Mechanical bowel preparation combined with oral antibiotics in colorectal cancer surgery: a nationwide population-based study
- Authors
- Lee, Jun Ho; Ahn, Byung Kyu; Ryu, Jiin; Lee, Kang Hong
- Issue Date
- Sep-2021
- Publisher
- SPRINGER
- Keywords
- Surgical site infection; Oral antibiotics; Mechanical bowel preparation; Colorectal surgery
- Citation
- INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, v.36, no.9, pp.1929 - 1935
- Indexed
- SCIE
SCOPUS
- Journal Title
- INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
- Volume
- 36
- Number
- 9
- Start Page
- 1929
- End Page
- 1935
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/141199
- DOI
- 10.1007/s00384-021-03967-x
- ISSN
- 0179-1958
- Abstract
- Background
The guidelines for reducing surgical site infection in colorectal surgery recommend mechanical bowel preparation with oral antibiotics; however, this recommendation remains controversial. This study aimed to reveal the effect of oral antibiotics combined with mechanical bowel preparation in colorectal surgery.
Methods
This study was a nationwide population-based retrospective study. Data between January 1, 2016, and December 31, 2018, from the Korean National Health Insurance Service database were analyzed. Patients who underwent elective colorectal cancer surgery were included.
Results
A total of 20,740 patients were finally included, comprising 14,554 (70.2%) who underwent mechanical bowel preparation alone and 6186 (29.8%) who underwent mechanical bowel preparation with oral antibiotics. The mechanical bowel preparation alone group was older than the mechanical bowel preparation with oral antibiotics group (65.7 ± 11.9 vs. 64.7 ± 11.8 years, p < 0.001). Rectal cancer patients and patients who underwent open surgery were more likely to receive mechanical bowel preparation with oral antibiotics. Patients who underwent mechanical bowel preparation with oral antibiotics demonstrated lower surgical-site infection rate (2.9% vs. 9.4%, p < 0.001), shorter hospital stay (11.7 ± 5.5 vs. 13.5 ± 7.3 days, p < 0.001), and lower medical cost (US$7414 ± 2762 vs. US$7791 ± 3235, p < 0.001) than those who underwent mechanical bowel preparation alone. The 30-day readmission rates and mortality were not significantly different.
Conclusions
The use of mechanical bowel preparation with oral antibiotics reduces surgical site infection, hospital stay, and medical cost in colorectal cancer surgery.
- Files in This Item
-
Go to Link
- Appears in
Collections - 서울 의과대학 > 서울 외과학교실 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/141199)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.