Attitudes toward Risk-Reducing Mastectomy and Risk-Reducing Salpingo-oophorectomy among Young, Unmarried, Healthy Women in Korea
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Boyoung | - |
dc.contributor.author | Kim, Dongwon | - |
dc.contributor.author | Kim, Jiyoung | - |
dc.contributor.author | Lee, Bom Yi | - |
dc.contributor.author | Yoon, Junghyun | - |
dc.contributor.author | Kim, Sung-Won | - |
dc.date.accessioned | 2022-07-06T06:25:03Z | - |
dc.date.available | 2022-07-06T06:25:03Z | - |
dc.date.created | 2022-05-04 | - |
dc.date.issued | 2022-04 | - |
dc.identifier.issn | 1598-2998 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/138978 | - |
dc.description.abstract | Purpose This study investigated the attitudes toward risk-reducing mastectomy (RRM) and risk-reducing salpingo-oophorectomy (RRSO) as cancer prevention options for BRCA1/2 carriers in healthy, young, unmarried Korean women. Materials and Methods A nationally representative sample of 600 women, aged 20–39 years, completed a questionnaire on sociodemographic variables, preference for genetic testing, and intention to undergo risk-reducing surgeries after receiving information on the cancer risk of BRCA1/2 mutations and benefits of risk-reducing surgeries. Results A total of 54.7% and 57.7% had the intention to undergo RRM and RRSO, respectively, on the assumption that they were BRCA1/2 carriers. Older age and no intention to undergo genetic testing were associated with a reduced likelihood of undergoing RRM (odds ratio [OR], 0.30; 95% confidence interval [CI], 0.14 to 0.61 for age 35–39 years and OR, 0.35; 95% CI, 0.20 to 0.62 for no intention for genetic testing) and RRSO (OR, 0.39; 95% CI, 0.19 to 0.79 for age 35–39 years and OR, 0.30; 95% CI, 0.17 to 0.53 for no intention for genetic testing). Women who chose to be single were likely to undergo risk-reducing surgeries (OR, 1.67; 95% CI, 1.07 to 2.60 for RRM and OR, 1.56; 95% CI, 1.00 to 2.44 for RRSO). Conclusion More than 50% of healthy, unmarried, young Korean women were inclined to undergo prophylactic surgeries if they were BRCA1/2 mutation carriers. Further studies on decision-making process for cancer prevention in individuals at high risk for cancer need to be conducted. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN CANCER ASSOCIATION | - |
dc.title | Attitudes toward Risk-Reducing Mastectomy and Risk-Reducing Salpingo-oophorectomy among Young, Unmarried, Healthy Women in Korea | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Boyoung | - |
dc.identifier.doi | 10.4143/crt.2021.449 | - |
dc.identifier.scopusid | 2-s2.0-85128493638 | - |
dc.identifier.wosid | 000789993400006 | - |
dc.identifier.bibliographicCitation | CANCER RESEARCH AND TREATMENT, v.54, no.2, pp.375 - 382 | - |
dc.relation.isPartOf | CANCER RESEARCH AND TREATMENT | - |
dc.citation.title | CANCER RESEARCH AND TREATMENT | - |
dc.citation.volume | 54 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 375 | - |
dc.citation.endPage | 382 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002830439 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.subject.keywordPlus | BREAST-CANCER RISK | - |
dc.subject.keywordPlus | PROPHYLACTIC MASTECTOMY | - |
dc.subject.keywordPlus | OVARIAN-CANCER | - |
dc.subject.keywordPlus | BRCA1/2 | - |
dc.subject.keywordPlus | PREVENTION | - |
dc.subject.keywordPlus | INTENTIONS | - |
dc.subject.keywordPlus | PERCEPTION | - |
dc.subject.keywordPlus | MUTATIONS | - |
dc.subject.keywordPlus | CARRIERS | - |
dc.subject.keywordPlus | SURGERY | - |
dc.subject.keywordAuthor | BRCA mutation | - |
dc.subject.keywordAuthor | Risk-reducing mastectomy | - |
dc.subject.keywordAuthor | Risk-reducing salpingo-oophorectomy | - |
dc.identifier.url | https://www.e-crt.org/journal/view.php?doi=10.4143/crt.2021.449 | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.