Experimental Demonstration of a Stacked Hybrid Optoacoustic-Piezoelectric Transducer for Localized Heating and Enhanced Cavitation
DC Field | Value | Language |
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dc.contributor.author | Sang, Pil Gyu | - |
dc.contributor.author | Biswas, Deblina | - |
dc.contributor.author | Lee, Seung Jin | - |
dc.contributor.author | Won, Sang Min | - |
dc.contributor.author | Son, Donghee | - |
dc.contributor.author | Ok, Jong G. | - |
dc.contributor.author | Park, Hui Joon | - |
dc.contributor.author | Baac, Hyoung Won | - |
dc.date.accessioned | 2022-07-06T12:03:27Z | - |
dc.date.available | 2022-07-06T12:03:27Z | - |
dc.date.created | 2021-12-08 | - |
dc.date.issued | 2021-10 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/140807 | - |
dc.description.abstract | Laser-generated focused ultrasound (LGFU) is an emerging modality for cavitation-based therapy. However, focal pressure amplitudes by LGFU alone to achieve pulsed cavitation are often lacking as a treatment depth increases. This requires a higher pressure from a transmitter surface and more laser energies that even approach to a damage threshold of transmitter. To mitigate the requirement for LGFU-induced cavitation, we propose LGFU configurations with a locally heated focal zone using an additional high-intensity focused ultrasound (HIFU) transmitter. After confirming heat-induced cavitation enhancement using two separate transmitters, we then developed a stacked hybrid optoacoustic-piezoelectric transmitter, which is a unique configuration made by coating an optoacoustic layer directly onto a piezoelectric substrate. This shared curvature design has great practical advantage without requiring the complex alignment of two focal zones. Moreover, this enabled the amplification of cavitation bubble density by 18.5-fold compared to the LGFU operation alone. Finally, the feasibility of tissue fragmentation was confirmed through a tissue-mimicking gel, using the combination of LGFU and HIFU (not via a stacked structure). We expect that the stacked transmitter can be effectively used for stronger and faster tissue fragmentation than the LGFU transmitter alone. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.title | Experimental Demonstration of a Stacked Hybrid Optoacoustic-Piezoelectric Transducer for Localized Heating and Enhanced Cavitation | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Hui Joon | - |
dc.identifier.doi | 10.3390/mi12101268 | - |
dc.identifier.scopusid | 2-s2.0-85118190615 | - |
dc.identifier.wosid | 000713643200001 | - |
dc.identifier.bibliographicCitation | MICROMACHINES, v.12, no.10, pp.1 - 11 | - |
dc.relation.isPartOf | MICROMACHINES | - |
dc.citation.title | MICROMACHINES | - |
dc.citation.volume | 12 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 11 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.subject.keywordPlus | GENERATED-FOCUSED ULTRASOUND | - |
dc.subject.keywordPlus | FIBEROPTIC HYDROPHONE | - |
dc.subject.keywordPlus | DELIVERY | - |
dc.subject.keywordPlus | COST | - |
dc.subject.keywordAuthor | laser-generated focused ultrasound | - |
dc.subject.keywordAuthor | pulsed cavitation | - |
dc.subject.keywordAuthor | tissue therapy | - |
dc.subject.keywordAuthor | precision therapy | - |
dc.identifier.url | https://www.mdpi.com/2072-666X/12/10/1268 | - |
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