Effect of Short-Term Steroid Therapy on Early Recurrence During the Blanking Period After Catheter Ablation of Atrial Fibrillation
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Yoo Ri | - |
dc.contributor.author | Nam, Gi-Byoung | - |
dc.contributor.author | Han, Seungbong | - |
dc.contributor.author | Kim, Sung-Hwan | - |
dc.contributor.author | Kim, Ki-Hun | - |
dc.contributor.author | Lee, Sulhee | - |
dc.contributor.author | Kim, Jun | - |
dc.contributor.author | Choi, Kee-Joon | - |
dc.contributor.author | Kim, You-Ho | - |
dc.date.available | 2020-02-28T07:42:17Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2015-12 | - |
dc.identifier.issn | 1941-3149 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/9886 | - |
dc.description.abstract | Background Early recurrence (ER) of atrial tachyarrhythmias during the first 3 months (blanking period) after atrial fibrillation ablation can be highly symptomatic, often requiring emergency treatment. Short-term steroid therapy may suppress ER during the blanking period. Methods and Results We prospectively enrolled 138 patients who were randomly assigned to 2 groups (steroid group and control group). An intravenous bolus of 0.5 mg/kg of methylprednisolone for 2 days followed by 12 mg daily of oral methylprednisolone for 4 days was given to the steroid group patients. The primary end point was ER during the blanking period (3 months post ablation). During the blanking period, 51 of the 138 (37.0%) patients experienced ER after atrial fibrillation ablation. The steroid group had a lower rate of ER than the control group (15/64 [23.4%] versus 36/74 [48.6%], P=0.003). There was no difference between the 2 groups about late recurrence during a 24-month follow-up (log-rank test, P=0.918). In a multivariate analysis, short-term steroid therapy was independently associated with a lower rate of ER during the blanking period (adjusted OR, 0.45; 95% confidence interval, 0.25-0.83; P=0.01). Conclusions Periprocedural short-term moderate intensity steroid therapy reduces ER (approximate to 3 months) after catheter ablation of atrial fibrillation. It is not effective in preventing late (3 approximate to 24 m) atrial fibrillation recurrence. Clinical Trial Registration URL: www.who.int/ictrp; Unique identifier: KCT0000107. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.relation.isPartOf | CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY | - |
dc.subject | PULMONARY VEIN ISOLATION | - |
dc.subject | RADIOFREQUENCY LESIONS | - |
dc.subject | TACHYARRHYTHMIAS | - |
dc.subject | CARDIOVERSION | - |
dc.subject | INFLAMMATION | - |
dc.subject | PREVENTION | - |
dc.subject | PREVALENCE | - |
dc.subject | PREDICTORS | - |
dc.subject | CONDUCTION | - |
dc.title | Effect of Short-Term Steroid Therapy on Early Recurrence During the Blanking Period After Catheter Ablation of Atrial Fibrillation | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000366604600012 | - |
dc.identifier.doi | 10.1161/CIRCEP.115.002957 | - |
dc.identifier.bibliographicCitation | CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, v.8, no.6, pp.1366 - 1372 | - |
dc.identifier.scopusid | 2-s2.0-84950153041 | - |
dc.citation.endPage | 1372 | - |
dc.citation.startPage | 1366 | - |
dc.citation.title | CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY | - |
dc.citation.volume | 8 | - |
dc.citation.number | 6 | - |
dc.contributor.affiliatedAuthor | Han, Seungbong | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | atrial fibrillation | - |
dc.subject.keywordAuthor | catheter ablation | - |
dc.subject.keywordAuthor | glucocorticoids | - |
dc.subject.keywordAuthor | methylprednisolone | - |
dc.subject.keywordAuthor | multivariate analysis | - |
dc.subject.keywordPlus | PULMONARY VEIN ISOLATION | - |
dc.subject.keywordPlus | RADIOFREQUENCY LESIONS | - |
dc.subject.keywordPlus | TACHYARRHYTHMIAS | - |
dc.subject.keywordPlus | CARDIOVERSION | - |
dc.subject.keywordPlus | INFLAMMATION | - |
dc.subject.keywordPlus | PREVENTION | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | PREDICTORS | - |
dc.subject.keywordPlus | CONDUCTION | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.