Impact of the estimated glomerular filtration rate on long-term mortality in patients with hypertensive crisis visiting the emergency department
DC Field | Value | Language |
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dc.contributor.author | Kim, Byung Sik | - |
dc.contributor.author | Yu, Mi-Yeon | - |
dc.contributor.author | Kim, Hyun-Jin | - |
dc.contributor.author | Lee, Jun Hyeok | - |
dc.contributor.author | Shin, Jeong-Hun | - |
dc.contributor.author | Shin, Jinho | - |
dc.date.accessioned | 2022-07-06T01:51:59Z | - |
dc.date.available | 2022-07-06T01:51:59Z | - |
dc.date.created | 2022-05-04 | - |
dc.date.issued | 2022-03 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/138383 | - |
dc.description.abstract | Background The association between renal function and all-cause mortality in patients with hypertensive crisis remains unclear. We aimed to identify the impact of estimated glomerular filtration rate (eGFR) on all-cause mortality in patients with hypertensive crisis visiting the emergency department (ED). Methods This retrospective study included patients aged ≥18 years admitted to the ED between 2016 and 2019 for hypertensive crisis (systolic blood pressure ≥180 mmHg and/or diastolic blood pressure ≥110 mmHg). They were classified into four groups according to the eGFR at admission to the ED: ≥90, 60–89, 30–59, and <30 mL/min/1.73 m2. Results Among the 4,821 patients, 46.7% and 5.8% had an eGFR of ≥90 and <30 mL/min/1.73 m2, respectively. Patients with lower eGFR were older and more likely to have comorbidities. The 3-year all-cause mortality rates were 7.7% and 41.9% in those with an eGFR ≥90 and <30 mL/min/1.73 m2, respectively. After adjusting for confounding variables, those with an eGFR of 30–59 (hazard ratio [HR], 1.93; 95% confidence interval [CI], 1.47–2.54) and <30 mL/min/1.73 m2 (HR, 2.35; 95% CI, 1.71–3.24) had significantly higher 3-year all-cause mortality risks than those with an eGFR of ≥90 mL/min/1.73 m2. Patients with an eGFR of 60–89 mL/min/1.73 m2 had a higher mortality (21.1%) than those with an eGFR of ≥90 mL/min/1.73 m2 (7.7%); however, the difference was not significant (HR, 1.21; 95% CI, 0.94–1.56). Conclusions Renal impairment is common in patients with hypertensive crisis who visit the ED. A strong independent association was observed between decreased eGFR and all-cause mortality in these patients. eGFR provides useful prognostic information and permits the early identification of patients with hypertensive crisis with an increased mortality risk. Intensive treatment and follow-up strategies are needed for patients with a decreased eGFR who visit the ED. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Public Library of Science | - |
dc.title | Impact of the estimated glomerular filtration rate on long-term mortality in patients with hypertensive crisis visiting the emergency department | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yu, Mi-Yeon | - |
dc.contributor.affiliatedAuthor | Kim, Hyun-Jin | - |
dc.contributor.affiliatedAuthor | Shin, Jeong-Hun | - |
dc.contributor.affiliatedAuthor | Shin, Jinho | - |
dc.identifier.doi | 10.1371/journal.pone.0266317 | - |
dc.identifier.scopusid | 2-s2.0-85127441243 | - |
dc.identifier.wosid | 000799828800092 | - |
dc.identifier.bibliographicCitation | PLoS ONE, v.17, no.3, pp.1 - 12 | - |
dc.relation.isPartOf | PLoS ONE | - |
dc.citation.title | PLoS ONE | - |
dc.citation.volume | 17 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 12 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | adult | - |
dc.subject.keywordPlus | Article | - |
dc.subject.keywordPlus | cause of death | - |
dc.subject.keywordPlus | comorbidity | - |
dc.subject.keywordPlus | controlled study | - |
dc.subject.keywordPlus | diastolic blood pressure | - |
dc.subject.keywordPlus | electronic medical record | - |
dc.subject.keywordPlus | emergency ward | - |
dc.subject.keywordPlus | estimated glomerular filtration rate | - |
dc.subject.keywordPlus | female | - |
dc.subject.keywordPlus | follow up | - |
dc.subject.keywordPlus | hazard ratio | - |
dc.subject.keywordPlus | hospital admission | - |
dc.subject.keywordPlus | hospitalization | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | hypertensive crisis | - |
dc.subject.keywordPlus | major clinical study | - |
dc.subject.keywordPlus | male | - |
dc.subject.keywordPlus | mortality | - |
dc.subject.keywordPlus | population research | - |
dc.subject.keywordPlus | retrospective study | - |
dc.subject.keywordPlus | risk factor | - |
dc.subject.keywordPlus | systolic blood pressure | - |
dc.subject.keywordPlus | trend study | - |
dc.subject.keywordPlus | adolescent | - |
dc.subject.keywordPlus | blood pressure | - |
dc.subject.keywordPlus | glomerulus filtration rate | - |
dc.subject.keywordPlus | hospital emergency service | - |
dc.subject.keywordPlus | physiology | - |
dc.subject.keywordPlus | risk assessment | - |
dc.identifier.url | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0266317 | - |
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