Computed Tomography-Determined Body Composition Abnormalities Usefully Predict Long-term Mortality in Patients with Liver Cirrhosis
DC Field | Value | Language |
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dc.contributor.author | Cho, Young Seo | - |
dc.contributor.author | Lee, Ha Young | - |
dc.contributor.author | Jeong, Jae Yoon | - |
dc.contributor.author | Lee, Jae Gon | - |
dc.contributor.author | Kim, Tae Yeob | - |
dc.contributor.author | Nam, Seong Woo | - |
dc.contributor.author | Sohn, Joo Hyun | - |
dc.date.accessioned | 2022-07-06T11:55:18Z | - |
dc.date.available | 2022-07-06T11:55:18Z | - |
dc.date.created | 2021-12-08 | - |
dc.date.issued | 2021-10 | - |
dc.identifier.issn | 0363-8715 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/140667 | - |
dc.description.abstract | Objective We evaluated the prognostic impacts of body composition components measured by computed tomography (CT) in patients with liver cirrhosis. Methods A total of 160 cirrhotic patients who underwent CT and hepatic venous pressure gradient measurements were retrospectively enrolled. Cross-sectional areas of skeletal muscle, visceral and subcutaneous fat, and mean CT attenuation of trabecular bone of the fourth lumbar vertebral level (L4HU) were measured. Results Multivariate analysis showed model for end-stage liver disease score [hazard ratio (HR), 1.086; 95% confidence interval (CI), 1.020-1.156; P = 0.010], hepatic venous pressure gradient (HR, 1.076; 95% CI, 1.021-1.135; P = 0.006), sarcopenia (HR, 1.890; 95% CI, 1.032-3.462; P = 0.039), and L4HU (HR, 1.960 for L4HU <145 Hounsfield units; 95% CI, 1.094-3.512; P = 0.024) were independently associated with long-term mortality. In patients with decompensated cirrhosis, subcutaneous adipose tissue index was the only independent predictor (HR, 0.984; 95% CI, 0.969-0.999; P = 0.039). Conclusion Body composition abnormalities determined by CT are associated with long-term prognosis in cirrhotic patients. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Lippincott Williams and Wilkins | - |
dc.title | Computed Tomography-Determined Body Composition Abnormalities Usefully Predict Long-term Mortality in Patients with Liver Cirrhosis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Sohn, Joo Hyun | - |
dc.identifier.doi | 10.1097/RCT.0000000000001207 | - |
dc.identifier.scopusid | 2-s2.0-85116193607 | - |
dc.identifier.wosid | 000698731700006 | - |
dc.identifier.bibliographicCitation | Journal of Computer Assisted Tomography, v.45, no.5, pp.684 - 690 | - |
dc.relation.isPartOf | Journal of Computer Assisted Tomography | - |
dc.citation.title | Journal of Computer Assisted Tomography | - |
dc.citation.volume | 45 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 684 | - |
dc.citation.endPage | 690 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | VENOUS-PRESSURE GRADIENT | - |
dc.subject.keywordPlus | BONE-MINERAL DENSITY | - |
dc.subject.keywordPlus | HEPATOCELLULAR-CARCINOMA | - |
dc.subject.keywordPlus | SARCOPENIA | - |
dc.subject.keywordPlus | OSTEOPOROSIS | - |
dc.subject.keywordPlus | DEPLETION | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordAuthor | liver cirrhosis | - |
dc.subject.keywordAuthor | body composition | - |
dc.subject.keywordAuthor | computed tomography | - |
dc.subject.keywordAuthor | prognosis | - |
dc.identifier.url | https://journals.lww.com/jcat/Fulltext/2021/09000/Computed_Tomography_Determined_Body_Composition.6.aspx | - |
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