Is There Pathological Uniformity between the Periphery and Center of a Gastrointestinal Stromal Tumor?
DC Field | Value | Language |
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dc.contributor.author | Choi, Seong Ji | - |
dc.contributor.author | Lee, Kwan Hong | - |
dc.contributor.author | Yoo, Chan Kyoo | - |
dc.contributor.author | Yoon, Jai Hoon | - |
dc.contributor.author | Jang, Ki Seok | - |
dc.contributor.author | Kim, Youn Jeong | - |
dc.contributor.author | Lee, Hang Lak | - |
dc.date.accessioned | 2022-07-07T00:54:53Z | - |
dc.date.available | 2022-07-07T00:54:53Z | - |
dc.date.created | 2021-07-14 | - |
dc.date.issued | 2021-02 | - |
dc.identifier.issn | 2077-0383 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/142302 | - |
dc.description.abstract | Background: Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors and have some malignant potential. Mitotic count is important for predicting the malignant potential of GISTs. Proper treatment of GISTs requires accurate pathological diagnosis. In general, endoscopic ultrasound-guided fine-needle aspiration and deep biopsy are used for pathological diagnosis of GIST before making decisions about surgery. This study sought to evaluate the pathological uniformity of gastric GISTs for mitotic index of the center and periphery of the GIST. Methods: We retrospectively reviewed the data of 37 gastric GIST patients who underwent wedge resection at Hanyang University Hospital. We used Armed Forces Institute of Pathology criteria to classify gastric GISTs. To determine the pathological uniformity of gastric GISTs, we compared GIST risk stratification between the center and periphery of GISTs. Results: The mean size of GISTs was 3.56 ± 2.10 cm. Three lesions were located in the antrum, 11 in the fundus, 9 in the cardia, and 14 in the body. The mean age of patients was 58.65 ± 9.44 years; 18 patients were male and 19 were female. Thirty-five patients (94.6%) showed the same level of risk stratification between the center and periphery of gastric GISTs, while two patients (5.4%) presented different levels of risk between the two sites. No significant difference in mitotic count was observed between the two sites (kappa value = 0.863; p = 0.001). Conclusions: Mitotic index category (either more than five mitoses per high-power field or five or fewer mitoses per high-power field) of GISTs showed good concurrence between the center and periphery. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.title | Is There Pathological Uniformity between the Periphery and Center of a Gastrointestinal Stromal Tumor? | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yoon, Jai Hoon | - |
dc.contributor.affiliatedAuthor | Jang, Ki Seok | - |
dc.contributor.affiliatedAuthor | Lee, Hang Lak | - |
dc.identifier.doi | 10.3390/jcm10040687 | - |
dc.identifier.scopusid | 2-s2.0-85114080442 | - |
dc.identifier.wosid | 000624073800001 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL MEDICINE, v.10, no.4, pp.1 - 10 | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL MEDICINE | - |
dc.citation.title | JOURNAL OF CLINICAL MEDICINE | - |
dc.citation.volume | 10 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 10 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | CD34 antigen | - |
dc.subject.keywordPlus | desmin | - |
dc.subject.keywordPlus | protein S 100 | - |
dc.subject.keywordPlus | smooth muscle actin | - |
dc.subject.keywordPlus | abdominal discomfort | - |
dc.subject.keywordPlus | adult | - |
dc.subject.keywordPlus | aged | - |
dc.subject.keywordPlus | anorexia | - |
dc.subject.keywordPlus | Article | - |
dc.subject.keywordPlus | cardia | - |
dc.subject.keywordPlus | clinical article | - |
dc.subject.keywordPlus | clinical feature | - |
dc.subject.keywordPlus | controlled study | - |
dc.subject.keywordPlus | data analysis software | - |
dc.subject.keywordPlus | endoscopic ultrasonography | - |
dc.subject.keywordPlus | female | - |
dc.subject.keywordPlus | gastrointestinal hemorrhage | - |
dc.subject.keywordPlus | gastrointestinal stromal tumor | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | human tissue | - |
dc.subject.keywordPlus | male | - |
dc.subject.keywordPlus | mitosis index | - |
dc.subject.keywordPlus | nausea | - |
dc.subject.keywordPlus | protein expression | - |
dc.subject.keywordPlus | recurrent disease | - |
dc.subject.keywordPlus | retrospective study | - |
dc.subject.keywordPlus | risk assessment | - |
dc.subject.keywordPlus | stomach antrum | - |
dc.subject.keywordPlus | stomach corpus | - |
dc.subject.keywordPlus | stomach fundus | - |
dc.subject.keywordPlus | tumor volume | - |
dc.subject.keywordPlus | wedge resection | - |
dc.subject.keywordAuthor | gastric gastrointestinal stromal tumors | - |
dc.subject.keywordAuthor | mitotic count | - |
dc.subject.keywordAuthor | pathological uniformity | - |
dc.identifier.url | https://www.mdpi.com/2077-0383/10/4/687 | - |
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