Magnetic resonance image-based tomotherapy planning for prostate canceropen access
- Authors
- Jung, Sang Hoon; Kim, Jinsung; Chung, Yoonsun; Keserci, Bilgin; Pyo, Hongryull; Park, Hee Chul; Park, Won
- Issue Date
- Mar-2020
- Publisher
- KOREAN SOC THERAPEUTIC RADIOLOGY & ONCOLOGY
- Keywords
- Prostatic neoplasms; Magnetic resonance imaging; Helical tomotherapy
- Citation
- RADIATION ONCOLOGY JOURNAL, v.38, no.1, pp.52 - 59
- Indexed
- SCOPUS
KCI
- Journal Title
- RADIATION ONCOLOGY JOURNAL
- Volume
- 38
- Number
- 1
- Start Page
- 52
- End Page
- 59
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/10619
- DOI
- 10.3857/roj.2020.00101
- ISSN
- 2234-1900
- Abstract
- Purpose: To evaluate and compare the feasibilities of magnetic resonance (MR) image-based planning using synthetic computed tomography (sCT) versus CT (pCT)-based planning in helical tomotherapy for prostate cancer. Materials and Methods: A retrospective evaluation was performed in 16 patients with prostate cancer who had been treated with helical tomotherapy. MR images were acquired using a dedicated therapy sequence; sCT images were generated using magnetic resonance for calculating attenuation (MRCAT). The three-dimensional dose distribution according to sCT was recalculated using a previously optimized plan and was compared with the doses calculated using pCT. Results: The mean planning target volume doses calculated by sCT and pCT differed by 0.65% +/- 1.11% (p = 0.03). Three-dimensional gamma analysis at a 2%/2 mm dose difference/distance to agreement yielded a pass rate of 0.976 (range, 0.658 to 0.986). Conclusion: The dose distribution results obtained using tomotherapy from MR-only simulations were in good agreement with the dose distribution results from simulation CT, with mean dose differences of less than 1% for target volume and normal organs in patients with prostate cancer.
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