Ratio of triglyceride to high-density lipoprotein cholesterol and risk of major cardiovascular events in kidney transplant recipients
DC Field | Value | Language |
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dc.contributor.author | Kim, Ji Eun | - |
dc.contributor.author | Yu, Mi-Yeon | - |
dc.contributor.author | Kim, Yong Chul | - |
dc.contributor.author | Min, Sang-il | - |
dc.contributor.author | Ha, Jongwon | - |
dc.contributor.author | Lee, Jung Pyo | - |
dc.contributor.author | Kim, Dong Ki | - |
dc.contributor.author | Oh, Kook-Hwan | - |
dc.contributor.author | Joo, Kwon-Wook | - |
dc.contributor.author | Ahn, Curie | - |
dc.contributor.author | Kim, Yon Su | - |
dc.contributor.author | Lee, Hajeong | - |
dc.date.accessioned | 2021-08-02T10:27:57Z | - |
dc.date.available | 2021-08-02T10:27:57Z | - |
dc.date.issued | 2019-12 | - |
dc.identifier.issn | 1342-1751 | - |
dc.identifier.issn | 1437-7799 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/11601 | - |
dc.description.abstract | Background Dyslipidemia is common in kidney transplant (KT) recipients. We analyzed the ratio of triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) in KT recipients to identify risk factors for major cardiovascular events (MACE). Methods We retrospectively included KT recipients with a lipid profile performed 1 year after transplantation. We classified patients according to the TG/HDL-C divided into quintiles. Subsequently, we analyzed the association between TG/HDL-C and MACE, defined as heart failure, coronary artery disease, and cerebrovascular disease confirmed by imaging studies. Results A total of 1301 KT recipients were enrolled. The median follow-up duration was 7.4 years (interquartile range 4.4–11.1 years). During the follow-up period, 80 (6.2%) patients developed MACE, which included 38 of unstable anginas, 9 of MIs, 19 of heart failures, 18 of cerebral infarcts, and 4 of cerebral hemorrhages. The fourth and fifth quintiles of TG/HDL-C showed a significantly increased risk of MACE [fourth quintile: adjusted hazard ratio (aHR), 3.38; 95% confidence interval (CI) 1.44–7.95; p = 0.005, fifth quintile: aHR, 2.67; 95% CI 1.13–6.30; p = 0.02]) compared to the second quintile of TG/HDL-C. This association is particularly evident in subgroups of non-DM, HTN, no history of CVD, and statin users. Conclusions Higher TG/HDL-C levels may be associated with MACE risk in KT recipients. | - |
dc.format.extent | 11 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | SPRINGER | - |
dc.title | Ratio of triglyceride to high-density lipoprotein cholesterol and risk of major cardiovascular events in kidney transplant recipients | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1007/s10157-019-01776-9 | - |
dc.identifier.scopusid | 2-s2.0-85071499077 | - |
dc.identifier.wosid | 000495765600008 | - |
dc.identifier.bibliographicCitation | CLINICAL AND EXPERIMENTAL NEPHROLOGY, v.23, no.12, pp 1407 - 1417 | - |
dc.citation.title | CLINICAL AND EXPERIMENTAL NEPHROLOGY | - |
dc.citation.volume | 23 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1407 | - |
dc.citation.endPage | 1417 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Urology & Nephrology | - |
dc.relation.journalWebOfScienceCategory | Urology & Nephrology | - |
dc.subject.keywordPlus | CORONARY-HEART-DISEASE | - |
dc.subject.keywordPlus | CARDIAC OUTCOMES | - |
dc.subject.keywordPlus | DYSLIPIDEMIA | - |
dc.subject.keywordPlus | INDIVIDUALS | - |
dc.subject.keywordPlus | FLUVASTATIN | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | PREVENTION | - |
dc.subject.keywordPlus | FAILURE | - |
dc.subject.keywordPlus | LIPIDS | - |
dc.subject.keywordPlus | DEATH | - |
dc.subject.keywordAuthor | Cholesterol | - |
dc.subject.keywordAuthor | Cardiovascular | - |
dc.subject.keywordAuthor | TG | - |
dc.subject.keywordAuthor | HDL-C | - |
dc.subject.keywordAuthor | Statins | - |
dc.subject.keywordAuthor | Kidney transplantation | - |
dc.identifier.url | https://link.springer.com/article/10.1007/s10157-019-01776-9 | - |
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