Rate of central corneal thickness changes in primary angle closure eyes: long-term follow-up results
DC Field | Value | Language |
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dc.contributor.author | Park, Hae Min | - |
dc.contributor.author | Choi, Jiin | - |
dc.contributor.author | Lee, Won June | - |
dc.contributor.author | Uhm, Ki Bang | - |
dc.date.accessioned | 2022-07-07T00:30:56Z | - |
dc.date.available | 2022-07-07T00:30:56Z | - |
dc.date.created | 2021-07-14 | - |
dc.date.issued | 2021-03 | - |
dc.identifier.issn | 1471-2415 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/142190 | - |
dc.description.abstract | Background Central corneal thickness (CCT) and its association with intraocular pressure, which is a pivotal parameter in glaucoma management, has previously been reported. In this study, we intended to investigate the long-term change of CCT in terms of rate in eyes with primary angle-closure (PAC). Additionally, we aimed to analyze events that could affect CCT. Methods In this retrospective study, 26 patients with PAC who had a follow-up period of more than 5 years were analyzed. The rate of CCT changes from baseline was evaluated from the serial CCT measurements over the average follow-up period. The pattern of CCT change rate according to modes of treatment and history of angle-closure attack was analyzed using the repeated linear mixed model analysis. Results A total of 52 eyes were enrolled. The CCT reduction rate of the entire study population was − 0.72 ± 0.22 μm/yr (P = 0.001) with statistical significance. The CCT thinning rate of the laser peripheral iridotomy (PI) group was − 0.53 ± 0.25 μm/yr (P = 0.034) and that of the surgical trabeculectomy group was − 1.32 ± 0.43 μm/yr (P = 0.002), and it was not statistically significant (P = 0.112). The rate of CCT thinning in patients with a history of acute angle-closure attack was − 0.81 ± 0.31 μm/yr (P = 0.009) and that in patients without an attack was − 0.63 ± 0.30 μm/yr (P = 0.001), and it was not statistically significant (P = 0.680). Baseline CCT appeared to be the only significant factor affecting the rate of CCT changes (P < 0.001). Conclusions We found a significant reduction in CCT over a long observation period in PAC eyes. We also found that the rates of CCT reduction were not affected by different treatment modalities or acute angle-closure attacks. The analysis of long-term CCT changes in conjunction with baseline CCT would also be helpful in the clinical evaluation of the PAC patients. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | BMC | - |
dc.title | Rate of central corneal thickness changes in primary angle closure eyes: long-term follow-up results | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Won June | - |
dc.identifier.doi | 10.1186/s12886-021-01908-4 | - |
dc.identifier.scopusid | 2-s2.0-85103085860 | - |
dc.identifier.wosid | 000632828500002 | - |
dc.identifier.bibliographicCitation | BMC OPHTHALMOLOGY, v.21, no.1, pp.1 - 10 | - |
dc.relation.isPartOf | BMC OPHTHALMOLOGY | - |
dc.citation.title | BMC OPHTHALMOLOGY | - |
dc.citation.volume | 21 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 10 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Ophthalmology | - |
dc.relation.journalWebOfScienceCategory | Ophthalmology | - |
dc.subject.keywordPlus | MANIFEST GLAUCOMA TRIAL | - |
dc.subject.keywordPlus | NORMAL-TENSION GLAUCOMA | - |
dc.subject.keywordPlus | INTRAOCULAR-PRESSURE | - |
dc.subject.keywordPlus | OCULAR HYPERTENSION | - |
dc.subject.keywordPlus | RISK-FACTOR | - |
dc.subject.keywordPlus | HYSTERESIS | - |
dc.subject.keywordPlus | PARAMETERS | - |
dc.subject.keywordPlus | CHINESE | - |
dc.subject.keywordPlus | LATANOPROST | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordAuthor | Glaucoma | - |
dc.subject.keywordAuthor | Central corneal thickness | - |
dc.subject.keywordAuthor | Corneal biomechanics | - |
dc.subject.keywordAuthor | Primary angle-closure | - |
dc.subject.keywordAuthor | Glaucoma management | - |
dc.identifier.url | https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12886-021-01908-4 | - |
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