Polarization-extinction-based detection of DNA hybridization in situ using a nanoparticle wire-grid polarizer
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yu, Hojeong | - |
dc.contributor.author | Oh, Youngjin | - |
dc.contributor.author | Kim, Soowon | - |
dc.contributor.author | Song, Seok Ho | - |
dc.contributor.author | Kim, Donghyun | - |
dc.date.accessioned | 2022-07-07T13:46:18Z | - |
dc.date.available | 2022-07-07T13:46:18Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2012-09 | - |
dc.identifier.issn | 0146-9592 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/144719 | - |
dc.description.abstract | Metallic wires can discriminate light polarization due to strong absorption of electric fields oscillating in parallel to wires. Here, we explore polarization-based biosensing of DNA hybridization in situ by employing metal target-conjugated nanoparticles to form a wire-grid polarizer (WGP) as complementary DNA strands hybridize. Experimental results using gold nanoparticles of 15 nm diameter to form a WGP of 400 nm period suggest that polarization extinction can detect DNA hybridization with a limit of detection in the range of 1 nM concentration. The sensitivity may be improved by more than an order of magnitude if larger nanoparticles are employed to define WGPs at a period between 400 and 500 nm. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | OPTICAL SOC AMER | - |
dc.title | Polarization-extinction-based detection of DNA hybridization in situ using a nanoparticle wire-grid polarizer | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Song, Seok Ho | - |
dc.identifier.doi | 10.1364/OL.37.003867 | - |
dc.identifier.scopusid | 2-s2.0-84866286083 | - |
dc.identifier.wosid | 000309046300043 | - |
dc.identifier.bibliographicCitation | OPTICS LETTERS, v.37, no.18, pp.3867 - 3869 | - |
dc.relation.isPartOf | OPTICS LETTERS | - |
dc.citation.title | OPTICS LETTERS | - |
dc.citation.volume | 37 | - |
dc.citation.number | 18 | - |
dc.citation.startPage | 3867 | - |
dc.citation.endPage | 3869 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Optics | - |
dc.relation.journalWebOfScienceCategory | Optics | - |
dc.subject.keywordPlus | PLASMON RESONANCE DETECTION | - |
dc.subject.keywordPlus | FABRICATION | - |
dc.subject.keywordPlus | GRATINGS | - |
dc.subject.keywordPlus | SENSOR | - |
dc.subject.keywordPlus | GLASS | - |
dc.identifier.url | https://opg.optica.org/ol/fulltext.cfm?uri=ol-37-18-3867&id=241411 | - |
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