桂枝芍藥知母湯이 Acetic Acid에 의한 통증에 미치는 영향
DC Field | Value | Language |
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dc.contributor.author | 노희엽 | - |
dc.contributor.author | 김연섭 | - |
dc.contributor.author | 김도훈 | - |
dc.date.available | 2020-02-28T05:41:32Z | - |
dc.date.created | 2020-02-12 | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1738-6640 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/9279 | - |
dc.description.abstract | Objectives : We want to know the effect of Gyejakjimo-tang in mice model of acute pain. Methods : We investigated writhing reflex in mice with acetic acid-induced abdominal pain using mice, we observed c-Fos protien expression by immunohistochemistry dyeing method in the paraventricular nucleus(PVN) and supraoptic nucleus(SON) of the hypothalamus. Results : All of Gyejakjimo-tang treated group suppressed acetic acid-induced writhing response as acetic acid injuction group, but in 100㎎/㎏ Gyejakjimo-tang treated group and 200㎎/㎏ Gyejakjimo-tang treated groups represernted significance. All of Gyejakjimo-tang treated groups(50, 100 and 200㎎/㎏ Gyejakjimo-tang-treated group), Fos-positive cells in PNV significantly decreased as acetic acid injuction group, and All of Gyejakjimo-tang-treated groups Fos-positive cells in SON significantly decreased as acetic acid injuction group. Conclusions : The present results showed that the mice pre-treated with the aqueous extract of Gyejakjimo-tang showed analgesic effect on acetic acid-induced abdominal pain. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 대한한방안이비인후피부과학회 | - |
dc.relation.isPartOf | 한방안이비인후피부과학회지 | - |
dc.title | 桂枝芍藥知母湯이 Acetic Acid에 의한 통증에 미치는 영향 | - |
dc.title.alternative | The Effect of Gyejakjimo-tang on c-Fos Expression in Mice Model of Acute Pain | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 2 | - |
dc.identifier.doi | 10.6114/jkood.2016.29.3.150 | - |
dc.identifier.bibliographicCitation | 한방안이비인후피부과학회지, v.29, no.3, pp.150 - 158 | - |
dc.identifier.kciid | ART002133955 | - |
dc.citation.endPage | 158 | - |
dc.citation.startPage | 150 | - |
dc.citation.title | 한방안이비인후피부과학회지 | - |
dc.citation.volume | 29 | - |
dc.citation.number | 3 | - |
dc.contributor.affiliatedAuthor | 노희엽 | - |
dc.contributor.affiliatedAuthor | 김연섭 | - |
dc.contributor.affiliatedAuthor | 김도훈 | - |
dc.subject.keywordAuthor | Gyejakjimo-tang | - |
dc.subject.keywordAuthor | pain | - |
dc.subject.keywordAuthor | acetic acid | - |
dc.subject.keywordAuthor | c-Fos | - |
dc.description.journalRegisteredClass | kci | - |
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