Patient-specific Hemodynamics of Severe Carotid Artery Stenosis Before and After Endarterectomy Examined by 4D Flow MRI
DC Field | Value | Language |
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dc.contributor.author | Ko, Seungbin | - |
dc.contributor.author | Lee, Jeesoo | - |
dc.contributor.author | Song, Simon | - |
dc.contributor.author | Kim, Doosang | - |
dc.contributor.author | Lee, Sang Hyung | - |
dc.contributor.author | Cho, Jee-Hyun | - |
dc.date.accessioned | 2021-08-02T10:28:17Z | - |
dc.date.available | 2021-08-02T10:28:17Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2019-12 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/11634 | - |
dc.description.abstract | Carotid endarterectomy (CEA) influences the carotid endoluminal anatomy, which results in hemodynamic changes before and after surgery. We investigated the hemodynamics of severe carotid artery stenosis before and after conventional endarterectomy with/without patch repair. An in vitro experiment utilizing carotid phantoms, which underwent a procedure that emulated CEA with/without the patch repair, was performed with a high-spatiotemporal resolution using 4D flow MRI. We evaluated an abnormal region of carotids, which consists of the normalized time-averaged wall shear stress (NTA vertical bar WSS vertical bar) and the oscillatory shear index (OSI), to account for continuous high-shear regions (high NTA vertical bar WSS vertical bar and low OSI) and chaotic low-shear regions, i.e., stenosis-prone regions (low NTA vertical bar WSS vertical bar and high OSI). The use of normalized hemodynamic parameters (e.g., NTA vertical bar WSS vertical bar) allowed comparison of diverse cases with different conditions of hemodynamics and vessel geometry. We observed that the stenosis-prone regions of the carotids with patches were noticeably larger than the corresponding regions in no-patch carotids. A large recirculating flow zone found in the stenosis-prone region of the internal carotid artery (ICA) of the postoperative carotids with patches partially blocks the flow path into ICA, and consequently the flow rate was not recovered after surgery unlike an expectation. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Nature Publishing Group | - |
dc.title | Patient-specific Hemodynamics of Severe Carotid Artery Stenosis Before and After Endarterectomy Examined by 4D Flow MRI | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Song, Simon | - |
dc.identifier.doi | 10.1038/s41598-019-54543-x | - |
dc.identifier.scopusid | 2-s2.0-85076268222 | - |
dc.identifier.wosid | 000501720800001 | - |
dc.identifier.bibliographicCitation | Scientific Reports, v.9 | - |
dc.relation.isPartOf | Scientific Reports | - |
dc.citation.title | Scientific Reports | - |
dc.citation.volume | 9 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | WALL SHEAR-STRESS | - |
dc.subject.keywordPlus | MAGNETIC-RESONANCE VELOCIMETRY | - |
dc.subject.keywordPlus | MEAN VELOCITY-MEASUREMENTS | - |
dc.subject.keywordPlus | BIFURCATION | - |
dc.subject.keywordPlus | ATHEROSCLEROSIS | - |
dc.subject.keywordPlus | REPRODUCIBILITY | - |
dc.subject.keywordPlus | GEOMETRY | - |
dc.subject.keywordPlus | LAYER | - |
dc.identifier.url | https://www.nature.com/articles/s41598-019-54543-x | - |
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