Development of a Paper-Based Viscometer for Blood Plasma Using Colorimetric Analysis
DC Field | Value | Language |
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dc.contributor.author | Kang, Hyunwoong | - |
dc.contributor.author | Jang, Ilhoon | - |
dc.contributor.author | Song, Simon | - |
dc.contributor.author | Bae, Sang-Cheol | - |
dc.date.accessioned | 2021-08-02T11:53:48Z | - |
dc.date.available | 2021-08-02T11:53:48Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2019-04 | - |
dc.identifier.issn | 0003-2700 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/14273 | - |
dc.description.abstract | The viscosity of biofluids can be used to acquire meaningful medical information on the conditions of a patient but has seldom been utilized in clinical practices owing to cumbersome measurement procedures and the need for large sample volumes. We present a colorimetric method to measure the viscosity of blood plasma using a paper-based viscometer developed in this study specifically for clinical diagnosis. The proposed analytical device consists of multilayered papers with fluid-loading -mixing, and-measuring regions, and it can be fabricated readily in a simple manner using three-layered paper channels and tape. Moreover, the colorimetric analysis enables viscosity estimations by analyzing a single optical image. To validate the device performance, we measured the viscosities of fluids such as glycerin aqueous solutions, bovine-serum-albumin solution, dimethyl sulfoxide, and blood plasma. We found that the measured viscosities were in good agreement with the reference values. Finally, we developed a simple smartphone application for the viscosity measurements that helped enhance the convenience and utility of the paper-based viscometer while maintaining the measurement accuracy. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | Development of a Paper-Based Viscometer for Blood Plasma Using Colorimetric Analysis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Song, Simon | - |
dc.contributor.affiliatedAuthor | Bae, Sang-Cheol | - |
dc.identifier.doi | 10.1021/acs.analchem.9b00624 | - |
dc.identifier.scopusid | 2-s2.0-85063365666 | - |
dc.identifier.wosid | 000463683300080 | - |
dc.identifier.bibliographicCitation | ANALYTICAL CHEMISTRY, v.91, no.7, pp.4868 - 4875 | - |
dc.relation.isPartOf | ANALYTICAL CHEMISTRY | - |
dc.citation.title | ANALYTICAL CHEMISTRY | - |
dc.citation.volume | 91 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 4868 | - |
dc.citation.endPage | 4875 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.subject.keywordPlus | MICROFLUIDIC VISCOMETER | - |
dc.subject.keywordPlus | ANALYTICAL DEVICE | - |
dc.subject.keywordPlus | SURFACE-TENSION | - |
dc.subject.keywordPlus | VISCOSITY | - |
dc.subject.keywordPlus | FLOW | - |
dc.subject.keywordPlus | POINT | - |
dc.subject.keywordPlus | CONSTITUENTS | - |
dc.subject.keywordPlus | DYNAMICS | - |
dc.subject.keywordPlus | CHANNEL | - |
dc.subject.keywordPlus | SERUM | - |
dc.identifier.url | https://pubs.acs.org/doi/10.1021/acs.analchem.9b00624 | - |
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