Glia/ischemia tissue dual specific gene expression vector for glioblastoma gene therapy
DC Field | Value | Language |
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dc.contributor.author | Kim, Hyun Ah | - |
dc.contributor.author | Park, Ji Hwan | - |
dc.contributor.author | Cho, Su Hee | - |
dc.contributor.author | Lee, Jiyoung | - |
dc.contributor.author | Lee, Minhyung | - |
dc.date.accessioned | 2022-04-01T10:03:27Z | - |
dc.date.available | 2022-04-01T10:03:27Z | - |
dc.date.created | 2022-01-24 | - |
dc.date.issued | 2011-09-14 | - |
dc.identifier.issn | 0168-3659 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/136543 | - |
dc.description.abstract | For glia/hypoxia dual specific gene expression, a dual specific expression vector was developed. pEpo-NI2-SV-Luc or pEpo-NI2-SV-was constructed with the nestin intron 2 (NI2)-SV40 promoter and erythropoietin (Epo) enhancer for glia cell and hypoxia specific gene expression. Gene expression by pEpo-NI2-SV-Luc was higher than pSV-Luc in glioblastoma cells under hypoxia. pEpo-NI2-SV-TK was constructed and transfected into C6 cells. The growth of the pEpo-NI2-SV-TK transfected cells was significantly suppressed in the presence of GCV. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Soochow University Biomedical Polymers Laboratory | - |
dc.title | Glia/ischemia tissue dual specific gene expression vector for glioblastoma gene therapy | - |
dc.type | Conference | - |
dc.contributor.affiliatedAuthor | Lee, Minhyung | - |
dc.identifier.scopusid | 2-s2.0-84861217137 | - |
dc.identifier.wosid | 000299125600099 | - |
dc.identifier.bibliographicCitation | 1st Symposium on Innovative Polymers for Controlled Delivery, pp.E146 - E148 | - |
dc.relation.isPartOf | 1st Symposium on Innovative Polymers for Controlled Delivery | - |
dc.relation.isPartOf | JOURNAL OF CONTROLLED RELEASE | - |
dc.citation.title | 1st Symposium on Innovative Polymers for Controlled Delivery | - |
dc.citation.startPage | E146 | - |
dc.citation.endPage | E148 | - |
dc.citation.conferencePlace | CC | - |
dc.citation.conferencePlace | Suzhou, PEOPLES R CHINA | - |
dc.citation.conferenceDate | 2010-09-14 | - |
dc.type.rims | CONF | - |
dc.description.journalClass | 1 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0168365911006675?via%3Dihub | - |
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