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Cited 15 time in webofscience Cited 15 time in scopus
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CD24 regulates stemness and the epithelial to mesenchymal transition through modulation of Notch1 mRNA stability by p38MAPK

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dc.contributor.authorLim, Juyeon-
dc.contributor.authorLee, Kyung-min-
dc.contributor.authorShim, Jaekyung-
dc.contributor.authorShin, Incheol-
dc.date.accessioned2022-07-07T13:30:32Z-
dc.date.available2022-07-07T13:30:32Z-
dc.date.created2021-05-12-
dc.date.issued2014-09-
dc.identifier.issn0003-9861-
dc.identifier.urihttps://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/144539-
dc.description.abstractWe report here that CD24 knockdown resulted in decreased expression of Notch1 in MCF-7 cells. CD24-downstream p38MAPK was shown to regulate Notch1 at the level of mRNA stability. We also found that CD24-mediated cell migration, invasion, mammosphere formation, and drug resistance was regulated by its downstream target Notch1. Together, our results indicate that CD24 may regulate the epithelial to mesenchymal transition and sternness through Notch1 signaling in breast cancer cells.-
dc.language영어-
dc.language.isoen-
dc.publisherELSEVIER SCIENCE INC-
dc.titleCD24 regulates stemness and the epithelial to mesenchymal transition through modulation of Notch1 mRNA stability by p38MAPK-
dc.typeArticle-
dc.contributor.affiliatedAuthorShin, Incheol-
dc.identifier.doi10.1016/j.abb.2014.06.022-
dc.identifier.scopusid2-s2.0-84905022679-
dc.identifier.wosid000340701600015-
dc.identifier.bibliographicCitationARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, v.558, pp.120 - 126-
dc.relation.isPartOfARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS-
dc.citation.titleARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS-
dc.citation.volume558-
dc.citation.startPage120-
dc.citation.endPage126-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalResearchAreaBiophysics-
dc.relation.journalWebOfScienceCategoryBiochemistry & Molecular Biology-
dc.relation.journalWebOfScienceCategoryBiophysics-
dc.subject.keywordPlusBREAST-CARCINOMA CELLS-
dc.subject.keywordPlusP-SELECTIN-
dc.subject.keywordPlusPROGNOSTIC MARKER-
dc.subject.keywordPlusOVARIAN-CANCER-
dc.subject.keywordPlusLIGAND-
dc.subject.keywordPlusCYCLOOXYGENASE-2-
dc.subject.keywordPlusPROLIFERATION-
dc.subject.keywordPlusTRANSCRIPTION-
dc.subject.keywordPlusACTIVATION-
dc.subject.keywordPlusEXPRESSION-
dc.subject.keywordAuthorBreast cancer-
dc.subject.keywordAuthorCD24-
dc.subject.keywordAuthorCSC-
dc.subject.keywordAuthorEMT-
dc.subject.keywordAuthorNotch1-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0003986114002240?via%3Dihub-
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