ScholarWorks@Gachon: An, Seong Soo A.

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An, Seong Soo A. (안성수)

BioNano Technology (Department of BioNano Technology)

Research Area: 신경과학, 퇴행성뇌질환, 바이오마커/치료제, neurosciences, Neurodegenerative diseases, biomarkers/therapeutics

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s disease:54||Alzheimer&apos:50||mutation:16||Alzheimer’s disease:13||Mutation:10||diagnosis:8||oxidative stress:7||neuroprotection:7||PSEN1:7||Alzheimer's disease:6||Amyloidbeta:6||plasma:5||prion:5||neuroinflammation:4||Dementia:4||sequencing:4||genetics:4||therapy:4||cytotoxicity:4||biomarker:4||antiacetylcholine esterase activity:4||Multimer detection system:4||presenilin1:4||protein corona:4||acetylcholinesterase:3||neurodegenerative diseases:3||SARSCoV2:3||Amyloid beta:3||Neurodegeneration:3||blood:3||Biomarkers:3||graphene:3||nanomaterials:3||APOE:3||fibrinogen:3||presenilin 2:3||presenilin2:3||amyloid precursor protein:3||silica:3||nanotoxicity:3||Next generation sequencing:3||amyloidbeta:3||Plasmodium vivax:3||Cytotoxicity:3||cancer:3||ELISA:3||oligomer:3||Tau:3||EOAD:3||mild cognitive impairment:3||TDP43:3||Natural products:3||antibacterial:3||Inflammation:3||Biomarker:3||multimer detection system:3||safety:2||Presenilin1:2||amyloid beta:2||silica coating:2||Presenilin1:2||crosslinking:2||small vessel disease:2||ligand:2||dementia:2||machine learning:2||CJD:2||Bloodbased biomarker:2||COVID19:2||diagnostics:2||TARDBP:2||transmissible spongiform encephalopathies:2||Essential oils:2||doxorubicin:2||antibiotics:2||ultracentrifugation:2||vascular cognitive impairment:2||NGS:2||whole exome sequencing:2||mutations:2||early onset Alzheimer&apos:2||early onset Alzheimer's disease:2||zinc oxide:2||earlyonset Alzheimer&apos:2||efficacy:2||αSynuclein:2||amyloid:2||nanozymes:2||neurodegeneration:2||PSEN1 mutation:2||neurodegenerative disease:2||neurodegenerative disorders:2||apolipoprotein structure:2||F:2||Thailand:2||epitope mapping:2||no observed adverse effect level:2||Diagnosis:2||exosome:2||autophagy:2||oligomerization:2||ROS:2||Raman spectroscopy:2||Tissue engineering:2||Neurodegenerative disease:2||Comorbidity:2||frontotemporal dementia:2||Neuroimaging:2||Parkinson’s disease:2||Neuroinflammation:2||biomarkers:2||Neuroprotection:2||biosensor:2||Pittsburgh compound B:2||Drug delivery:2||Plasma:2||Fluid biomarkers:2||presenilin:2||brain homogenate:2||prion protein:2||90day oral dose toxicity:2||haploinsufficiency:2||Novel mutation:2||Semen:2||CreutzfeldtJakob disease:2||purification:2||Sensitivity:2||Oligomer:2||reactive oxygen species:2||Specificity:2||ARSACS:2||GRN:2||aggregation:2||Cerebrospinal fluid:2||immobilization:2||alphasynuclein:2||Cyclooxygenase:2||Optical:2||risk modifiers:2||Oxidative stress:2||nanoparticles:2||Structural prediction:2||GerstmannStrausslerScheinker disease:1||GerstmannStrausslerScheinker disease (GSS):1||GerstmannStrausslerScheinker syndrome:1||Graphene oxide:1||Green fluorescent protein:1||Guettarda speciosa:1||H2O2 induced stress:1||H2O2induced oxidative stress:1||H2O2induced oxidative stress in SHSY5Y:1||HDLS:1||Hemolysis:1||Hippocampus:1||Homopolymer:1||IAPP:1||Immunoassay:1||Immunohistochemistry:1||In silico:1||Individual Brain Atlases using Statistical:1||Inexpensive:1||Infectious prion proteins:1||Influenza A/B:1||Influenza vaccine:1||Interferon:1||Interleukin:1||Korea:1||Korean:1||L232P mutation:1||LDT:1||Lactate dehydrogenase leakage assay:1||Lasianthus:1||Leu159Pro:1||Limbicpredominant agerelated TDP43 encephalopathy:1||Longterm storage:1||LowDensity Lipoprotein Receptor (LDLR):1||LpPLA(2):1||MAPT:1||MDS:1||MGB axis:1||MR imaging:1||MRI:1||Machine Learning:1||Magnetic microparticles:1||Malaria vaccine:1||Medial temporal lobe:1||Mesoporous:1||Mesoporous silica NPs:1||Microfiber:1||Microfluidics:1||Microspheres:1||Microtubes:1||Mild Cognitive Impairment:1||Mitochondria:1||Modelling:1||Molecular docking:1||Multifunctional:1||Multimer detection systemoligomeric A:1||Murraya koenigii:1||Muscarinic and nicotinic receptors:1||Mutations:1||Mvasi:1||Nanofiber:1||Nanoparticle:1||Nanotoxicity:1||Nanovesicles:1||Neuroblastoma:1||Neurodegenerative genes:1||Neurofibrillary tangles:1||Neuroprotective:1||Neuroprotective effects:1||Neuropsychological Test:1||Neuropsychology:1||NfL:1||Novel APP Val669Leu mutation:1||Nucleicacid chip based:1||O157:H7:1||Oligomerization:1||Oligomers:1||Omicron:1||Onepot method:1||OptiMAL:1||Oxindole alkaloids:1||P.Ala285Val:1||PCR analysis:1||PET:1||PFA100:1||PGRN:1||PLGA:1||PRNP:1||PRNP Val180Ile mutation:1||PRNP gene:1||PSEN1 Thr116Ile mutation:1||PSEN2:1||PSEN2 Gly56Ser mutation:1||PSEN2 TM5:1||PSEN2 mutation:1||Pandanus:1||Pandanus amaryllifolius:1||Pandanus tectorius:1||Parametric Mapping:1||Parkinson&apos:1||Parkinson's disease:1||Parkinsonism:1||Pathogenic:1||Photothermal heating:1||Phytosterols:1||Planar:1||Plasma A beta oligomer:1||Plasma Aβ Oligomer:1||Plasma test:1||Platelet:1||Ployphen2:1||Poisonous plants:1||Polydopamine:1||Polymer:1||Polymerprotein coreshell particle:1||Polymorphism:1||Presenilin 1:1||Presenilin 1 mutation:1||Presenilin 1 protein structure:1||Presenilin 2:1||Presenilin 2 mutation:1||Presenilin 2 protein structure:1||Presymptomatic:1||Prion:1||Prion disease:1||Prions disease:1||Priori protein:1||Protease:1||Protein adsorption:1||Protein aggregation:1||Protein folding:1||Protein oligomers:1||Proteinpolymer nanoparticle:1||Proteinopathy:1||Proteomics:1||PvTARAg55:1||Pvs47:1||Pvs48/45:1||RNA array:1||RNA sequencing:1||Rapid diagnostic test:1||Reactive oxygen species:1||Realtime RT PCR:1||Realtime monitoring:1||Regulatory:1||Republic of Korea:1||Reversible:1||ReyOsterrieth Complex Figure:1||Rubiaceae:1||Rutaceae:1||SACS:1||SERS:1||SHSY5Y cells:1||SIFT:1||SNPs:1||SORL1:1||SPR:1||SVD:1||Sacsin:1||Secretomics:1||Secretory protein:1||Seminal vesicles:1||Silver nanoparticles:1||Sizecontrol:1||Spices:1||Splice site mutation:1||Sporadic early onset Alzheimer’s disease:1||Standard deviation:1||Stimuliresponsive drug release:1||Strategies:1||Surface engineering:1||Surface orientation:1||Surface topography:1||Surgery:1||Survival:1||Synthetic amyloidbeta:1||Syzygium aromaticum:1||T1 contrast imaging:1||T2DM:1||TAFI:1||TERS:1||TNFAIP3 gene:1||TOMM40:1||Tarenna:1||Targeting strategy:1||Testes:1||Therapeutics:1||Therapy:1||Thioflavin T:1||Thr119Ile mutation:1||Thrombin activatable fibrinolysis inhibitor (TAFI):1||Thymol:1||Toxicity:1||Trail Making Test:1||Translational Medical Research:1||Transmissible spongiform encephalopathy:1||Traumatic brain injury:1||Tropane alkaloids:1||Trp165Cys:1||Tumornecrosis factor:1||Tyr225Cys mutation:1||Tyr389His:1||Uncaria:1||V180I mutation:1||V604M:1||VCP:1||VDR polymorphism:1||VEGF:1||VOCs:1||Vascular graft:1||Vegzelma:1||Virus culture:1||Virusmimicking:1||Volumetry:1||Vomifoliol:1||Voxelbased morphometry:1||Whole Exome Sequence (WES) analysis:1||Wholeexome sequencing:1||Wuhan:1||ZnONPs:1||acne inversa:1||administration:1||alphaSynuclein:1||alphaterpinyl acetate:1||alternative splicing:1||alzheimer's disease:1||amyloid PET:1||amyloid aggregation:1||amyloid:1||amyloidopathy:1||amyloidosis:1||amyotrophic lateral sclerosis:1||analgesics:1||anethol:1||animal models:1||antiA beta fibrillization/oligomerization:1||antiAβ fibrilization/oligomerization:1||anticancer drug:1||antiglycation:1||antiprion agents:1||antibodies:1||anticancer:1||anticholinergics:1||apiole:1||apolipoprotein E:1||apolipoproteinE:1||apoptosis:1||atom transfer radical polymerization:1||atypical CreutzfeldtJakob disease:1||autoimmunity:1||basal ganglia:1||benghalensis:1||benzodiazepines:1||betaamyloid:1||bevacizumab:1||bioconjugation:1||bioimaging:1||bioactive compounds:1||biocompatibility:1||biofunctionalization:1||bioinformatic analysis:1||biological equivalence:1||biomaterial:1||biopharmaceuticals:1||biosensors:1||biosimilar:1||biosimilars:1||biotherapeutic agents:1||bloodbased biomarker:1||brain atrophy:1||brain tumor:1||breast cancer:1||calcitriol:1||cancer cell:1||carbon dots:1||cardamom:1||carvone:1||caspase mechanism:1||causative factor:1||cell growth:1||cell toxicity:1||cerebral palsy:1||cerebrospinal fluid:1||cerebrospinal fluid biomarkers:1||chitosan:1||cholinergic dysfunction:1||coagulation:1||cofactorembedded graphene:1||comparative analysis:1||complement component 3:1||confusion matrix:1||consumer characteristics:1||consumers:1||contrast agent:1||controlled drug release:1||controlled release:1||copy number variant:1||creatinine:1||cystamine conjugate:1||dementia disease:1||dementia risk:1||dementia with Lewy bodies:1||density functional theory:1||dequalinium:1||diagnostic:1||differently expressed genes:1||dilated cardiomyopathy:1||dill:1||disease:1||diseases:1||double mutations:1||drug delivery:1||drug discovery:1||dual bioimaging:1||early onset AD:1||electroencephalography:1||elisa:1||endogenous membrane peroxidase:1||enzymemimetics:1||epitope:1||erythropoietin:1||ethnic variability:1||exome sequencing:1||exosomes:1||experts:1||eyesclose:1||eyesopen:1||familial:1||fatal familial insomnia:1||fatal familial insomnia (FFI):1||fecal matter transfer:1||fennel:1||fibronectin:1||gammasecretase:1||gastric cancer:1||gemcitabine:1||gene interactions:1||generic drugs:1||genetic association:1||genetic biomarker:1||genetic factors:1||genetic molecular analysis:1||genetic testing:1||germfree animal:1||gold:1||gold nanorod:1||gold nanorods:1||graphene oxide:1||green:1||growth factor:1||gut dysbiosis:1||gut microbiota:1||gutbrain axis:1||hallucination:1||heat shock protein:1||herceptin:1||highthroughput screening multimer detection system (MDSHTS) assay:1||hippocampal atrophy:1||histagged enzyme:1||histidinetagged peptide:1||histidinetagged protein:1||household income:1||human dermal fibroblast:1||hyaluronan:1||hydrogel:1||imaging:1||imaging and therapeutics:1||immune dysfunctions:1||immunoassay:1||immunoassays:1||in silico modeling:1||in situ method:1||infectious prion proteins:1||influenza:1||iron oxide:1||ischemic stroke:1||islet amyloid polypeptide:1||isoflavone:1||isoform:1||laser irradiation:1||lipid rafts:1||loss of function:1||malaria vaccine:1||mammalian cells:1||membrane damage:1||mesoporous silicon:1||miRNAs:1||microstructure:1||microbial diversity:1||microbiotagutbrain axis:1||microchannel chip:1||microfibers:1||mitochondria targeting:1||mobile application:1||mode of action:1||molecular:1||monomer:1||motor diseases:1||mouse models:1||multitarget approach:1||multimer detection systemoligomeric amyloidbeta:1||mutations in presenilin 2:1||nanofibers:1||nanoheat island:1||nanohybrid:1||neurodegenerative:1||neuromodulators:1||neurotoxicity:1||neurotrauma:1||next generation sequencing:1||nextgeneration sequencing:1||nicotinamide:1||nonhuman primate:1||noncoding RNA:1||normal prion protein:1||novel mutation:1||oxide:1||p.Gly417Ala:1||p.His169Asn mutation:1||p53:1||pLDH:1||particle size:1||pathogen:1||pathogenesis:1||patient blood:1||peer review:1||penetration:1||persimmon fruit:1||phosphorylation:1||photopolymerization:1||photostability:1||physicochemical property:1||phyto carbazole alkaloid:1||plasminogen:1||poly(2acetamidoacrylic acid) hydrogel:1||polyclonal adjuvants:1||polymer:1||polymer composite:1||polymerprotein hybrid:1||polymorphism:1||polystyrene:1||postoperative cognitive changes:1||power spectrum density:1||predictability:1||presenilin 1:1||probiotic:1||probiotics:1||promoter polymorphism:1||protein:1||protein aggregates:1||protein aggregation:1||protein sensing:1||proteomic markers:1||protocol:1||proton pump inhibitors:1||quantitative:1||questionnaire survey:1||quorum sensing:1||realtime assay:1||recombinant:1||rectal cancer:1||reginal anesthesia:1||religiosa:1||resistance:1||resveratrol:1||risk factor:1||risk factors:1||risk modifier:1||s Disease:1||s dementia:1||sacsinopathy:1||scoring:1||semantic dementia:1||sensitivity:1||silica colloid:1||silica nanoparticles:1||silicacoated gold nanorod:1||specificity:1||statins:1||structure prediction:1||substrate specificity:1||support vector machine:1||surface charge:1||survey:1||synergistic effect:1||targeted:1||tau:1||therapeutics:1||thioflavin T:1||tissue engineering:1||tissue regeneration:1||total knee arthroplasty:1||toxic oligomer:1||toxicokinetics:1||trancriptome:1||transmission blocking vaccine:1||transthyretin:1||trastuzumab:1||tumor:1||tumor targeting:1||type 2 diabetes mellitus:1||vaccine development:1||vascular dementia:1||vitamin D:1||wholeexome sequencing:1||young onset Alzheimer&apos:1||youngonset stroke:1||zinc oxide nanoparticles:1||zombie fungus:1||3D modeling:1||βamyloid:1||3D bioprinting:1||3D spheroid:1||3D spheroids:1||50 genes:1||A beta 42/40 ratio:1||A beta oligomer:1||A betafibrilization:1||A betaoligomerization:1||A20 haploinsufficiency:1||ABCA7:1||ACE2:1||ACMGAMP guidelines:1||AD:1||ADP:1||APP:1||ATP productions:1||Active inclusion bodies:1||Adhesion:1||Agent Orange:1||Agglutination:1||Aggregation:1||Alpha synuclein:1||Alzheimer Disease:1||Alzheimer disease:1||Alzheimer's diseases:1||Alzheimers disease:1||Alzheimer’s Disease:1||Alzheimer’s diseases:1||Amyloid:1||Amyloid oligomers:1||Amyloid precursor protein:1||Amyloid status:1||Amyloidbeta protein:1||Amyloidbetaoligomer:1||Amyotrophic lateral sclerosis:1||Animal models:1||Antiprion:1||Anticholinergic action:1||Anticholinergic burden:1||Antigenspecific immune activation:1||Antioxidant:1||Arginineglycineaspartate peptide:1||Asia:1||Asian:1||Aspirin:1||Astrocyte:1||Ataxia:1||Atherosclerosis:1||Au NPs:1||AuNRs:1||Autologous:1||Avastin:1||Axial diffusivity:1||BBB:1||BDD electrode:1||BECN1:1||Berenil©:1||Biocompatible material:1||Biocompatible polymer:1||Biodegradable synthetic polymers:1||Bioinformatics:1||Biosensor:1||Blood biomarker:1||Blood brain barrier:1||Brain injury:1||Creader:1||C. difficile:1||C9orf72:1||CADASIL:1||CARASAL:1||CARASIL:1||CD44:1||CD9:1||CHMP2B:1||CLU variants:1||COX1:1||CRAT:1||CRISPRCas9:1||CSF:1||Cancerous cells:1||Carbazole alkaloids:1||Carom:1||Carvacrol:1||Central nervous system:1||Chemophotothermal therapy:1||Chromone:1||Chronic traumatic encephalopathy:1||Cisplatin:1||Clinical research:1||ClueGO:1||Clusterin:1||Cognitive impairment:1||Collagen:1||Controlled release:1||Cordyceps:1||Coronavirus:1||CreutzfeldtJakob disease (CJD):1||Creutzfelt Jakob disease:1||DFT:1||DNA primers:1||Darapladib:1||Derivatives:1||Design:1||Device:1||Diagnostic:1||Diffusor tensor imaging:1||Dirac point:1||Docking:1||Drug carrier:1||E. coli:1||E. coli O157:1||Early onset:1||Efficient cytotoxicity:1||Electrochemical:1||Electronphonon coupling:1||Endocytosis:1||Energy:1||Enterohemorrhagic:1||Enzyme inhibitors:1||Episodic memory:1||Epitope mapping:1||Extracellular matrix:1||FDA:1||FDA approved:1||FPPS:1||FTD:1||FUS:1||FeN single site:1||Fiber SPR:1||Fibrinogen:1||Fibrinolysis:1||Fluorescent:1||Fluorescent particle:1||Free:1||Functional nanocarrier:1||GATK:1||GWAS:1||Gastrointestinal:1||Gene panel:1||Genetic Research:1||Genetics:1||

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