https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/420 Fri, 24 Jul 2026 12:21:44 GMT 2026-07-24T12:21:44Z https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/213900 Title: Waist-to-Height Ratio and the Risk of Cardiovascular Outcomes and Mortality in Type 2 Diabetes With and Without Abdominal Obesity Authors: Park, Kye-Yeung; Han, Kyungdo; Park, Jung Hwan; Lee, Chang Beom; Park, Hoon-Ki; Hwang, Hwan-Sik; Hong, Sangmo; Yu, Sung Hoon Abstract: Aim Waist-to-height ratio (WHtR) has been suggested as a superior marker of cardiometabolic risk compared to waist circumference (WC), but evidence in type 2 diabetes mellitus (T2DM) remains limited.Materials and Methods A population-based cohort of 2 076 104 patients with T2DM who underwent the Korean national health checkup between 2015 and 2016 were followed until 2022. Multivariable Cox proportional hazards regression was performed to analyse the association between WHtR and the risk of incident myocardial infarction, stroke and mortality. Restricted cubic spline analyses were performed to evaluate continuous dose-response relationships, with additional stratification by abdominal obesity.Results During follow-up, 125 493 deaths (6.0%), 56 280 myocardial infarctions (2.7%) and 62 938 strokes (3.0%) occurred. WHtR showed increasing association with the risk of myocardial infarction and stroke, and a U-shaped association with all-cause mortality. Individuals with both abdominal obesity and WHtR >= 0.5 had higher risks of myocardial infarction (HR 1.12, 95% CI 1.07-1.17), stroke (HR 1.18, 95% CI 1.15-1.21) and mortality (HR 1.20, 95% CI 1.16-1.25). In those without abdominal obesity, WHtR >= 0.5 was also associated with increased cardiovascular risks but slightly lower mortality. In contrast, those with abdominal obesity but normal WHtR had no significantly increased risks for any outcomes. The associations were stronger in younger adults and individuals with new-onset T2DM for cardiovascular outcomes, and in those with long-standing T2DM for mortality.Conclusions WHtR was independently associated with cardiovascular outcomes and mortality in individuals with T2DM, including those without abdominal obesity. This simple measurement may provide additional information beyond WC for evaluating cardiometabolic risk in this population. Mon, 01 Jun 2026 00:00:00 GMT https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/213900 2026-06-01T00:00:00Z https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/218439 Title: 2025 Obesity Fact Sheet for Korea: Prevalence of Obesity, Abdominal Obesity from 2014 to 2023 and Prevalence of Chronic Disease by Obesity Status Authors: Kim, Esther; Cho, Sinyoung; Kim, Jiyoung; Kim, Bongseong; Seo, Ho-tak; Nam, Ga Eun; Cho, In Young; Park, Kye-Yeung; Jeong, Su-Min; Han, Kyungdo Abstract: Background: The 2025 obesity fact sheet provides an updated overview of the prevalence of obesity and abdominal obesity, as well as the prevalence of major chronic diseases according to obesity status in Korea. Methods: This study analyzed data from 17,576,389 adults who underwent general health examinations provided by the National Health Insurance Service from 2014 to 2023 and 17,660 participants from the Korean National Health and Nutrition Examination Survey (2019–2021). Results: In 2023, the prevalence of obesity and abdominal obesity was 38.4% (male 49.8%, female 27.5%) and 24.3% (male 31.3%, female 17.7%), respectively. Class II obesity was most prevalent among individuals aged 35–39 years (9.4%), and class III obesity peaked among those aged 30–34 years (2.6%). The prevalence of chronic diseases—including hypertension, diabetes mellitus, hypercholesterolemia, metabolic syndrome, and hyperuricemia—was 1.5- to 3.6-fold higher in individuals with obesity than in those without obesity, with particularly large differences in young adults and female. The prevalence of obstructive sleep apnea was 4.5-fold higher in the obese group, whereas osteoporosis was less common in the obese group than the non-obese group. Conclusion: The 2025 obesity fact sheet provides updated national data on obesity, abdominal obesity, and obesity-related chronic diseases in Korea, highlighting the substantial and persistent burden associated with obesity. These findings emphasize the urgent need for timely and effective strategies for obesity prevention and management. Copyright Wed, 01 Apr 2026 00:00:00 GMT https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/218439 2026-04-01T00:00:00Z https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/209132 Title: The risk of suicide mortality according to income dynamics assessed using health insurance premium data: A nationwide cohort study in Korea Authors: Park, Kye-Yeung; Lee, Kyu-na; Hwang, Hwan-Sik; Han, Kyungdo; Park, Hoon-Ki Abstract: Low income is a known risk factor for suicide; however, how changes in income and its fluctuation relate to suicide risk remains unexamined. Using the Korean National Health Insurance Service database, 4,031,867 adults aged 30 years or older who underwent a health checkup in 2012 were followed until the end of 2022. Based on health insurance premiums, income levels and changes between 2008 and 2012 were assessed. Low-income status was defined as the lowest quartile or receiving Medical Aid. Income variability was the standard deviation of the percentage change in income over five years. Hazard ratios (HRs) and 95 % confidence intervals (CIs) for suicide were calculated using multivariable Cox regression. During a 9.2-year follow-up, 10,012 suicide deaths (0.25 %) occurred. Persistent low income for five years was associated with a 48 % increased suicide risk (HR 1.48, 95 % CI 1.38-1.58) compared with those never in low income. Conversely, persistent high income was associated with a decreased suicide risk (HR 0.67, 95 % CI 0.64-0.71). Income decreases resulting in low-income status (HR 1.26, 95 % CI 1.12-1.43) and high variability in income (HR 1.37, 95 % CI 1.29-1.45) were also associated with increased suicide risk. These patterns were consistent regardless of the presence of depression and disability but were more pronounced in males and those under 65. In conclusion, persistent low-income, income decreases, and high variability were all independently associated with increased suicide risks. Suicide prevention strategies should promote income stability while accounting for age and sex. Sat, 01 Nov 2025 00:00:00 GMT https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/209132 2025-11-01T00:00:00Z https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/211744 Title: Association of Systolic and Diastolic Blood Pressure with the Risk of End-Stage Renal Disease in Older Type 2 Diabetes Mellitus Patients without Cardiovascular Disease: A Nationwide Population-Based Study Authors: Hong, Sangmo; Han, Kyungdo; Park, Kye-Yeung; Lee, Chang Beom; Kim, Dong Sun; Park, Jung Hwan; Yu, Sung Hoon Abstract: Background There is insufficient evidence to determine a precise blood pressure target in older adults with diabetes mellitus. In this study, we evaluated the potential relationship between blood pressure levels and end-stage renal disease (ESRD) in older type 2 diabetes mellitus (T2DM) patients without ESRD using a nationwide longitudinal population dataset. Methods We performed a retrospective, observational, cohort study including 267,156 older (≥65 years old) patients with T2DM and without ESRD from 2009 to 2018 based on the National Health Information Database. We divided the participants into eight groups based on their systolic blood pressure (SBP) and diastolic blood pressure (DBP). The primary outcome was ESRD. All outcomes were analyzed using Cox proportional hazards regression analysis while controlling for baseline covariates. Results During a median follow-up of 7.26 years, the incidence rate of ESRD was 2.03 per 1,000 person-years. In multivariable Cox proportional hazard modeling, the risk of the primary outcome was the lowest in groups with an SBP of 100–119 mm Hg and DBP of <80 mm Hg. In subgroup analysis according to the use of hypertension medication, there was a significant difference in DBP (P for interaction=0.026) but no difference in SBP (P for interaction=0.247). The risk of ESRD was the lowest in patients with an SBP of 110–129 mm Hg taking hypertension medication and the highest in the group with an SBP of ≥160 mm Hg. Conclusion Maintaining blood pressure at less than 120/80 mm Hg might prevent progression to ESRD in older T2DM patients without cardiovascular disease. Sat, 01 Nov 2025 00:00:00 GMT https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/211744 2025-11-01T00:00:00Z