Anchoring Transitions of Liquid Crystals for Optical Amplification of Phospholipid Oxidation Inhibition by Ascorbic Acid
- Authors
- Zhang, Minmin; Jang, Chang-Hyun
- Issue Date
- Dec-2015
- Publisher
- JAPAN SOC ANALYTICAL CHEMISTRY
- Keywords
- Ascorbic acid; antioxidant; phospholipids; liquid crystals; anchoring transition
- Citation
- ANALYTICAL SCIENCES, v.31, no.12, pp.1329 - 1333
- Journal Title
- ANALYTICAL SCIENCES
- Volume
- 31
- Number
- 12
- Start Page
- 1329
- End Page
- 1333
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/9895
- DOI
- 10.2116/analsci.31.1329
- ISSN
- 0910-6340
- Abstract
- There is considerable evidence that the antioxidant property of ascorbic acid (AH) is effective for reducing oxidative stress of phospholipids. Herein, a liquid crystals (LCs)-based method was developed for the optical amplification of resistance to phospholipid oxidation by AH. Phospholipid peroxidation initiated by free radicals was monitored from a homeotropic-to-planar anchoring transition of LCs via polarized optical microscopy. Alternatively, consistent homeotropic anchoring of LCs was observed when the oxidation caused by free radicals was blocked by AH.
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