인후두 역류질환에서 양성자 펌프 억제제 치료가 삶의 질에 미치는 영향
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 최해원 | - |
dc.contributor.author | 전현웅 | - |
dc.contributor.author | 정진혁 | - |
dc.contributor.author | 김무건 | - |
dc.contributor.author | 태경 | - |
dc.contributor.author | 지용배 | - |
dc.date.accessioned | 2022-07-07T11:11:55Z | - |
dc.date.available | 2022-07-07T11:11:55Z | - |
dc.date.created | 2021-05-13 | - |
dc.date.issued | 2020-11 | - |
dc.identifier.issn | 2092-5859 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/144368 | - |
dc.description.abstract | Background and Objectives Several studies have assessed the impact of laryngopharyngeal reflux disease (LPRD) on the health-related quality of life (HR-QoL), showing significant impairment of HR-QoL. This study aims to assess the impact of proton pump inhibitor (PPI) treatment of LPRDs to enhance HR-QoL. Subjects and Method We prospectively collected data from LPRD patients from April 2017 to July 2019. Patients who have reflux symptom index (RSI) of ≥13 or reflux finding score (RFS) of ≥7 were enrolled in this study. We assessed HR-QoL using a questionnaire with EORTC QLQ-H&N35, -C30 on the first visit. Patients were treated with PPI (Ilaprazole 20 mg/day) on their visits at 4, 8, and 12 weeks. RSI and RFS were measured at each visit and HR-QoL was reevaluated on the last visit. Results Ninety-five patients completed the 3-months follow-up and were enrolled in this study. Female : male ratio was 71:24 and the mean age was 57.0±11.9 (27-80). The initial RSI and RFS were 16.3±8.8 and 12.6±2.9, respectively, but were changed to 11.1±9.7 and 9.7±2.6 (p<0.001 in both) at 12 weeks after the treatment. Global health status/QoL, speech problem, dry mouth, and coughing were significantly improved. Conclusion PPI administration is effective in treating LPRD, where effects begin to appear at 4 weeks after treatment. HR-QoL was also improved in patients who have RSI improvement. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | Korean Society of Otolaryngology | - |
dc.title | 인후두 역류질환에서 양성자 펌프 억제제 치료가 삶의 질에 미치는 영향 | - |
dc.title.alternative | Impact on Quality of Life after Treatment with Proton Pump Inhibitor in Laryngopharyngeal Reflux | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | 지용배 | - |
dc.identifier.doi | 10.3342/kjorl-hns.2019.00899 | - |
dc.identifier.scopusid | 2-s2.0-85098156601 | - |
dc.identifier.bibliographicCitation | Korean Journal of Otorhinolaryngology Head and Neck Surgery, v.63, no.11, pp.517 - 522 | - |
dc.relation.isPartOf | Korean Journal of Otorhinolaryngology Head and Neck Surgery | - |
dc.citation.title | Korean Journal of Otorhinolaryngology Head and Neck Surgery | - |
dc.citation.volume | 63 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 517 | - |
dc.citation.endPage | 522 | - |
dc.type.rims | ART | - |
dc.identifier.kciid | ART002651956 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | Laryngopharyngeal reflux | - |
dc.subject.keywordAuthor | Laryngoscopy | - |
dc.subject.keywordAuthor | Proton pump inhibitor | - |
dc.subject.keywordAuthor | Quality of life . | - |
dc.identifier.url | https://www.kjorl.org/journal/view.php?doi=10.3342/kjorl-hns.2019.00899 | - |
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