Maximization of cytochrome C oxidase enzyme activity by optimizing color conversion from red organic light-emitting diodes
DC Field | Value | Language |
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dc.contributor.author | Tri, T.T. | - |
dc.contributor.author | Lim, Saebin | - |
dc.contributor.author | Dang, N.N. | - |
dc.contributor.author | Chae, Heeyeop | - |
dc.contributor.author | Kim, Haejung | - |
dc.contributor.author | Lee, Hyun Jong | - |
dc.contributor.author | Jo, Deok Su | - |
dc.contributor.author | Cho, Sung Min | - |
dc.date.accessioned | 2024-07-06T11:30:44Z | - |
dc.date.available | 2024-07-06T11:30:44Z | - |
dc.date.issued | 2024-06 | - |
dc.identifier.issn | 2352-9407 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/91745 | - |
dc.description.abstract | Photobiomodulation (PBM) therapy using red and near-infrared (NIR) light can effectively activate cytochrome C oxidase (CCO) enzyme to promote wound healing in living organisms. To maximize this therapeutic effect, the use of a light source with a spectrum absorbed by the CCO enzyme is necessary. A red/NIR light source optimized for CCO enzyme was obtained by partially color-converting a red organic light-emitting diode with copper indium sulfide/zinc sulfide quantum dots (QDs). To increase color conversion efficiency, the dispersion of QDs was improved by using a fibrous color conversion layer (FCCL). By optimizing the QD content in the FCCL, a red/NIR light source similar to the absorption spectrum of CCO enzyme was obtained with a spectral matching ratio of 81.7 %. When this light source was used in PBM therapy, it was experimentally verified that it showed a much faster wound closure effect compared to general red light, and it was proven that this was due to increased activity of the CCO enzyme. This study is a method of obtaining a red/NIR light source for PBM suitable for a specific enzyme performing a specific function, and is particularly useful due to its excellent form factor of being large, thin, and flexible. © 2024 Elsevier Ltd | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier | - |
dc.title | Maximization of cytochrome C oxidase enzyme activity by optimizing color conversion from red organic light-emitting diodes | - |
dc.type | Article | - |
dc.identifier.wosid | 001240853900001 | - |
dc.identifier.doi | 10.1016/j.apmt.2024.102223 | - |
dc.identifier.bibliographicCitation | Applied Materials Today, v.38 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85192681554 | - |
dc.citation.title | Applied Materials Today | - |
dc.citation.volume | 38 | - |
dc.type.docType | Article | - |
dc.publisher.location | 네델란드 | - |
dc.subject.keywordAuthor | CIS/ZnS quantum dot | - |
dc.subject.keywordAuthor | Color conversion | - |
dc.subject.keywordAuthor | cytochrome C oxidase enzyme | - |
dc.subject.keywordAuthor | Organic light-emitting diode | - |
dc.subject.keywordAuthor | Photobiomodulation | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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