Microfluidic Image Cytometry (mu FIC) Assessments of Silver Nanoparticle Cytotoxicity
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Jonghoon | - |
dc.contributor.author | Yoon, Tae Hyun | - |
dc.date.accessioned | 2022-07-07T13:38:20Z | - |
dc.date.available | 2022-07-07T13:38:20Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2012-12 | - |
dc.identifier.issn | 0253-2964 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/144690 | - |
dc.description.abstract | Cytotoxicity assessment of silver nanoparticles (AgNPs) was performed using MTT-based microfluidic image cytometry (mu FIC). The LC50 value of HeLa cells exposed to AgNPs in the microfluidic device was estimated as 46.7 mg/L, which is similar to that estimated by MTT-based IC for cells cultured in a 96 well plate (49.9 mg/L). These results confirm that the mu FIC approach can produce cytotoxicity data that is reasonably well-matched with that of the conventional 96 well plate system with much higher efficiency. This mu FIC method provides many benefits including ease of use and low cost, and is a more rapid in vitro cell based assay for AgNPs. This may aid in speeding up data acquisition in the field of nanosafety and make a significant contribution to the quantitative understanding of nanoproperty- toxicity relationships. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.title | Microfluidic Image Cytometry (mu FIC) Assessments of Silver Nanoparticle Cytotoxicity | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yoon, Tae Hyun | - |
dc.identifier.doi | 10.5012/bkcs.2012.33.12.4023 | - |
dc.identifier.scopusid | 2-s2.0-84871751994 | - |
dc.identifier.wosid | 000313154400020 | - |
dc.identifier.bibliographicCitation | BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.33, no.12, pp.4023 - 4027 | - |
dc.relation.isPartOf | BULLETIN OF THE KOREAN CHEMICAL SOCIETY | - |
dc.citation.title | BULLETIN OF THE KOREAN CHEMICAL SOCIETY | - |
dc.citation.volume | 33 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 4023 | - |
dc.citation.endPage | 4027 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001718733 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.subject.keywordPlus | DEVICE | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordAuthor | Microfluidic image cytometry | - |
dc.subject.keywordAuthor | Microfluidic device | - |
dc.subject.keywordAuthor | Cytotoxicity assessment | - |
dc.subject.keywordAuthor | Ag nanoparticles | - |
dc.subject.keywordAuthor | Nanotoxicity | - |
dc.identifier.url | http://koreascience.or.kr/article/JAKO201202950483926.page | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.