Predicting long-term mortality with two different criteria of exercise-induced desaturation in COPD
DC Field | Value | Language |
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dc.contributor.author | Kim, Changhwan | - |
dc.contributor.author | Ko, Yousang | - |
dc.contributor.author | Lee, Jae Seung | - |
dc.contributor.author | Rhee, Chin Kook | - |
dc.contributor.author | Lee, Jin Hwa | - |
dc.contributor.author | Moon, Ji-Yong | - |
dc.contributor.author | Lim, Seong Yong | - |
dc.contributor.author | Yoo, Kwang Ha | - |
dc.contributor.author | Seo, Joon Beom | - |
dc.contributor.author | Oh, Yeon-Mok | - |
dc.contributor.author | Lee, Sang-Do | - |
dc.contributor.author | Park, Yong Bum | - |
dc.date.accessioned | 2021-07-30T04:43:19Z | - |
dc.date.available | 2021-07-30T04:43:19Z | - |
dc.date.created | 2021-07-14 | - |
dc.date.issued | 2021-06 | - |
dc.identifier.issn | 0954-6111 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/1055 | - |
dc.description.abstract | Background: There are few reports on exercise-induced desaturation (EID) as a predictor of mortality in chronic obstructive pulmonary disease (COPD). However, the definitions of EID vary in published reports. The main purpose was to evaluate the association between EID and long-term mortality by applying two criteria of EID. Methods: A total of 507 subjects were selected from the Korean Obstructive Lung Disease cohort. EID was assessed using the 6-min walk test (6MWT) and defined using two different criteria [1]: post-6MWT oxygen saturation (SpO(2)) of <= 88% (criterion A) and [2] post-6MWT SpO(2) < 90% or a decrease of >= 4% compared to baseline (criterion B). Results: The prevalence of EID was 5.1% based on criterion A and 13.0% based on criterion B. Regardless of the criteria used, mortality was higher in the EID group than in the non-EID group (A: 50 vs. 11.4%, B: 33.3 vs. 10.4%) during up to 161 months of follow-up. COPD patients without EID survived significantly longer than those with EID (A: 143.5 vs. 92.9, B: 144.8 vs. 115.2 months). Multivariate Cox regression analysis revealed that COPD patients with EID had a 2.4-fold increased risk of death by criterion A (adjusted HR 2.375; 95% CI: 1.217-4.637; P = 0.011). The risk of death increased in COPD patients with EID by criterion B, but the difference was not statistically significant. Conclusions: COPD patients with EID demonstrated significantly higher long-term mortality than those without EID. The EID criterion A has a better predictive value for mortality in COPD. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | W B SAUNDERS CO LTD | - |
dc.title | Predicting long-term mortality with two different criteria of exercise-induced desaturation in COPD | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Moon, Ji-Yong | - |
dc.identifier.doi | 10.1016/j.rmed.2021.106393 | - |
dc.identifier.scopusid | 2-s2.0-85104806046 | - |
dc.identifier.wosid | 000649753900012 | - |
dc.identifier.bibliographicCitation | RESPIRATORY MEDICINE, v.182, pp.1 - 7 | - |
dc.relation.isPartOf | RESPIRATORY MEDICINE | - |
dc.citation.title | RESPIRATORY MEDICINE | - |
dc.citation.volume | 182 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 7 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalResearchArea | Respiratory System | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.relation.journalWebOfScienceCategory | Respiratory System | - |
dc.subject.keywordPlus | 6-MIN WALK TEST | - |
dc.subject.keywordPlus | OBSTRUCTIVE PULMONARY-DISEASE | - |
dc.subject.keywordPlus | OXYGEN DESATURATION | - |
dc.subject.keywordPlus | EXERTIONAL DESATURATION | - |
dc.subject.keywordPlus | EMPHYSEMA | - |
dc.subject.keywordPlus | DISTANCE | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordAuthor | Chronic obstructive pulmonary disease | - |
dc.subject.keywordAuthor | Exercise-induced desaturation | - |
dc.subject.keywordAuthor | Mortality | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0954611121000998?via%3Dihub | - |
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