Reduced acoustic resonator dimensions improve focusing efficiency of bacteria and submicron particles
DC Field | Value | Language |
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dc.contributor.author | Ugawa, Masashi | - |
dc.contributor.author | Lee, Hoyeon | - |
dc.contributor.author | Baasch, Thierry | - |
dc.contributor.author | Lee, Minho | - |
dc.contributor.author | Kim, Soyun | - |
dc.contributor.author | Jeong, OkChan | - |
dc.contributor.author | Choi, Yong-Hoon | - |
dc.contributor.author | Sohn, Daewon | - |
dc.contributor.author | Laurell, Thomas | - |
dc.contributor.author | Ota, Sadao | - |
dc.contributor.author | Lee, SangWook | - |
dc.date.accessioned | 2022-07-06T10:44:47Z | - |
dc.date.available | 2022-07-06T10:44:47Z | - |
dc.date.created | 2022-01-05 | - |
dc.date.issued | 2022-01 | - |
dc.identifier.issn | 0003-2654 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/139876 | - |
dc.description.abstract | In this study, we demonstrate an acoustofluidic device that enables single-file focusing of submicron particles and bacteria using a two-dimensional (2D) acoustic standing wave. The device consists of a 100 mu m x 100 mu m square channel that supports 2D particle focusing in the channel center at an actuation frequency of 7.39 MHz. This higher actuation frequency compared with conventional bulk acoustic systems enables radiation-force-dominant motion of submicron particles and overcomes the classical size limitation (approximate to 2 mu m) of acoustic focusing. We present acoustic radiation force-based focusing of particles with diameters less than 0.5 mu m at a flow rate of 12 mu L min(-1), and 1.33 mu m particles at flow rates up to 80 mu L min(-1). The device focused 0.25 mu m particles by the 2D acoustic radiation force while undergoing a channel cross-section centered, single-vortex acoustic streaming. A suspension of bacteria was also investigated to evaluate the biological relevance of the device, which demonstrated the alignment of bacteria in the channel at a flow rate of up to 20 mu L min(-1). The developed acoustofluidic device can align submicron particles within a narrow flow stream in a highly robust manner, validating its use as a flow-through focusing chamber to perform high-throughput and accurate flow cytometry of submicron objects. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.title | Reduced acoustic resonator dimensions improve focusing efficiency of bacteria and submicron particles | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Sohn, Daewon | - |
dc.identifier.doi | 10.1039/d1an01891d | - |
dc.identifier.scopusid | 2-s2.0-85123499152 | - |
dc.identifier.wosid | 000728662600001 | - |
dc.identifier.bibliographicCitation | ANALYST, v.147, no.2, pp.274 - 281 | - |
dc.relation.isPartOf | ANALYST | - |
dc.citation.title | ANALYST | - |
dc.citation.volume | 147 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 274 | - |
dc.citation.endPage | 281 | - |
dc.type.rims | ART | - |
dc.type.docType | Article; Early Access | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.subject.keywordPlus | FLOW-CYTOMETRY | - |
dc.subject.keywordPlus | CONTINUOUS SEPARATION | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | ACOUSTOPHORESIS | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | CHIP | - |
dc.identifier.url | https://pubs.rsc.org/en/content/articlelanding/2022/AN/D1AN01891D | - |
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