Effect of Muscle Cell Preservation on Viability and Differentiation of Hamstring Tendon Graft In Vitro
DC Field | Value | Language |
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dc.contributor.author | Lee, Jin Kyu | - |
dc.contributor.author | Jo, Sungsin | - |
dc.contributor.author | Lee, Young Lim | - |
dc.contributor.author | Weon, Subin | - |
dc.contributor.author | Song, Jun-Seob | - |
dc.contributor.author | Sung, Il-Hoon | - |
dc.contributor.author | Kim, Tae-Hwan | - |
dc.date.accessioned | 2021-07-30T04:45:10Z | - |
dc.date.available | 2021-07-30T04:45:10Z | - |
dc.date.created | 2021-07-14 | - |
dc.date.issued | 2021-04 | - |
dc.identifier.issn | 2073-4409 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/1266 | - |
dc.description.abstract | Muscle tissue is often removed during hamstring tendon graft preparation for anterior cruciate ligament (ACL) reconstruction. The purpose of the study was to test whether preservation of muscle remnants on a tendon graft is beneficial to the graft healing process following ACL reconstruction. Co-culturing of tendon-derived cells (TDCs) and muscle-derived cells (MDCs) was performed at various ratios, and their potential for cell viability and multilineage differentiation was compared to a single TDC cell group. Ligamentous and chondrogenic differentiation was most enhanced when a small population of MDCs was co-cultured with TDCs (6:2 co-culture group). Cell viability and osteogenic differentiation were proportionally enhanced with increasing MDC population size. MDCs co-cultured with TDCs possess both the ability to enhance cell viability and differentiate into other cell lineages. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.title | Effect of Muscle Cell Preservation on Viability and Differentiation of Hamstring Tendon Graft In Vitro | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Jin Kyu | - |
dc.contributor.affiliatedAuthor | Sung, Il-Hoon | - |
dc.contributor.affiliatedAuthor | Kim, Tae-Hwan | - |
dc.identifier.doi | 10.3390/cells10040740 | - |
dc.identifier.scopusid | 2-s2.0-85103862788 | - |
dc.identifier.wosid | 000642894900001 | - |
dc.identifier.bibliographicCitation | CELLS, v.10, no.4, pp.1 - 12 | - |
dc.relation.isPartOf | CELLS | - |
dc.citation.title | CELLS | - |
dc.citation.volume | 10 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 12 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cell Biology | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.subject.keywordAuthor | anterior cruciate ligament reconstruction | - |
dc.subject.keywordAuthor | tendon-derived cells | - |
dc.subject.keywordAuthor | muscle-derived cells | - |
dc.subject.keywordAuthor | multiple differentiation | - |
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