The Entorhinal Cortex and Adult Neurogenesis in Major Depression
DC Field | Value | Language |
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dc.contributor.author | Kim, Il Bin | - |
dc.contributor.author | Park, Seon-Cheol | - |
dc.date.accessioned | 2022-07-06T11:41:36Z | - |
dc.date.available | 2022-07-06T11:41:36Z | - |
dc.date.created | 2021-12-08 | - |
dc.date.issued | 2021-11 | - |
dc.identifier.issn | 1661-6596 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/140519 | - |
dc.description.abstract | Depression is characterized by impairments in adult neurogenesis. Reduced hippocampal function, which is suggestive of neurogenesis impairments, is associated with depression-related phenotypes. As adult neurogenesis operates in an activity-dependent manner, disruption of hippocampal neurogenesis in depression may be a consequence of neural circuitry impairments. In particular, the entorhinal cortex is known to have a regulatory effect on the neural circuitry related to hippocampal function and adult neurogenesis. However, a comprehensive understanding of how disruption of the neural circuitry can lead to neurogenesis impairments in depression remains unclear with respect to the regulatory role of the entorhinal cortex. This review highlights recent findings suggesting neural circuitry-regulated neurogenesis, with a focus on the potential role of the entorhinal cortex in hippocampal neurogenesis in depression-related cognitive and emotional phenotypes. Taken together, these findings may provide a better understanding of the entorhinal cortex-regulated hippocampal neurogenesis model of depression. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.title | The Entorhinal Cortex and Adult Neurogenesis in Major Depression | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Seon-Cheol | - |
dc.identifier.doi | 10.3390/ijms222111725 | - |
dc.identifier.scopusid | 2-s2.0-85118143651 | - |
dc.identifier.wosid | 000719017000001 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.22, no.21, pp.1 - 16 | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
dc.citation.title | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
dc.citation.volume | 22 | - |
dc.citation.number | 21 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 16 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.subject.keywordPlus | DEEP-BRAIN-STIMULATION | - |
dc.subject.keywordPlus | TRANSCRANIAL MAGNETIC STIMULATION | - |
dc.subject.keywordPlus | VENTRAL CAPSULE/VENTRAL STRIATUM | - |
dc.subject.keywordPlus | DORSOLATERAL PREFRONTAL CORTEX | - |
dc.subject.keywordPlus | TREATMENT-RESISTANT DEPRESSION | - |
dc.subject.keywordPlus | ENHANCED SYNAPTIC PLASTICITY | - |
dc.subject.keywordPlus | ANTERIOR CINGULATE CORTEX | - |
dc.subject.keywordPlus | GENERATED GRANULE CELLS | - |
dc.subject.keywordPlus | HIPPOCAMPAL NEUROGENESIS | - |
dc.subject.keywordPlus | PATTERN SEPARATION | - |
dc.subject.keywordAuthor | depression | - |
dc.subject.keywordAuthor | entorhinal cortex | - |
dc.subject.keywordAuthor | hippocampus | - |
dc.subject.keywordAuthor | cognition | - |
dc.subject.keywordAuthor | emotion | - |
dc.subject.keywordAuthor | neural circuitry | - |
dc.subject.keywordAuthor | neurogenesis | - |
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