Neckband-Based Continuous Blood Pressure Monitoring Device with Offset-Tolerant ROIC

Abstract

This study presents a wearable neckband device for continuous cuffless blood pressure (BP) monitoring, where reliable neck-based BP measurement is achieved by utilizing the electrocardiogram (ECG) and impedance plethysmogram (IPG). Optimal composition and position of sensing electrodes around the neck were decided with consideration for physiological characteristics of the human body, and the core parameter of IPG magnitude was experimentally selected to improve the BP estimation accuracy. For its small-featured noises-tolerant detection capability, a customized readout integrated circuit (ROIC) was developed, which includes two kinds of analog front-ends (AFEs) for biopotential and bio-impedance. Both AFEs are proposed to include an attenuator-assisted hybrid DC-servo loop (DSL) structure, achieving precise pulse transit time (PTT) calculation by lowering the high-pass filtering cutoff frequency and also stable signal acquisition by widening the offset-cancellation range. Real-time PTT monitoring and BP estimation are wirelessly conducted, and its continuous operation time with 350-mAh battery capacity is longer than 5 hours. Efficacy of the proposed neckband BP device was evaluated for 8 healthy subjects under the physical stress condition, where the mean correlation coefficient and the standard deviation were achieved as 0.8508 and 4.17mmHg respectively.