PROSPECTIVE VALIDATION OF REPEATABILITY OF SHEAR WAVE DISPERSION IMAGING FOR EVALUATION OF NON-ALCOHOLIC FATTY LIVER DISEASE
- Authors
- Yoo, Jeongin; Lee, Jeong Min; Joo, Ijin; Lee, Dong Ho; Yoon, Jeong Hee; Kang, Hyo-Jin; Ahn, Su Joa
- Issue Date
- Oct-2019
- Publisher
- ELSEVIER SCIENCE INC
- Keywords
- Fatty liver disease; Steatosis; Dispersion; Shear wave elastography; Repeatability
- Citation
- ULTRASOUND IN MEDICINE AND BIOLOGY, v.45, no.10, pp.2688 - 2696
- Journal Title
- ULTRASOUND IN MEDICINE AND BIOLOGY
- Volume
- 45
- Number
- 10
- Start Page
- 2688
- End Page
- 2696
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/937
- DOI
- 10.1016/j.ultrasmedbio.2019.06.411
- ISSN
- 0301-5629
- Abstract
- This study was aimed at evaluating the intra-observer repeatability of shear wave dispersion imaging (SWDI) for evaluation of non-alcoholic fatty liver disease and assessing inter-observer repeatability in asymptomatic volunteers, using a commercial ultrasound system. This prospective study was approved by our institutional review board and informed consent was obtained from all patients. In group I composed of patients with suspected or alleged non-alcoholic fatty liver disease (n = 71), two sessions of SWDI were performed by one radiologist for evaluation of intra-observer repeatability. In group II composed of asymptomatic volunteers (n = 19), three independent sessions were performed by three radiologists. Intra-observer and inter-observer repeatability was assessed using intra-class correlation coefficients (ICCs). For intra-observer repeatability, the ICC was 0.955 (95% confidence interval: 0.926-0.973), and subgroup analysis revealed that body mass index, ultrasound steatosis grade and liver function test abnormalities did not affect ICCs. The ICC for inter-observer repeatability was 0.800 (95% confidence interval: 0.572-0.916). Thus, SWDI had excellent intra-and inter-observer repeatability. (C) 2019 World Federation for Ultrasound in Medicine & Biology. All rights reserved.
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