Synbiotic Effect of Whole Grape Seed Flour and Newly Isolated Kefir Lactic Acid Bacteria on Intestinal Microbiota of Diet-Induced Obese Mice
DC Field | Value | Language |
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dc.contributor.author | Seo, Kun-Ho | - |
dc.contributor.author | Kim, Dong-Hyeon | - |
dc.contributor.author | Yokoyama, Wallace H. | - |
dc.contributor.author | Kim, Hyunsook | - |
dc.date.accessioned | 2022-07-07T11:16:11Z | - |
dc.date.available | 2022-07-07T11:16:11Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2020-11 | - |
dc.identifier.issn | 0021-8561 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/144437 | - |
dc.description.abstract | Alterations of intestinal microbiota by synbiotic action of pre- and probiotics may confer health benefits to the host. In this study, high-throughput sequencing of 16S rRNA was used to analyze intestinal microbiota in feces, and the relative abundance of intestinal bacteria was correlated with physiological data from a prior study of a synbiotic combination of flavonoid-rich wine grape seed flour (WGF) and two newly isolated kefir lactic acid bacteria (LAB) in diet-induced obese mice. The combination of WGF and LAB enhanced observed operational taxonomic units and Chaol index compared to WGF alone, indicating an increase in the microbial community richness. The combination significantly enhanced abundance of Akkermansia muciniphila and Nocardia coeliaca and their abundance had an inverse relationship with body weight gain and adipose weight. In conclusion, the synbiotic effects of WGF and LAB on improvement of high-fat-diet-induced obesity are strongly linked to remodeling intestinal microbiota. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | Synbiotic Effect of Whole Grape Seed Flour and Newly Isolated Kefir Lactic Acid Bacteria on Intestinal Microbiota of Diet-Induced Obese Mice | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Hyunsook | - |
dc.identifier.doi | 10.1021/acs.jafc.0c01240 | - |
dc.identifier.scopusid | 2-s2.0-85081701264 | - |
dc.identifier.wosid | 000592922700038 | - |
dc.identifier.bibliographicCitation | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, v.68, no.46, pp.13131 - 13137 | - |
dc.relation.isPartOf | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | - |
dc.citation.title | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | - |
dc.citation.volume | 68 | - |
dc.citation.number | 46 | - |
dc.citation.startPage | 13131 | - |
dc.citation.endPage | 13137 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Agriculture | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Agriculture, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.subject.keywordPlus | Bacteria | - |
dc.subject.keywordPlus | Mammals | - |
dc.subject.keywordPlus | Nutrition | - |
dc.subject.keywordPlus | Probiotics | - |
dc.subject.keywordPlus | RNA | - |
dc.subject.keywordPlus | kefir | - |
dc.subject.keywordPlus | synbiotic agent | - |
dc.subject.keywordPlus | Lactic acid | - |
dc.subject.keywordPlus | anti-obesity | - |
dc.subject.keywordPlus | Grape seeds | - |
dc.subject.keywordPlus | High-throughput sequencing | - |
dc.subject.keywordPlus | Inverse relationship | - |
dc.subject.keywordPlus | Lactic acid bacteria | - |
dc.subject.keywordPlus | Microbial communities | - |
dc.subject.keywordPlus | Microbiotas | - |
dc.subject.keywordPlus | Operational taxonomic units | - |
dc.subject.keywordPlus | body weight | - |
dc.subject.keywordPlus | chemistry | - |
dc.subject.keywordPlus | classification | - |
dc.subject.keywordPlus | drug effect | - |
dc.subject.keywordPlus | feces | - |
dc.subject.keywordPlus | flour | - |
dc.subject.keywordPlus | genetics | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | intestine flora | - |
dc.subject.keywordPlus | isolation and purification | - |
dc.subject.keywordPlus | Lactobacillales | - |
dc.subject.keywordPlus | microbiology | - |
dc.subject.keywordPlus | obesity | - |
dc.subject.keywordPlus | pathophysiology | - |
dc.subject.keywordPlus | physiology | - |
dc.subject.keywordPlus | Vitis | - |
dc.subject.keywordAuthor | microbiota | - |
dc.subject.keywordAuthor | anti-obesity | - |
dc.subject.keywordAuthor | whole grape seed flour | - |
dc.subject.keywordAuthor | kefir lactic acid bacteria | - |
dc.identifier.url | https://pubs.acs.org/doi/10.1021/acs.jafc.0c01240 | - |
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