신혈관근지방종의 치료로 시행한 선택적동맥색전술의 장기간 치료 효과 분석

Abstract

Purpose: We evaluate the complication rates and the treatment outcome of patients treated by selective arterial embolization (SAE) for a large or symptomatic renal angiomyolipoma (AML). Materials and Methods: 52 patients with 56 kidneys containing AML were treated by SAE. All patients were treated by SAE and followed up in multicenter. The variables used for the analysis were age, gender, presence of tuberous sclerosis (TS), and maximal tumor size prior to SAE. The study end points were recurrence of symptoms or bleeding, the need for re-embolization or surgery, and disease-specific survival. The mean follow-up period for the entire group was 6.8 year. Results: Mean patient age was 51.4 year and the mean initial tumor size was 8.8cm. Successful SAE was achieved in 48 cases (84.8%) with minor complication rate of 11.5%. Avoidance of surgery was achieved in 91.9% of the kidneys in five years. And avoidance of re-embolization was achieved in 67.9% in five years. No retroperitoneal hemorrhage was noted during follow-up. Disease-specific survival of the entire cohort was 100%. Conclusions: SAE of renal AML has long-term efficacy in preventing hemorrhagic complications of renal AML, and preservation of the involved kidneys is amenable.