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A novel 11β-HSD1 inhibitor ameliorates liver fibrosis by inhibiting the notch signaling pathway and increasing NK cell populationGo to Link

Kim, Ji Eun; Kim, Yun; Bae, Jiwon; Yoon, Eileen Laurel; Kim, Hyun Sung; Lee, Sung Ryol; Yoon, Tae Hyun; Jun, Dae Won

ArticleIssue Date2025CitationArchives of Pharmacal Research, v.48, no.2, pp 166 - 180Publisher대한약학회
SCIESCOPUS
ALS-L1023 from Melissa officinalis Alleviates Liver Fibrosis in a Non-Alcoholic Fatty Liver Disease ModelGo to Linkopen access

Lee, Eun Jeoung; Kim, Yun; Kim, Ji Eun; Yoon, Eileen Laurel; Lee, Sung Ryol; Jun, Dae Won

ArticleIssue Date2023CitationLife, v.13, no.1, pp 1 - 15PublisherMultidisciplinary Digital Publishing Institute (MDPI)
SCIESCOPUS
Assessing Post-Marketing Requirements for Orphan Drugs: A Cross-Sectional Analysis of FDA and EMA OversightGo to Linkopen access

Yu, Jae Hyeon; Lee, Sangwon; Kim, Yoon Jung; Kim, Won Young; Lee, Min Jung; Kim, Yun

ArticleIssue Date2024CitationClinical Pharmacology and Therapeutics, v.116, no.6, pp 1560 - 1571PublisherWILEY
SCIESCOPUS
Association of GLP-1 Receptor Agonists With Hepatic Decompensation in the All of Us Research ProgramGo to Linkopen access

Hwang, Inyoung; Kim, Yun; Lee, Sang Won

ArticleIssue Date2026CitationDIABETES OBESITY & METABOLISM, v.28, no.6, pp 4837 - 4846PublisherWILEY
SCIESCOPUS
Comparison of sarcopenia screening indices using serum creatinine and cystatin C in metabolic dysfunction-associated steatotic liver diseaseGo to Linkopen access

Hwang, Inyoung; Lee, Shi-Ra; Kim, Yun; Lee, Sang Won

ArticleIssue Date2025CitationFrontiers in Medicine, v.12, pp 1 - 10PublisherFrontiers Media S.A.
SCIESCOPUS
DLM-DTI: a dual language model for the prediction of drug-target interaction with hint-based learningGo to Linkopen access

Lee, Jonghyun; Jun, Dae Won; Song, Ildae; Kim, Yun

ArticleIssue Date2024CitationJournal of Cheminformatics, v.16, no.1, pp 1 - 12PublisherBMC
SCIESCOPUS
Editorial: Liver hypercortisolism as a potential target for MASH treatment—Authors' replyGo to Link

Kim, Yun; Hwang, Inyoung; Lee, Sang W.

ArticleIssue Date2023CitationAlimentary Pharmacology and Therapeutics, v.58, no.11-12, pp 1240 - 1241PublisherJohn Wiley and Sons Inc
SCIESCOPUS
Immune Landscape Changes in MASLD and the Effects of 11β-HSD1 Inhibition Revealed by Single-Cell Mass CytometryGo to Link

Gerelkhuu, Zayakhuu; Park, Sehee; Kim, Yun; Lee, Sang Won; Jun, Dae Won; Yoon, Tae Hyun

ArticleIssue Date2025CitationProteomics - Clinical Applications, v.19, no.5, pp 1 - 12PublisherWiley - VCH Verlag GmbH & CO. KGaA
SCIESCOPUS
Model-informed prediction of human pharmacokinetics and first-in-human dose selection of J2H-1702, a novel 11(3-hydroxysteroid dehydrogenase type 1 inhibitor for metabolic-associated steatohepatitisGo to Linkopen access

Kim, Inkyu; Hwang, Inyoung; Lee, Sang Won; Kim, Yun

ArticleIssue Date2026CitationEUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, v.219, pp 1 - 10PublisherELSEVIER
SCIESCOPUS
Multimodal Fusion-Based Lightweight Model for Enhanced Generalization in Drug-Target Interaction PredictionGo to Link

Lee, Jonghyun; Kim, Dokyoon; Jun, Dae Won; Kim, Yun

ArticleIssue Date2024CitationJournal of Chemical Information and Modeling, v.64, no.24, pp 9215 - 9226PublisherAmerican Chemical Society
SCIESCOPUS
Regulation of Hepatocyte Nuclear Factor 4α Attenuated Lipotoxicity but Increased Bile Acid Toxicity in Non-Alcoholic Fatty Liver DiseaseGo to Link

Roh, Yoon Jin; Kim, Yun; Lee, Jae Sun; Oh, Ju Hee; Lee, Seung Min; Yoon, Eileen Laurel; Lee, Sung Ryol; Jun, Dae Won

ArticleIssue Date2022CitationLife, v.12, no.11, pp.1 - 12PublisherMDPI AG
SCIESCOPUS
Safety, Pharmacokinetics, and Food Effect of the RORα Agonist TB-840, a Novel Candidate for Metabolic Dysfunction-Associated Steatohepatitis (MASH): A Randomized First-in-Human Study in Healthy VolunteersGo to Linkopen access

Hwang, Inyoung; Lee, Shi-Ra; Kim, Heung Jae; Kim, Yun; Lee, Sang Won

ArticleIssue Date2025CitationLife, v.15, no.9, pp 1 - 13PublisherMultidisciplinary Digital Publishing Institute (MDPI)
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