAHEDRON LETTERS | - |
dc.subject | KAEMPFEROL | - |
dc.subject | C-13 | - |
dc.title | Alkaloids of NIRAM, natural dye from Polygonum tinctorium, and their anti-inflammatory activities | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000489357900008 | - |
dc.identifier.doi | 10.1016/j.tetlet.2019.151130 | - |
dc.identifier.bibliographicCitation | TETRAHEDRON LETTERS, v.60, no.41 | - |
dc.identifier.scopusid | 2-s2.0-85072085301 | - |
dc.citation.title | TETRAHEDRON LETTERS | - |
dc.citation.volume | 60 | - |
dc.citation.number | 41 | - |
dc.contributor.affiliatedAuthor | Subedi, Lalita | - |
dc.contributor.affiliatedAuthor | Kim, Sun Yeou | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | NIRAM | - |
dc.subject.keywordAuthor | Polygonum tinctorium | - |
dc.subject.keywordAuthor | Indole alkaloids | - |
dc.subject.keywordAuthor | Anti-Inflammatory activities | - |
dc.subject.keywordPlus | KAEMPFEROL | - |
dc.subject.keywordPlus | C-13 | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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