https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/420 2026-07-04T12:55:31Z 2026-07-04T12:55:31Z Park, Kye-Yeung Han, Kyungdo Park, Jung Hwan Lee, Chang Beom Park, Hoon-Ki Hwang, Hwan-Sik Hong, Sangmo Yu, Sung Hoon https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/213900 2026-06-22T02:31:00Z 2026-06-01T00:00:00Z

Title: Waist-to-Height Ratio and the Risk of Cardiovascular Outcomes and Mortality in Type 2 Diabetes With and Without Abdominal Obesity Authors: Park, Kye-Yeung; Han, Kyungdo; Park, Jung Hwan; Lee, Chang Beom; Park, Hoon-Ki; Hwang, Hwan-Sik; Hong, Sangmo; Yu, Sung Hoon Abstract: Aim Waist-to-height ratio (WHtR) has been suggested as a superior marker of cardiometabolic risk compared to waist circumference (WC), but evidence in type 2 diabetes mellitus (T2DM) remains limited.Materials and Methods A population-based cohort of 2 076 104 patients with T2DM who underwent the Korean national health checkup between 2015 and 2016 were followed until 2022. Multivariable Cox proportional hazards regression was performed to analyse the association between WHtR and the risk of incident myocardial infarction, stroke and mortality. Restricted cubic spline analyses were performed to evaluate continuous dose-response relationships, with additional stratification by abdominal obesity.Results During follow-up, 125 493 deaths (6.0%), 56 280 myocardial infarctions (2.7%) and 62 938 strokes (3.0%) occurred. WHtR showed increasing association with the risk of myocardial infarction and stroke, and a U-shaped association with all-cause mortality. Individuals with both abdominal obesity and WHtR >= 0.5 had higher risks of myocardial infarction (HR 1.12, 95% CI 1.07-1.17), stroke (HR 1.18, 95% CI 1.15-1.21) and mortality (HR 1.20, 95% CI 1.16-1.25). In those without abdominal obesity, WHtR >= 0.5 was also associated with increased cardiovascular risks but slightly lower mortality. In contrast, those with abdominal obesity but normal WHtR had no significantly increased risks for any outcomes. The associations were stronger in younger adults and individuals with new-onset T2DM for cardiovascular outcomes, and in those with long-standing T2DM for mortality.Conclusions WHtR was independently associated with cardiovascular outcomes and mortality in individuals with T2DM, including those without abdominal obesity. This simple measurement may provide additional information beyond WC for evaluating cardiometabolic risk in this population.

2026-06-01T00:00:00Z Park, Kye-Yeung Lee, Kyu-na Hwang, Hwan-Sik Han, Kyungdo Park, Hoon-Ki https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/209132 2026-02-01T12:33:35Z 2025-11-01T00:00:00Z

Title: The risk of suicide mortality according to income dynamics assessed using health insurance premium data: A nationwide cohort study in Korea Authors: Park, Kye-Yeung; Lee, Kyu-na; Hwang, Hwan-Sik; Han, Kyungdo; Park, Hoon-Ki Abstract: Low income is a known risk factor for suicide; however, how changes in income and its fluctuation relate to suicide risk remains unexamined. Using the Korean National Health Insurance Service database, 4,031,867 adults aged 30 years or older who underwent a health checkup in 2012 were followed until the end of 2022. Based on health insurance premiums, income levels and changes between 2008 and 2012 were assessed. Low-income status was defined as the lowest quartile or receiving Medical Aid. Income variability was the standard deviation of the percentage change in income over five years. Hazard ratios (HRs) and 95 % confidence intervals (CIs) for suicide were calculated using multivariable Cox regression. During a 9.2-year follow-up, 10,012 suicide deaths (0.25 %) occurred. Persistent low income for five years was associated with a 48 % increased suicide risk (HR 1.48, 95 % CI 1.38-1.58) compared with those never in low income. Conversely, persistent high income was associated with a decreased suicide risk (HR 0.67, 95 % CI 0.64-0.71). Income decreases resulting in low-income status (HR 1.26, 95 % CI 1.12-1.43) and high variability in income (HR 1.37, 95 % CI 1.29-1.45) were also associated with increased suicide risk. These patterns were consistent regardless of the presence of depression and disability but were more pronounced in males and those under 65. In conclusion, persistent low-income, income decreases, and high variability were all independently associated with increased suicide risks. Suicide prevention strategies should promote income stability while accounting for age and sex.

2025-11-01T00:00:00Z Hong, Sangmo Han, Kyungdo Park, Kye-Yeung Lee, Chang Beom Kim, Dong Sun Park, Jung Hwan Yu, Sung Hoon https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/211744 2026-03-30T02:01:46Z 2025-11-01T00:00:00Z

Title: Association of Systolic and Diastolic Blood Pressure with the Risk of End-Stage Renal Disease in Older Type 2 Diabetes Mellitus Patients without Cardiovascular Disease: A Nationwide Population-Based Study Authors: Hong, Sangmo; Han, Kyungdo; Park, Kye-Yeung; Lee, Chang Beom; Kim, Dong Sun; Park, Jung Hwan; Yu, Sung Hoon Abstract: Background There is insufficient evidence to determine a precise blood pressure target in older adults with diabetes mellitus. In this study, we evaluated the potential relationship between blood pressure levels and end-stage renal disease (ESRD) in older type 2 diabetes mellitus (T2DM) patients without ESRD using a nationwide longitudinal population dataset. Methods We performed a retrospective, observational, cohort study including 267,156 older (≥65 years old) patients with T2DM and without ESRD from 2009 to 2018 based on the National Health Information Database. We divided the participants into eight groups based on their systolic blood pressure (SBP) and diastolic blood pressure (DBP). The primary outcome was ESRD. All outcomes were analyzed using Cox proportional hazards regression analysis while controlling for baseline covariates. Results During a median follow-up of 7.26 years, the incidence rate of ESRD was 2.03 per 1,000 person-years. In multivariable Cox proportional hazard modeling, the risk of the primary outcome was the lowest in groups with an SBP of 100–119 mm Hg and DBP of <80 mm Hg. In subgroup analysis according to the use of hypertension medication, there was a significant difference in DBP (P for interaction=0.026) but no difference in SBP (P for interaction=0.247). The risk of ESRD was the lowest in patients with an SBP of 110–129 mm Hg taking hypertension medication and the highest in the group with an SBP of ≥160 mm Hg. Conclusion Maintaining blood pressure at less than 120/80 mm Hg might prevent progression to ESRD in older T2DM patients without cardiovascular disease.

2025-11-01T00:00:00Z Cho, Sinyoung Jung, Jin-Hyung Nam, Ga Eun Cho, In Young Park, Kye-Yeung Jeong, Su-Min Han, Kyungdo https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/213115 2026-06-08T02:30:34Z 2025-10-01T00:00:00Z

Title: 2024 Obesity Fact Sheet in Korea: Prevalence of Obesity, Abdominal Obesity, Obesity Defined by Body Fat Percentage, and Underweight in Adults in Korea from 2013 to 2022 Authors: Cho, Sinyoung; Jung, Jin-Hyung; Nam, Ga Eun; Cho, In Young; Park, Kye-Yeung; Jeong, Su-Min; Han, Kyungdo Abstract: Background:The 2024 Obesity Fact Sheet provides an updated overview of the prevalence of obesity, abdominal obesity, underweight, and obesity as defined by body fat percentage and low muscle mass. Methods: This study included participants who underwent general health examinations provided by the tional Health Insurance Service between 2013 and 2022 (17,220,905 in 2022) and 4,425 participants in the Korea National Health and Nutrition Examination Survey (2022). Results: In 2022, prevalence rates of obesity and abdominal obesity were 38.4% (males 49.6%, females 27.7%) and 24.5% (males 31.3%, females 18.0%), respectively. Although the prevalence of obesity increased across classes, class II and III obesity increased notably by 1.6-fold and 2.6-fold, respectively, compared with 2013. prevalence of underweight was highest among adults aged 20 to 24 and those aged >= 85. Across all age groups, the prevalence of underweight was consistently higher among females than in males.The prevalence of obesity, defined as body fat percentage, was 41.5% (46.1% in males and 37.1% in females), whereas that of low muscle mass was 16.8%. Conclusion: This study presents updated data on the prevalence of obesity, abdominal obesity, underweight, and obesity defined by body fat percentage and low muscle mass. These findings highlight the need for timely strategies for obesity prevention and management, as well as the importance of addressing underweight status among young adults and older individuals. Moreover, our findings emphasize the complexity of obesity assessment, addressing the need for more detailed evaluation of body composition.

2025-10-01T00:00:00Z