Interstitial lung disease increases susceptibility to and severity of COVID-19
DC Field | Value | Language |
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dc.contributor.author | Lee, Hyun | - |
dc.contributor.author | Choi, Hayoung | - |
dc.contributor.author | Yang, Bumhee | - |
dc.contributor.author | Lee, Sun-Kyung | - |
dc.contributor.author | Park, Tai Sun | - |
dc.contributor.author | Park, Dong Won | - |
dc.contributor.author | Moon, Ji-Yong | - |
dc.contributor.author | Kim, Tae-Hyung | - |
dc.contributor.author | Sohn, Jang Won | - |
dc.contributor.author | Yoon, Ho Joo | - |
dc.contributor.author | Kim, Sang-Heon | - |
dc.date.accessioned | 2022-07-06T11:12:29Z | - |
dc.date.available | 2022-07-06T11:12:29Z | - |
dc.date.created | 2021-07-15 | - |
dc.date.issued | 2021-12 | - |
dc.identifier.issn | 0903-1936 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/140281 | - |
dc.description.abstract | Background There are limited data regarding the relationship between interstitial lung disease (ILD) and the natural course of coronavirus disease 2019 (COVID-19). In this study, we investigate whether patients with ILD are more susceptible to COVID-19 than those without ILD and evaluate the impact of ILD on disease severity in patients with COVID-19. Methods A nationwide cohort of patients with COVID-19 (n=8070) and a 1:15 age-, sex-, and residence-matched cohort (n=121 050) were constructed between January 1, 2020 and May 30, 2020 in Korea. We performed a nested case-control study to compare the proportions of patients with ILD between the COVID-19 cohort and the matched cohort. Using the COVID-19 cohort, we also evaluated the risk of severe COVID-19 in patients with ILD versus those without ILD. Results The proportion of patients with ILD was significantly higher in the COVID-19 cohort than in the matched cohort (0.8% versus 0.4%, p<0.001). The odds ratio [OR] of having ILD was significantly higher in the COVID-19 cohort than in the matched cohort (adjusted OR=2.02, 95% confidence interval [CI]=1.54–2.61). Among patients in the COVID-19 cohort, patients with ILD were more likely to have severe COVID-19 than patients without ILD (49.3% versus 13.1%), including mortality (13.4% versus 2.8%) (all p<0.01). The risk of severe COVID-19 was significantly higher in patients with ILD than in those without ILD (adjusted OR=2.32, 95% CI=1.24–4.01). Conclusion The risks of COVID-19 and severe presentation were significantly higher in patients with ILD than in those without ILD. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | EUROPEAN RESPIRATORY SOC JOURNALS LTD | - |
dc.title | Interstitial lung disease increases susceptibility to and severity of COVID-19 | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Hyun | - |
dc.identifier.doi | 10.1183/13993003.04125-2020 | - |
dc.identifier.scopusid | 2-s2.0-85109075335 | - |
dc.identifier.wosid | 000728787900014 | - |
dc.identifier.bibliographicCitation | EUROPEAN RESPIRATORY JOURNAL, v.58, no.6, pp.1 - 10 | - |
dc.relation.isPartOf | EUROPEAN RESPIRATORY JOURNAL | - |
dc.citation.title | EUROPEAN RESPIRATORY JOURNAL | - |
dc.citation.volume | 58 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 10 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Respiratory System | - |
dc.relation.journalWebOfScienceCategory | Respiratory System | - |
dc.subject.keywordPlus | REGISTRY | - |
dc.subject.keywordAuthor | COVID 19 | - |
dc.subject.keywordAuthor | Epidemiology | - |
dc.subject.keywordAuthor | Interstitial lung disease | - |
dc.subject.keywordAuthor | Mortality | - |
dc.identifier.url | https://erj.ersjournals.com/content/58/6/2004125 | - |
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