Bariatric surgery versus medical therapy in Korean obese patients: prospective multicenter nonrandomized controlled trial (KOBESS trial)
DC Field | Value | Language |
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dc.contributor.author | Park, Do Joong | - |
dc.contributor.author | An, Sena | - |
dc.contributor.author | Park, Young Suk | - |
dc.contributor.author | Lee, Joo-Ho | - |
dc.contributor.author | Lee, Hyuk-Joon | - |
dc.contributor.author | Ha, Tae Kyung | - |
dc.contributor.author | Kim, Yong-Jin | - |
dc.contributor.author | Ryu, Seung-Wan | - |
dc.contributor.author | Han, Sang-Moon | - |
dc.contributor.author | Yoo, Moon-Won | - |
dc.contributor.author | Park, Sungsoo | - |
dc.contributor.author | Han, Sang-Uk | - |
dc.contributor.author | Kang, Jae-Heon | - |
dc.contributor.author | Kwon, Jin-Won | - |
dc.contributor.author | Heo, Yoonseok | - |
dc.date.accessioned | 2022-07-06T12:00:46Z | - |
dc.date.available | 2022-07-06T12:00:46Z | - |
dc.date.created | 2021-12-08 | - |
dc.date.issued | 2021-10 | - |
dc.identifier.issn | 2288-6575 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/140771 | - |
dc.description.abstract | Purpose: The aim of this study was to show that bariatric surgery (BS) is more effective than medical therapy (MT) in Asian obese patients. Methods: In this prospective, multicenter, nonrandomized, controlled trial, obese patients with body mass index of >= 35 kg/m(2) or 30.0-34.9 kg/m(2) with obesity-related comorbidities were assigned to undergo BS, such as laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass, or MT. Patients who underwent BS were evaluated 4, 12, 24, and 48 weeks after surgery, whereas patients who received MT were monitored at a hospital every 6 weeks for 1 year. At each visit, weight, waist and hip circumference, and blood pressure were measured, and patients underwent physical examination and laboratory testing. Health-related quality of life (HQOL) was investigated using Euro QOL-5 Dimension, Impact of Weight on Quality of Life questionnaire-Lite and Obesity-related Problems scale. Results: The study included 264 patients from 13 institutions; of these, 64 underwent BS and 200 received MT. Of the patients who underwent BS, 6.3% experienced early complications. Relative weight changes from baseline to 48 weeks were significantly greater in the BS than in the MT group (26.9% vs. 2.1%, P < 0.001), as were the rates of remission of diabetes (47.8% vs. 16.7%, P = 0.014), hypertension (60.0% vs. 26.1%, P < 0.001), and dyslipidemia (63.2% vs. 22.0%, P < 0.001). HQOL was better in the BS than in the MT group at 48 weeks. Conclusion: BS was safe and effective in Korean obese patients, with greater weight reduction, remission of comorbidities, and quality of life improvement than MT. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SURGICAL SOCIETY | - |
dc.title | Bariatric surgery versus medical therapy in Korean obese patients: prospective multicenter nonrandomized controlled trial (KOBESS trial) | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Ha, Tae Kyung | - |
dc.identifier.doi | 10.4174/astr.2021.101.4.197 | - |
dc.identifier.scopusid | 2-s2.0-85117037857 | - |
dc.identifier.wosid | 000708407600001 | - |
dc.identifier.bibliographicCitation | ANNALS OF SURGICAL TREATMENT AND RESEARCH, v.101, no.4, pp.197 - 205 | - |
dc.relation.isPartOf | ANNALS OF SURGICAL TREATMENT AND RESEARCH | - |
dc.citation.title | ANNALS OF SURGICAL TREATMENT AND RESEARCH | - |
dc.citation.volume | 101 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 197 | - |
dc.citation.endPage | 205 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002760690 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | LAPAROSCOPIC-SLEEVE-GASTRECTOMY | - |
dc.subject.keywordPlus | QUALITY-OF-LIFE | - |
dc.subject.keywordPlus | CONVENTIONAL THERAPY | - |
dc.subject.keywordPlus | GASTRIC BYPASS | - |
dc.subject.keywordPlus | SUBJECTS SOS | - |
dc.subject.keywordPlus | HEALTH | - |
dc.subject.keywordPlus | HISTORY | - |
dc.subject.keywordPlus | INTERVENTION | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordAuthor | Asia | - |
dc.subject.keywordAuthor | Bariatric surgery | - |
dc.subject.keywordAuthor | Metabolic diseases | - |
dc.subject.keywordAuthor | Obesity | - |
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