Clinical impact of left atrial enlargement in Korean patients with atrial fibrillation
DC Field | Value | Language |
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dc.contributor.author | Cho, Min Soo | - |
dc.contributor.author | Park, Hyoung-Seob | - |
dc.contributor.author | Cha, Myung-Jin | - |
dc.contributor.author | Lee, So-Ryoung | - |
dc.contributor.author | Park, Jin-Kyu | - |
dc.contributor.author | Kim, Tae-Hoon | - |
dc.contributor.author | Lee, Jung Myung | - |
dc.contributor.author | Park, Junbeom | - |
dc.contributor.author | Park, Hyung Wook | - |
dc.contributor.author | Kang, Ki-Woon | - |
dc.contributor.author | Shim, Jaemin | - |
dc.contributor.author | Uhm, Jae-Sun | - |
dc.contributor.author | Kim, Jin-Bae | - |
dc.contributor.author | Kim, Changsoo | - |
dc.contributor.author | Lee, Young Soo | - |
dc.contributor.author | Choi, Eue-Keun | - |
dc.contributor.author | Joung, Boyoung | - |
dc.contributor.author | Kim, Jun | - |
dc.date.accessioned | 2022-07-06T02:21:46Z | - |
dc.date.available | 2022-07-06T02:21:46Z | - |
dc.date.created | 2022-01-05 | - |
dc.date.issued | 2021-12 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/138587 | - |
dc.description.abstract | We sought to evaluate the clinical implication of LAE based on left atrial anterior-posterior (LA AP) dimension or LA volume index (LAVI) in Korean patients with atrial fibrillation (AF). We enrolled 8159 AF patients from the CODE-AF registry. The primary outcome was rate of stroke or systemic embolism (SSE). The prevalence of mild, moderate, and severe LAE by LA AP dimension was 30.6%, 18.5%, and 21.4%, and by LAVI (available in 5808 patients) was 15.7%, 12.5% and 37.8%, respectively. Compared with no or mild LAE, patients with significant LAE (moderate to severe LAE, n = 3258, 39.9%) were associated with a higher rate of SSE (2.5% vs. 1.4%, P = 0.001). Multivariable analysis suggested presence of significant LAE by LA AP dimension was associated with a higher risk of SSE in the overall population (HR 1.57, 95% CI: 1.14-2.17, P = 0.005) and in patients using anticoagulants (n = 5836, HR 1.79, 95% CI: 1.23-2.63, P = 0.002). Patients with significant LAE by LAVI were also at higher risk of SSE (HR 1.58, 95% CI: 1.09-2.29, P = 0.017). In conclusion, significant LAE by LA dimension or LAVI was present in 39.9% and 50.2% of AF patients, respectively, and was associated with a higher rate of SSE. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | NATURE PORTFOLIO | - |
dc.title | Clinical impact of left atrial enlargement in Korean patients with atrial fibrillation | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Jin-Kyu | - |
dc.identifier.doi | 10.1038/s41598-021-03266-z | - |
dc.identifier.scopusid | 2-s2.0-85120981728 | - |
dc.identifier.wosid | 000729143400045 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, v.11, no.1, pp.1 - 9 | - |
dc.relation.isPartOf | SCIENTIFIC REPORTS | - |
dc.citation.title | SCIENTIFIC REPORTS | - |
dc.citation.volume | 11 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 9 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | FOLLOW-UP | - |
dc.subject.keywordPlus | STROKE | - |
dc.subject.keywordPlus | RECURRENCE | - |
dc.subject.keywordPlus | SIZE | - |
dc.subject.keywordPlus | HYPERTENSION | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | GENDER | - |
dc.subject.keywordPlus | ADULTS | - |
dc.subject.keywordPlus | RHYTHM | - |
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