A Consolidated Understanding of the Contribution of Redox Dysregulation in the Development of Hearing Impairment
DC Field | Value | Language |
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dc.contributor.author | Yeo, Xin Yi | - |
dc.contributor.author | Kwon, Soohyun | - |
dc.contributor.author | Rinai, Kimberley R. | - |
dc.contributor.author | Lee, Sungsu | - |
dc.contributor.author | Jung, Sangyong | - |
dc.contributor.author | Park, Raekil | - |
dc.date.accessioned | 2024-07-25T12:00:24Z | - |
dc.date.available | 2024-07-25T12:00:24Z | - |
dc.date.issued | 2024-05 | - |
dc.identifier.issn | 2076-3921 | - |
dc.identifier.issn | 2076-3921 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/92069 | - |
dc.description.abstract | The etiology of hearing impairment is multifactorial, with contributions from both genetic and environmental factors. Although genetic studies have yielded valuable insights into the development and function of the auditory system, the contribution of gene products and their interaction with alternate environmental factors for the maintenance and development of auditory function requires further elaboration. In this review, we provide an overview of the current knowledge on the role of redox dysregulation as the converging factor between genetic and environmental factor-dependent development of hearing loss, with a focus on understanding the interaction of oxidative stress with the physical components of the peripheral auditory system in auditory disfunction. The potential involvement of molecular factors linked to auditory function in driving redox imbalance is an important promoter of the development of hearing loss over time. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | MDPI | - |
dc.title | A Consolidated Understanding of the Contribution of Redox Dysregulation in the Development of Hearing Impairment | - |
dc.type | Article | - |
dc.identifier.wosid | 001233099700001 | - |
dc.identifier.doi | 10.3390/antiox13050598 | - |
dc.identifier.bibliographicCitation | ANTIOXIDANTS, v.13, no.5 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.scopusid | 2-s2.0-85194087325 | - |
dc.citation.title | ANTIOXIDANTS | - |
dc.citation.volume | 13 | - |
dc.citation.number | 5 | - |
dc.type.docType | Review | - |
dc.publisher.location | 스위스 | - |
dc.subject.keywordAuthor | hearing loss | - |
dc.subject.keywordAuthor | auditory deficit | - |
dc.subject.keywordAuthor | cochlea function | - |
dc.subject.keywordAuthor | redox imbalance | - |
dc.subject.keywordAuthor | oxidative stress | - |
dc.subject.keywordPlus | INDUCED OXIDATIVE STRESS | - |
dc.subject.keywordPlus | HAIR-CELL STEREOCILIA | - |
dc.subject.keywordPlus | INNER-EAR | - |
dc.subject.keywordPlus | NOISE EXPOSURE | - |
dc.subject.keywordPlus | SODIUM THIOSULFATE | - |
dc.subject.keywordPlus | LIPID-PEROXIDATION | - |
dc.subject.keywordPlus | FREE-RADICALS | - |
dc.subject.keywordPlus | OTITIS-MEDIA | - |
dc.subject.keywordPlus | MITOCHONDRIAL DYSFUNCTION | - |
dc.subject.keywordPlus | SIGNALING PATHWAYS | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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