https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/336 2026-07-04T05:47:04Z 2026-07-04T05:47:04Z Kim, Ji Hong Kim, Yunjin Oraha, Kathy Michelle Park, Hae Min Kim, Yu Jeong Lim, Han Woong Sung, Yoon-Kyoung Welsbie, Derek S. Lee, Won June https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/213191 2026-06-10T01:00:16Z 2026-06-01T00:00:00Z

Title: Incidence of glaucoma in patients with systemic lupus erythematosus: a nationwide cohort study in South Korea Authors: Kim, Ji Hong; Kim, Yunjin; Oraha, Kathy Michelle; Park, Hae Min; Kim, Yu Jeong; Lim, Han Woong; Sung, Yoon-Kyoung; Welsbie, Derek S.; Lee, Won June Abstract: Background/aims To assess the incidence of glaucoma in patients with systemic lupus erythematosus (SLE) and to identify associated risk factors using a nationwide population-based cohort. Methods This retrospective cohort study analysed data from the Korean National Health Insurance Service (2008-2022). A total of 9682 patients with SLE were identified using ICD-10 code M32 and rare intractable disease code V136 and matched 1:1 to non-SLE controls by age and sex. The incidence of glaucoma (ICD-10 codes H40 and H42) and glaucoma suspect (H40.0) was assessed. Multivariate logistic regression was used to identify risk factors for glaucoma, including long-term corticosteroid use (>= 180 days). Results The incidence of glaucoma was significantly higher in the SLE group than in controls (11.34% vs 3.74%; p<0.0001), with a greater prevalence in younger patients (<40 years) and females. Glaucoma suspect cases were also more common in the SLE group (35.56% vs 30.25%; p<0.0001). SLE was independently associated with glaucoma (adjusted OR: 2.00, 95% CI 1.69 to 2.38), and prolonged corticosteroid use further increased the risk (OR: 1.75, 95% CI 1.51 to 2.02). Annual incidence trends showed a rising pattern over time, especially among SLE patients. Conclusions SLE is associated with an increased risk of glaucoma, particularly among younger individuals and females. Prolonged corticosteroid therapy significantly contributes to this risk. These findings support the need for regular ophthalmic screening and judicious corticosteroid management in patients with SLE.

2026-06-01T00:00:00Z Kim, Kyoung-woo Kim, Yu-jeong Jeon, Hyun-sun Choi, Young-joon Lee, Dongwoo Ross, Collin M. Lee, Hyung-keun Kim, Mee-kum https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/213259 2026-06-12T05:00:23Z 2026-05-01T00:00:00Z

Title: Trends and Characteristics of Corneal Transplantation in South Korea (2021–2023): A Three-Year Analysis of Domestic Survey and Eversight Eye Bank Data Authors: Kim, Kyoung-woo; Kim, Yu-jeong; Jeon, Hyun-sun; Choi, Young-joon; Lee, Dongwoo; Ross, Collin M.; Lee, Hyung-keun; Kim, Mee-kum Abstract: Purpose: To investigate current trends in corneal transplantation in South Korea by integrating data from the Korean Ophthalmological Society (KOS) and Eversight Eye Bank, focusing on surgical preferences, donor demographics, and evolving practices between 2021 and 2023. Methods: This retrospective epidemiological study reviewed data from annual KOS surveys of government-registered transplantation centers and records from the Eversight Eye Bank. Surgical categories included penetrating keratoplasty (PKP), anterior lamellar keratoplasty (ALK), Descemet’s stripping automated endothelial keratoplasty (DSAEK), Descemet’s membrane endothelial keratoplasty (DMEK), and keratolimbal allograft (KLA). Variables collected included types of surgery, donor demographics, sources of donor corneas, time from death to corneal preservation, and endothelial cell density (ECD). For endothelial keratoplasty (EK), additional graft-specific parameters were collected, including graft diameter, thickness, preloading status, and loading materials. Results: A total of 2636 corneal transplantations were identified. While PKP remained most commonly performed procedure (49.5% in 2023), the proportion of EK steadily increased. DMEK nearly doubled from 8.4% in 2021 to 15.2% in 2023. The proportion of imported donor tissue rose, reaching 74.5% by 2023. Donor age was significantly higher for DMEK (60.9 ± 6.0 years) than for PKP (48.0 ± 14.1 years) or DSAEK (50.7 ± 12.9 years). There was a clear trend toward greater use of preloaded grafts, smaller diameters, and novel loading techniques. Conclusion: Corneal transplantation in South Korea is shifting toward EK, especially DMEK, driven by limited domestic donations and changes in surgical preferences. These findings highlight the importance of enhancing local donation systems and maintaining robust data infrastructure to guide policy and clinical decision-making.

2026-05-01T00:00:00Z Lee, Yeon-Hee Sung, Jae Yun Shin, Sun Young Suh, Young-Woo Kim, Ungsoo Samuel Kim, Hyunkyung Park, Kyung-Ah Kim, Su Jin Kim, MiRae Shin, Hyun Jin Lee, Kyeong Wook Lee, Haeng-Jin Han, So Young Han, Jinu Hong, Eun Hee Baek, Seung-Hee Hannah Paik, Hae Jung Kim, Seung-Hyun Rhiu, Soolienah Lee, Joo Yeon Lim, Hyun Taek Jung, Jae Ho Choi, Hee-Young https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/212905 2026-06-01T01:30:25Z 2026-04-01T00:00:00Z

Title: Myopia Management Consensus Statement in South Korean Children 2025 by the Korean Myopia Society for the Korean Association for Pediatric Ophthalmology and Strabismus Authors: Lee, Yeon-Hee; Sung, Jae Yun; Shin, Sun Young; Suh, Young-Woo; Kim, Ungsoo Samuel; Kim, Hyunkyung; Park, Kyung-Ah; Kim, Su Jin; Kim, MiRae; Shin, Hyun Jin; Lee, Kyeong Wook; Lee, Haeng-Jin; Han, So Young; Han, Jinu; Hong, Eun Hee; Baek, Seung-Hee Hannah; Paik, Hae Jung; Kim, Seung-Hyun; Rhiu, Soolienah; Lee, Joo Yeon; Lim, Hyun Taek; Jung, Jae Ho; Choi, Hee-Young Abstract: Myopia, particularly high myopia, is a significant risk factor for several ocular pathologies including cataract, glaucoma, and retinal detachment. Excessive axial elongation associated with high myopia can induce biomechanical stretching, increasing the risk of serious complications like posterior staphyloma and myopic maculopathy. Global meta-analyses estimate that approximately 10 million people were visually impaired due to myopic maculopathy in 2015, with 3 million being blind. Recent nationwide surveys in South Korea revealed a prevalence of 65.4% for myopia and 6.9% for high myopia in children and adolescents, highlighting the urgent need for effective management. Delaying the onset and slowing the progression of myopia during childhood and adolescence is crucial for reducing the potential lifetime risk of these complications. This consensus statement, prepared by the Korean Myopia Society for the Korean Association for Pediatric Ophthalmology and Strabismus (KAPOS), reviews the current evidence for myopia control interventions and provides management strategies applicable to the South Korean clinical setting. Key interventions covered include lifestyle modifications (outdoor time, near work adjustment), optical methods (myopia-control spectacle lenses, dual-focus soft contact lenses, orthokeratology), and pharmacologic treatment (low-concentration atropine), as well as combination therapies. The statement also addresses patient selection, treatment outcome evaluation using spherical equivalent and axial length changes, and the crucial aspects related to treatment cessation and the rebound effect.

2026-04-01T00:00:00Z Kang, Jisoo Shin, Yong Un Kim, Ji Hong https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/213347 2026-06-18T01:00:17Z 2026-04-01T00:00:00Z

Title: Acute Vision Loss Following Intravitreal Ganciclovir Injection in Cytomegalovirus Retinitis: A Case Report Authors: Kang, Jisoo; Shin, Yong Un; Kim, Ji Hong Abstract: Purpose: We present a rare case of acute visual acuity loss following intravitreal ganciclovir injection for the treatment of cytomegalovirus (CMV) retinitis. Case summary: A 35-year-old woman receiving immunosuppressive therapy for systemic lupus erythematosus developed CMV retinitis in the left eye. Oral valganciclovir was initiated but discontinued due to cytopenia and treatment was switched to intravitreal ganciclovir injections (2 mg/0.04 mL). One year later, CMV retinitis developed in the right eye and the same regimen was initiated. Although receiving bilateral injections at two-week intervals, the patient experienced a sudden decrease in visual acuity in the right eye one day after injection, 10 months after treatment initiation. Optical coherence tomography and fluorescein angiography revealed inner retinal edema and focal macular leakage. Treatment was switched to intravenous foscarnet resulting in resolution of macular edema; however, central retinal thinning persisted. Owing to recurrent retinitis, intravitreal ganciclovir injections are currently being continued at a reduced dose (1 mg/0.02 mL). Conclusions: Acute visual acuity loss may rarely occur following intravitreal ganciclovir injection in patients with CMV retinitis. Careful consideration of potential mechanical injury and drug-induced retinal toxicity is needed during treatment.; 목적: 거대세포바이러스 망막염 치료를 위해 유리체강 내 간시클로버 주사 후 급성 시력 저하가 발생한 희귀 사례를 보고하고자 한다. 증례보고: 35세 여성은 전신성 홍반성 루푸스로 면역억제 치료 중 좌안에 거대세포바이러스 망막염이 발생하였고, 경구 발간시클로버 (valganciclovir)로 시작했으나 혈구감소증으로 유리체강 내 간시클로버(ganciclovir) 주사(2 mg/0.04 mL)로 변경하였다. 1년 후 우안 도 침범되어 동일한 치료를 시작했고, 양안에 2주 간격으로 주사 치료를 지속하던 중, 우안 치료 10개월째 주사 직후 급격한 시력 저하가 발생하였다. 빛간섭단층촬영 및 형광안저촬영에서 황반부 망막내층 부종과 국소 누출이 관찰되었으며, 이후 정맥 내 포스카넷 (foscarnet)으로 치료를 전환하였다. 황반부종은 호전되었으나 중심부 망막 위축이 잔존하였고, 이후 망막염이 재발하여 현재는 감량 된 용량(1 mg/0.02 mL)의 유리체강 내 간시클로버 주사로 치료를 유지하고 있다. 결론: 거대세포바이러스 망막염 환자에서 유리체강 내 간시클로버 주사 후 급성 시력 저하가 발생할 수 있으며, 기계적 손상이나 약물 독성 가능성을 고려한 주의 깊은 접근이 필요하다. <대한안과학회지 2026;67(4):131-136>

2026-04-01T00:00:00Z