Oxidative stress-mediated deleterious effects of hypoxia in the brackish water flea Diaphanosoma celebensis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Yoseop | - |
dc.contributor.author | Kim, Duck-Hyun | - |
dc.contributor.author | Lee, Jin-Sol | - |
dc.contributor.author | Lee, Min-Chul | - |
dc.contributor.author | Kim, Hyung Sik | - |
dc.contributor.author | Maszczyk, Piotr | - |
dc.contributor.author | Sakakura, Yoshitaka | - |
dc.contributor.author | Yang, Zhou | - |
dc.contributor.author | Hagiwara, Atsushi | - |
dc.contributor.author | Park, Heum Gi | - |
dc.contributor.author | Lee, Jae-Seong | - |
dc.date.accessioned | 2024-07-30T11:30:23Z | - |
dc.date.available | 2024-07-30T11:30:23Z | - |
dc.date.issued | 2024-08 | - |
dc.identifier.issn | 0025-326X | - |
dc.identifier.issn | 1879-3363 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/92093 | - |
dc.description.abstract | In this study, we investigated the acute toxicity, in vivo effects, oxidative stress, and gene expression changes caused by hypoxia on the brackish water flea Diaphanosoma celebensis. The no-observed-effect concentration (NOEC) of 48 h of hypoxia exposure was found to be 2 mg/L O2. Chronic exposure to NOEC caused a significant decline in lifespan but had no effect on total fecundity. The induction of reactive oxygen species increased in a time-dependent manner over 48 h, whereas the content of antioxidant enzymes (superoxide dismutase and catalase) decreased. The transcription and translation levels were modulated by hypoxia exposure. In particular, a significant increase in hemoglobin level was followed by up-regulation of hypoxia-inducible factor 1 alpha gene expression and activation of the mitogen-activated protein kinase pathway. In conclusion, our findings provide a better understanding of the molecular mechanism of the adverse effects of hypoxia in brackish water zooplankton. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
dc.title | Oxidative stress-mediated deleterious effects of hypoxia in the brackish water flea Diaphanosoma celebensis | - |
dc.type | Article | - |
dc.identifier.wosid | 001261572900001 | - |
dc.identifier.doi | 10.1016/j.marpolbul.2024.116633 | - |
dc.identifier.bibliographicCitation | MARINE POLLUTION BULLETIN, v.205 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85196810991 | - |
dc.citation.title | MARINE POLLUTION BULLETIN | - |
dc.citation.volume | 205 | - |
dc.type.docType | Article | - |
dc.publisher.location | 영국 | - |
dc.subject.keywordAuthor | Hypoxia | - |
dc.subject.keywordAuthor | Oxidative stress | - |
dc.subject.keywordAuthor | Antioxidant system | - |
dc.subject.keywordAuthor | HIF-1 alpha pathway | - |
dc.subject.keywordAuthor | Diaphanosoma celebensis | - |
dc.subject.keywordPlus | MESSENGER-RNA EXPRESSION | - |
dc.subject.keywordPlus | LITOPENAEUS-VANNAMEI | - |
dc.subject.keywordPlus | METABOLIC-RESPONSES | - |
dc.subject.keywordPlus | TIGRIOPUS-JAPONICUS | - |
dc.subject.keywordPlus | SIGNALING PATHWAYS | - |
dc.subject.keywordPlus | LIFE PARAMETERS | - |
dc.subject.keywordPlus | CLIMATE-CHANGE | - |
dc.subject.keywordPlus | SHRIMP | - |
dc.subject.keywordPlus | HEMOGLOBIN | - |
dc.subject.keywordPlus | HIF-1 | - |
dc.relation.journalResearchArea | Environmental Sciences & Ecology | - |
dc.relation.journalResearchArea | Marine & Freshwater Biology | - |
dc.relation.journalWebOfScienceCategory | Environmental Sciences | - |
dc.relation.journalWebOfScienceCategory | Marine & Freshwater Biology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.