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Dexamethasone loaded r3v6 peptide micelles for gene delivery
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Lee, Jiyoung | - |
| dc.contributor.author | Hyun, Hyesun | - |
| dc.contributor.author | Kim, Hyun Ah | - |
| dc.contributor.author | Lee, Minhyung | - |
| dc.date.accessioned | 2022-04-01T10:03:39Z | - |
| dc.date.available | 2022-04-01T10:03:39Z | - |
| dc.date.created | 2022-01-24 | - |
| dc.date.issued | 2011-09-14 | - |
| dc.identifier.issn | 0168-3659 | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/136548 | - |
| dc.description.abstract | R3V6 peptides, which were composed of 3 arginines and 6 valines, formed self-assembled micelles in an aqueous solution. To improve the transfection efficiency of the R3V6 peptide micelles, a hydrophobic drug, dexamethasone was loaded into the core of the R3V6 peptide micelles. In vitro transfection assay showed that the dexamethasone-loaded R3V6 peptide micelles deliver DNA more effectively than the R3V6 micelles. In addition, the dexamethasone-loaded R3V6 micelles reduced the IL-6 levels in the lipopolysaccharide (LPS) activated macrophage cells. | - |
| dc.language | 영어 | - |
| dc.language.iso | en | - |
| dc.publisher | Soochow University Biomedical Polymers Laboratory | - |
| dc.title | Dexamethasone loaded r3v6 peptide micelles for gene delivery | - |
| dc.type | Conference | - |
| dc.contributor.affiliatedAuthor | Lee, Minhyung | - |
| dc.identifier.scopusid | 2-s2.0-84861203851 | - |
| dc.identifier.wosid | 000299125600102 | - |
| dc.identifier.bibliographicCitation | 1st Symposium on Innovative Polymers for Controlled Delivery, pp.E151 - E152 | - |
| dc.relation.isPartOf | 1st Symposium on Innovative Polymers for Controlled Delivery | - |
| dc.relation.isPartOf | JOURNAL OF CONTROLLED RELEASE | - |
| dc.citation.title | 1st Symposium on Innovative Polymers for Controlled Delivery | - |
| dc.citation.startPage | E151 | - |
| dc.citation.endPage | E152 | - |
| dc.citation.conferencePlace | CC | - |
| dc.citation.conferencePlace | Suzhou, PEOPLES R CHINA | - |
| dc.citation.conferenceDate | 2010-09-14 | - |
| dc.type.rims | CONF | - |
| dc.description.journalClass | 1 | - |
| dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0168365911006705?via%3Dihub | - |
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Related Researcher
- Lee, Min hyung
- COLLEGE OF ENGINEERING (DEPARTMENT OF BIOENGINEERING)