Pan-cancer analysis of whole genomes
DC Field | Value | Language |
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dc.contributor.author | Campbell, Peter J. | - |
dc.contributor.author | Getz, Gad | - |
dc.contributor.author | Korbel, Jan O. | - |
dc.contributor.author | Stuart, Joshua M. | - |
dc.contributor.author | Jennings, Jennifer L. | - |
dc.contributor.author | Stein, Lincoln D. | - |
dc.contributor.author | Perry, Marc D. | - |
dc.contributor.author | Ouellette, B. F. Francis | - |
dc.contributor.author | Nahal-Bose, Hardeep K. | - |
dc.contributor.author | Li, Constance H. | - |
dc.contributor.author | Rheinbay, Esther | - |
dc.contributor.author | Nielsen, G. Petur | - |
dc.contributor.author | Sgroi, Dennis C. | - |
dc.contributor.author | Wu, Chin-Lee | - |
dc.contributor.author | Faquin, William C. | - |
dc.contributor.author | Deshpande, Vikram | - |
dc.contributor.author | Boutros, Paul C. | - |
dc.contributor.author | Lazar, Alexander J. | - |
dc.contributor.author | Hoadley, Katherine A. | - |
dc.contributor.author | Louis, David N. | - |
dc.contributor.author | Dursi, L. Jonathan | - |
dc.contributor.author | Yung, Christina K. | - |
dc.contributor.author | Bailey, Matthew H. | - |
dc.contributor.author | Saksena, Gordon | - |
dc.contributor.author | Raine, Keiran M. | - |
dc.contributor.author | Buchhalter, Ivo | - |
dc.contributor.author | Kleinheinz, Kortine | - |
dc.contributor.author | Schlesner, Matthias | - |
dc.contributor.author | Zhang, Junjun | - |
dc.contributor.author | Wang, Wenyi | - |
dc.contributor.author | Wheeler, David A. | - |
dc.contributor.author | Ding, Li | - |
dc.contributor.author | Simpson, Jared T. | - |
dc.contributor.author | O'Connor, Brian D. | - |
dc.contributor.author | Yakneen, Sergei | - |
dc.contributor.author | Ellrott, Kyle | - |
dc.contributor.author | Miyoshi, Naoki | - |
dc.contributor.author | Butler, Adam P. | - |
dc.contributor.author | Royo, Romina | - |
dc.contributor.author | Shorser, Solomon, I | - |
dc.contributor.author | Vazquez, Miguel | - |
dc.contributor.author | Rausch, Tobias | - |
dc.contributor.author | Tiao, Grace | - |
dc.contributor.author | Waszak, Sebastian M. | - |
dc.contributor.author | Rodriguez-Martin, Bernardo | - |
dc.contributor.author | Shringarpure, Suyash | - |
dc.contributor.author | Wu, Dai-Ying | - |
dc.contributor.author | Demidov, German M. | - |
dc.contributor.author | Delaneau, Olivier | - |
dc.contributor.author | Hayashi, Shuto | - |
dc.contributor.author | Imoto, Seiya | - |
dc.contributor.author | Habermann, Nina | - |
dc.contributor.author | Segre, Ayellet, V | - |
dc.contributor.author | Garrison, Erik | - |
dc.contributor.author | Cafferkey, Andy | - |
dc.contributor.author | Alvarez, Eva G. | - |
dc.contributor.author | Maria Heredia-Genestar, Jose | - |
dc.contributor.author | Muyas, Francesc | - |
dc.contributor.author | Drechsel, Oliver | - |
dc.contributor.author | Bruzos, Alicia L. | - |
dc.contributor.author | Temes, Javier | - |
dc.contributor.author | Zamora, Jorge | - |
dc.contributor.author | Baez-Ortega, Adrian | - |
dc.contributor.author | Kim, Hyung-Lae | - |
dc.contributor.author | Mashl, R. Jay | - |
dc.contributor.author | Ye, Kai | - |
dc.contributor.author | DiBiase, Anthony | - |
dc.contributor.author | Huang, Kuan-lin | - |
dc.contributor.author | Letunic, Ivica | - |
dc.contributor.author | McLellan, Michael D. | - |
dc.contributor.author | Newhouse, Steven J. | - |
dc.contributor.author | Shmaya, Tal | - |
dc.contributor.author | Kumar, Sushant | - |
dc.contributor.author | Wedge, David C. | - |
dc.contributor.author | Wright, Mark H. | - |
dc.contributor.author | Yellapantula, Venkata D. | - |
dc.contributor.author | Gerstein, Mark | - |
dc.contributor.author | Khurana, Ekta | - |
dc.contributor.author | Marques-Bonet, Tomas | - |
dc.contributor.author | Navarro, Arcadi | - |
dc.contributor.author | Bustamante, Carlos D. | - |
dc.contributor.author | Siebert, Reiner | - |
dc.contributor.author | Nakagawa, Hidewaki | - |
dc.contributor.author | Easton, Douglas F. | - |
dc.contributor.author | Ossowski, Stephan | - |
dc.contributor.author | Tubio, Jose M. C. | - |
dc.contributor.author | De La Vega, Francisco M. | - |
dc.contributor.author | Estivill, Xavier | - |
dc.contributor.author | Yuen, Denis | - |
dc.contributor.author | Mihaiescu, George L. | - |
dc.contributor.author | Omberg, Larsson | - |
dc.contributor.author | Ferretti, Vincent | - |
dc.contributor.author | Sabarinathan, Radhakrishnan | - |
dc.contributor.author | Pich, Oriol | - |
dc.contributor.author | Gonzalez-Perez, Abel | - |
dc.contributor.author | Weiner, Amaro Taylor | - |
dc.contributor.author | Fittall, Matthew W. | - |
dc.contributor.author | Demeulemeester, Jonas | - |
dc.contributor.author | Tarabichi, Maxime | - |
dc.contributor.author | Roberts, Nicola D. | - |
dc.contributor.author | Van Loo, Peter | - |
dc.contributor.author | Cortes-Ciriano, Isidro | - |
dc.contributor.author | Urban, Lara | - |
dc.contributor.author | Park, Peter | - |
dc.contributor.author | Bin Zhu | - |
dc.contributor.author | Pitkaenen, Esa | - |
dc.contributor.author | Li, Yilong | - |
dc.contributor.author | Saini, Natalie | - |
dc.contributor.author | Klimczak, Leszek J. | - |
dc.contributor.author | Weischenfeldt, Joachim | - |
dc.contributor.author | Sidiropoulos, Nikos | - |
dc.contributor.author | Alexandrov, Ludmil B. | - |
dc.contributor.author | Rabionet, Raquel | - |
dc.contributor.author | Escaramis, Georgia | - |
dc.contributor.author | Bosio, Mattia | - |
dc.contributor.author | Holik, Aliaksei Z. | - |
dc.contributor.author | Susak, Hana | - |
dc.contributor.author | Prasad, Aparna | - |
dc.contributor.author | Erkek, Serap | - |
dc.contributor.author | Calabrese, Claudia | - |
dc.contributor.author | Raeder, Benjamin | - |
dc.contributor.author | Harrington, Eoghan | - |
dc.contributor.author | Mayes, Simon | - |
dc.contributor.author | Turner, Daniel | - |
dc.contributor.author | Juul, Sissel | - |
dc.contributor.author | Roberts, Steven A. | - |
dc.contributor.author | Song, Lei | - |
dc.contributor.author | Koster, Roelof | - |
dc.contributor.author | Mirabello, Lisa | - |
dc.contributor.author | Hua, Xing | - |
dc.contributor.author | Tanskanen, Tomas J. | - |
dc.contributor.author | Tojo, Marta | - |
dc.contributor.author | Chen, Jieming | - |
dc.contributor.author | Aaltonen, Lauri A. | - |
dc.contributor.author | Ratsch, Gunnar | - |
dc.contributor.author | Schwarz, Roland F. | - |
dc.contributor.author | Butte, Atul J. | - |
dc.contributor.author | Brazma, Alvis | - |
dc.contributor.author | Chanock, Stephen J. | - |
dc.contributor.author | Chatterjee, Nilanjan | - |
dc.contributor.author | Stegle, Oliver | - |
dc.contributor.author | Harismendy, Olivier | - |
dc.contributor.author | Bova, G. Steven | - |
dc.contributor.author | Gordenin, Dmitry A. | - |
dc.contributor.author | Haan, David | - |
dc.contributor.author | Sieverling, Lina | - |
dc.contributor.author | Feuerbach, Lars | - |
dc.contributor.author | Chalmers, Don | - |
dc.contributor.author | Joly, Yann | - |
dc.contributor.author | Knoppers, Bartha | - |
dc.contributor.author | Molnar-Gabor, Fruzsina | - |
dc.contributor.author | Phillips, Mark | - |
dc.contributor.author | Thorogood, Adrian | - |
dc.contributor.author | Townend, David | - |
dc.contributor.author | Goldman, Mary | - |
dc.contributor.author | Fonseca, Nuno A. | - |
dc.contributor.author | Xiang, Qian | - |
dc.contributor.author | Craft, Brian | - |
dc.contributor.author | Pineiro-Yanez, Elena | - |
dc.contributor.author | Munoz, Alfonso | - |
dc.contributor.author | Petryszak, Robert | - |
dc.contributor.author | Fullgrabe, Anja | - |
dc.contributor.author | Al-Shahrour, Fatima | - |
dc.contributor.author | Keays, Maria | - |
dc.contributor.author | Haussler, David | - |
dc.contributor.author | Weinstein, John | - |
dc.contributor.author | Huber, Wolfgang | - |
dc.contributor.author | Valencia, Alfonso | - |
dc.contributor.author | Papatheodorou, Irene | - |
dc.contributor.author | Zhu, Jingchun | - |
dc.contributor.author | Fan, Yu | - |
dc.contributor.author | Torrents, David | - |
dc.contributor.author | Bieg, Matthias | - |
dc.contributor.author | Chen, Ken | - |
dc.contributor.author | Chong, Zechen | - |
dc.contributor.author | Cibulskis, Kristian | - |
dc.contributor.author | Eils, Roland | - |
dc.contributor.author | Fulton, Robert S. | - |
dc.contributor.author | Gelpi, Josep L. | - |
dc.contributor.author | Gonzalez, Santiago | - |
dc.contributor.author | Gut, Ivo G. | - |
dc.contributor.author | Hach, Faraz | - |
dc.contributor.author | Heinold, Michael | - |
dc.contributor.author | Hu, Taobo | - |
dc.contributor.author | Huang, Vincent | - |
dc.contributor.author | Hutter, Barbara | - |
dc.contributor.author | Jaeger, Natalie | - |
dc.contributor.author | Jung, Jongsun | - |
dc.contributor.author | Kumar, Yogesh | - |
dc.contributor.author | Lalansingh, Christopher | - |
dc.contributor.author | Leshchiner, Ignaty | - |
dc.contributor.author | Livitz, Dimitri | - |
dc.contributor.author | Ma, Eric Z. | - |
dc.contributor.author | Maruvka, Yosef E. | - |
dc.contributor.author | Milovanovic, Ana | - |
dc.contributor.author | Nielsen, Morten Muhlig | - |
dc.contributor.author | Paramasivam, Nagarajan | - |
dc.contributor.author | Pedersen, Jakob Skou | - |
dc.contributor.author | Puiggros, Montserrat | - |
dc.contributor.author | Sahinalp, S. Cenk | - |
dc.contributor.author | Sarrafi, Iman | - |
dc.contributor.author | Stewart, Chip | - |
dc.contributor.author | Stobbe, Miranda D. | - |
dc.contributor.author | Wala, Jeremiah A. | - |
dc.contributor.author | Wang, Jiayin | - |
dc.contributor.author | Wendl, Michael | - |
dc.contributor.author | Werner, Johannes | - |
dc.contributor.author | Wu, Zhenggang | - |
dc.contributor.author | Xue, Hong | - |
dc.contributor.author | Yamaguchi, Takafumi N. | - |
dc.contributor.author | Yellapantula, Venkata | - |
dc.contributor.author | Davis-Dusenbery, Brandi N. | - |
dc.contributor.author | Grossman, Robert L. | - |
dc.contributor.author | Kim, Youngwook | - |
dc.contributor.author | Heinold, Michael C. | - |
dc.contributor.author | Hinton, Jonathan | - |
dc.contributor.author | Jones, David R. | - |
dc.contributor.author | Menzies, Andrew | - |
dc.contributor.author | Stebbings, Lucy | - |
dc.contributor.author | Hess, Julian M. | - |
dc.contributor.author | Rosenberg, Mara | - |
dc.contributor.author | Dunford, Andrew J. | - |
dc.contributor.author | Gupta, Manaswi | - |
dc.contributor.author | Imielinski, Marcin | - |
dc.contributor.author | Meyerson, Matthew | - |
dc.contributor.author | Beroukhim, Rameen | - |
dc.contributor.author | Reimand, Juri | - |
dc.contributor.author | Dhingra, Priyanka | - |
dc.contributor.author | Favero, Francesco | - |
dc.contributor.author | Dentro, Stefan | - |
dc.contributor.author | Wintersinger, Jeff | - |
dc.contributor.author | Rudneva, Vasilisa | - |
dc.contributor.author | Park, Ji Wan | - |
dc.contributor.author | Hong, Eun Pyo | - |
dc.contributor.author | Heo, Seong Gu | - |
dc.contributor.author | Kahles, Andre | - |
dc.contributor.author | Kjong-Van Lehmann | - |
dc.contributor.author | Soulette, Cameron M. | - |
dc.contributor.author | Shiraishi, Yuichi | - |
dc.contributor.author | Liu, Fenglin | - |
dc.contributor.author | He, Yao | - |
dc.contributor.author | Demircioglu, Deniz | - |
dc.contributor.author | Davidson, Natalie R. | - |
dc.contributor.author | Greger, Liliana | - |
dc.contributor.author | Li, Siliang | - |
dc.contributor.author | Liu, Dongbing | - |
dc.contributor.author | Stark, Stefan G. | - |
dc.contributor.author | Zhang, Fan | - |
dc.contributor.author | Amin, Samirkumar B. | - |
dc.contributor.author | Bailey, Peter | - |
dc.contributor.author | Chateigner, Aurelien | - |
dc.contributor.author | Frenkel-Morgenstern, Milana | - |
dc.contributor.author | Hou, Yong | - |
dc.contributor.author | Huska, Matthew R. | - |
dc.contributor.author | Kilpinen, Helena | - |
dc.contributor.author | Lamaze, Fabien C. | - |
dc.contributor.author | Li, Chang | - |
dc.contributor.author | Li, Xiaobo | - |
dc.contributor.author | Li, Xinyue | - |
dc.contributor.author | Liu, Xingmin | - |
dc.contributor.author | Marin, Maximillian G. | - |
dc.contributor.author | Markowski, Julia | - |
dc.contributor.author | Nandi, Tannistha | - |
dc.contributor.author | Ojesina, Akinyemi, I | - |
dc.contributor.author | Pan-Hammarstrom, Qiang | - |
dc.contributor.author | Park, Peter J. | - |
dc.contributor.author | Pedamallu, Chandra Sekhar | - |
dc.contributor.author | Su, Hong | - |
dc.contributor.author | Tan, Patrick | - |
dc.contributor.author | Teh, Bin Tean | - |
dc.contributor.author | Wang, Jian | - |
dc.contributor.author | Xiong, Heng | - |
dc.contributor.author | Ye, Chen | - |
dc.contributor.author | Yung, Christina | - |
dc.contributor.author | Zhang, Xiuqing | - |
dc.contributor.author | Zheng, Liangtao | - |
dc.contributor.author | Zhu, Shida | - |
dc.contributor.author | Awadalla, Philip | - |
dc.contributor.author | Creighton, Chad J. | - |
dc.contributor.author | Wu, Kui | - |
dc.contributor.author | Yang, Huanming | - |
dc.contributor.author | Goke, Jonathan | - |
dc.contributor.author | Zhang, Zemin | - |
dc.contributor.author | Brooks, Angela N. | - |
dc.contributor.author | Martincorena, Inigo | - |
dc.contributor.author | Rubio-Perez, Carlota | - |
dc.contributor.author | Juul, Malene | - |
dc.contributor.author | Schumacher, Steven | - |
dc.contributor.author | Shapira, Ofer | - |
dc.contributor.author | Tamborero, David | - |
dc.contributor.author | Mularoni, Loris | - |
dc.contributor.author | Hornshoj, Henrik | - |
dc.contributor.author | Deu-Pons, Jordi | - |
dc.contributor.author | Muinos, Ferran | - |
dc.contributor.author | Bertl, Johanna | - |
dc.contributor.author | Guo, Qianyun | - |
dc.contributor.author | Bazant, Wojciech | - |
dc.contributor.author | Barrera, Elisabet | - |
dc.contributor.author | Al-Sedairy, Sultan T. | - |
dc.contributor.author | Aretz, Axel | - |
dc.contributor.author | Bell, Cindy | - |
dc.contributor.author | Betancourt, Miguel | - |
dc.contributor.author | Buchholz, Christiane | - |
dc.contributor.author | Calvo, Fabien | - |
dc.contributor.author | Chomienne, Christine | - |
dc.contributor.author | Dunn, Michael | - |
dc.contributor.author | Edmonds, Stuart | - |
dc.contributor.author | Green, Eric | - |
dc.contributor.author | Gupta, Shailja | - |
dc.contributor.author | Hutter, Carolyn M. | - |
dc.contributor.author | Jegalian, Karine | - |
dc.contributor.author | Jones, Nic | - |
dc.contributor.author | Lu, Youyong | - |
dc.contributor.author | Nakagama, Hitoshi | - |
dc.contributor.author | Nettekoven, Gerd | - |
dc.contributor.author | Planko, Laura | - |
dc.contributor.author | Scott, David | - |
dc.contributor.author | Shibata, Tatsuhiro | - |
dc.contributor.author | Shimizu, Kiyo | - |
dc.contributor.author | Stratton, Michael R. | - |
dc.contributor.author | Yugawa, Takashi | - |
dc.contributor.author | Tortora, Giampaolo | - |
dc.contributor.author | VijayRaghavan, K. | - |
dc.contributor.author | Zenklusen, Jean C. | - |
dc.contributor.author | Knoppers, Bartha M. | - |
dc.contributor.author | Aminou, Brice | - |
dc.contributor.author | Bartolome, Javier | - |
dc.contributor.author | Boroevich, Keith A. | - |
dc.contributor.author | Boyce, Rich | - |
dc.contributor.author | Buchanan, Alex | - |
dc.contributor.author | Byrne, Niall J. | - |
dc.contributor.author | Chen, Zhaohong | - |
dc.contributor.author | Cho, Sunghoon | - |
dc.contributor.author | Choi, Wan | - |
dc.contributor.author | Clapham, Peter | - |
dc.contributor.author | Dow, Michelle T. | - |
dc.contributor.author | Dursi, Lewis Jonathan | - |
dc.contributor.author | Eils, Juergen | - |
dc.contributor.author | Farcas, Claudiu | - |
dc.contributor.author | Fayzullaev, Nodirjon | - |
dc.contributor.author | Flicek, Paul | - |
dc.contributor.author | Heath, Allison P. | - |
dc.contributor.author | Hofmann, Oliver | - |
dc.contributor.author | Hong, Jongwhi H. | - |
dc.contributor.author | Hudson, Thomas J. | - |
dc.contributor.author | Huebschmann, Daniel | - |
dc.contributor.author | Ivkovic, Sinisa | - |
dc.contributor.author | Jeon, Seung-Hyup | - |
dc.contributor.author | Jiao, Wei | - |
dc.contributor.author | Kabbe, Rolf | - |
dc.contributor.author | Kerssemakers, Jules N. A. | - |
dc.contributor.author | Kim, Hyunghwan | - |
dc.contributor.author | Kim, Jihoon | - |
dc.contributor.author | Koscher, Michael | - |
dc.contributor.author | Koures, Antonios | - |
dc.contributor.author | Kovacevic, Milena | - |
dc.contributor.author | Lawerenz, Chris | - |
dc.contributor.author | Liu, Jia | - |
dc.contributor.author | Mijalkovic, Sanja | - |
dc.contributor.author | Mijalkovic-Lazic, Ana Mijalkovic | - |
dc.contributor.author | Miyano, Satoru | - |
dc.contributor.author | Nastic, Mia | - |
dc.contributor.author | Nicholson, Jonathan | - |
dc.contributor.author | Ocana, David | - |
dc.contributor.author | Ohi, Kazuhiro | - |
dc.contributor.author | Ohno-Machado, Lucila | - |
dc.contributor.author | Pihl, Todd D. | - |
dc.contributor.author | Prinz, Manuel | - |
dc.contributor.author | Radovic, Petar | - |
dc.contributor.author | Short, Charles | - |
dc.contributor.author | Sofia, Heidi J. | - |
dc.contributor.author | Spring, Jonathan | - |
dc.contributor.author | Struck, Adam J. | - |
dc.contributor.author | Tijanic, Nebojsa | - |
dc.contributor.author | Vicente, David | - |
dc.contributor.author | Wang, Zhining | - |
dc.contributor.author | Williams, Ashley | - |
dc.contributor.author | Woo, Youngchoon | - |
dc.contributor.author | Wright, Adam J. | - |
dc.contributor.author | Yang, Liming | - |
dc.contributor.author | Hamilton, Mark P. | - |
dc.contributor.author | Johnson, Todd A. | - |
dc.contributor.author | Kahraman, Abdullah | - |
dc.contributor.author | Kellis, Manolis | - |
dc.contributor.author | Polak, Paz | - |
dc.contributor.author | Sallari, Richard | - |
dc.contributor.author | Sinnott-Armstrong, Nasa | - |
dc.contributor.author | von Mering, Christian | - |
dc.contributor.author | Beltran, Sergi | - |
dc.contributor.author | Gerhard, Daniela S. | - |
dc.contributor.author | Gut, Marta | - |
dc.contributor.author | Trotta, Jean-Remi | - |
dc.contributor.author | Whalley, Justin P. | - |
dc.contributor.author | Niu, Beifang | - |
dc.contributor.author | Espiritu, Shadrielle M. G. | - |
dc.contributor.author | Gao, Shengjie | - |
dc.contributor.author | Huang, Yi | - |
dc.contributor.author | Lalansingh, Christopher M. | - |
dc.contributor.author | Teague, Jon W. | - |
dc.contributor.author | Wendl, Michael C. | - |
dc.contributor.author | Abascal, Federico | - |
dc.contributor.author | Bader, Gary D. | - |
dc.contributor.author | Bandopadhayay, Pratiti | - |
dc.contributor.author | Barenboim, Jonathan | - |
dc.contributor.author | Brunak, Soren | - |
dc.contributor.author | Fita, Joana Carlevaro | - |
dc.contributor.author | Chakravarty, Dimple | - |
dc.contributor.author | Chan, Calvin Wing Yiu | - |
dc.contributor.author | Choi, Jung Kyoon | - |
dc.contributor.author | Diamanti, Klev | - |
dc.contributor.author | Fink, J. Lynn | - |
dc.contributor.author | Frigola, Joan | - |
dc.contributor.author | Gambacorti-Passerini, Carlo | - |
dc.contributor.author | Garsed, Dale W. | - |
dc.contributor.author | Haradhvala, Nicholas J. | - |
dc.contributor.author | Harmanci, Arif O. | - |
dc.contributor.author | Helmy, Mohamed | - |
dc.contributor.author | Herrmann, Carl | - |
dc.contributor.author | Hobolth, Asger | - |
dc.contributor.author | Hodzic, Ermin | - |
dc.contributor.author | Hong, Chen | - |
dc.contributor.author | Isaev, Keren | - |
dc.contributor.author | Izarzugaza, Jose M. G. | - |
dc.contributor.author | Johnson, Rory | - |
dc.contributor.author | Juul, Randi Istrup | - |
dc.contributor.author | Kim, Jaegil | - |
dc.contributor.author | Kim, Jong K. | - |
dc.contributor.author | Komorowski, Jan | - |
dc.contributor.author | Lanzos, Andres | - |
dc.contributor.author | Larsson, Erik | - |
dc.contributor.author | Lee, Donghoon | - |
dc.contributor.author | Li, Shantao | - |
dc.contributor.author | Li, Xiaotong | - |
dc.contributor.author | Lin, Ziao | - |
dc.contributor.author | Liu, Eric Minwei | - |
dc.contributor.author | Lochovsky, Lucas | - |
dc.contributor.author | Lou, Shaoke | - |
dc.contributor.author | Madsen, Tobias | - |
dc.contributor.author | Marchal, Kathleen | - |
dc.contributor.author | Fundichely, Alexander Martinez | - |
dc.contributor.author | McGillivray, Patrick D. | - |
dc.contributor.author | Meyerson, William | - |
dc.contributor.author | Paczkowska, Marta | - |
dc.contributor.author | Park, Keunchil | - |
dc.contributor.author | Park, Kiejung | - |
dc.contributor.author | Pons, Tirso | - |
dc.contributor.author | Pulido-Tamayo, Sergio | - |
dc.contributor.author | Reyes Salazar, Iker | - |
dc.contributor.author | Reyna, Matthew A. | - |
dc.contributor.author | Rubin, Mark A. | - |
dc.contributor.author | Salichos, Leonidas | - |
dc.contributor.author | Sander, Chris | - |
dc.contributor.author | Schumacher, Steven E. | - |
dc.contributor.author | Shackleton, Mark | - |
dc.contributor.author | Shen, Ciyue | - |
dc.contributor.author | Shrestha, Raunak | - |
dc.contributor.author | Shuai, Shimin | - |
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dc.contributor.author | Tam, Angela | - |
dc.contributor.author | Tan, Donghui | - |
dc.contributor.author | Tarnuzzer, Roy | - |
dc.contributor.author | Thiessen, Nina | - |
dc.contributor.author | Thompson, R. Houston | - |
dc.contributor.author | Thorne, Leigh B. | - |
dc.contributor.author | Tsao, Ming | - |
dc.contributor.author | Umbricht, Christopher | - |
dc.contributor.author | Van Den Berg, David J. | - |
dc.contributor.author | Van Meir, Erwin G. | - |
dc.contributor.author | Veluvolu, Umadevi | - |
dc.contributor.author | Voet, Douglas | - |
dc.contributor.author | Wang, Linghua | - |
dc.contributor.author | Weinberger, Paul | - |
dc.contributor.author | Weisenberger, Daniel J. | - |
dc.contributor.author | Wigle, Dennis | - |
dc.contributor.author | Wilkerson, Matthew D. | - |
dc.contributor.author | Wilson, Richard K. | - |
dc.contributor.author | Winterhoff, Boris | - |
dc.contributor.author | Wiznerowicz, Maciej | - |
dc.contributor.author | Wong, Tina | - |
dc.contributor.author | Wong, Winghing | - |
dc.contributor.author | Xi, Liu | - |
dc.contributor.author | Yau, Christina | - |
dc.contributor.author | Zhang, Hailei | - |
dc.contributor.author | Zhang, Hongxin | - |
dc.contributor.author | Zhang, Jiashan | - |
dc.date.accessioned | 2022-07-08T14:47:55Z | - |
dc.date.available | 2022-07-08T14:47:55Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2020-02 | - |
dc.identifier.issn | 0028-0836 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/146243 | - |
dc.description.abstract | Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale(1-3). Here we report the integrative analysis of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA). We describe the generation of the PCAWG resource, facilitated by international data sharing using compute clouds. On average, cancer genomes contained 4-5 driver mutations when combining coding and non-coding genomic elements; however, in around 5% of cases no drivers were identified, suggesting that cancer driver discovery is not yet complete. Chromothripsis, in which many clustered structural variants arise in a single catastrophic event, is frequently an early event in tumour evolution; in acral melanoma, for example, these events precede most somatic point mutations and affect several cancer-associated genes simultaneously. Cancers with abnormal telomere maintenance often originate from tissues with low replicative activity and show several mechanisms of preventing telomere attrition to critical levels. Common and rare germline variants affect patterns of somatic mutation, including point mutations, structural variants and somatic retrotransposition. A collection of papers from the PCAWG Consortium describes non-coding mutations that drive cancer beyond those in the TERT promoter(4); identifies new signatures of mutational processes that cause base substitutions, small insertions and deletions and structural variation(5,6); analyses timings and patterns of tumour evolution(7); describes the diverse transcriptional consequences of somatic mutation on splicing, expression levels, fusion genes and promoter activity(8,9); and evaluates a range of more-specialized features of cancer genomes(8,10-18). | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | NATURE PORTFOLIO | - |
dc.title | Pan-cancer analysis of whole genomes | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kong, Gu | - |
dc.contributor.affiliatedAuthor | Lee, Jeong-Yeon | - |
dc.identifier.doi | 10.1038/s41586-020-1969-6 | - |
dc.identifier.scopusid | 2-s2.0-85079038817 | - |
dc.identifier.wosid | 000529097800007 | - |
dc.identifier.bibliographicCitation | NATURE, v.578, no.7793, pp.82 - 93 | - |
dc.relation.isPartOf | NATURE | - |
dc.citation.title | NATURE | - |
dc.citation.volume | 578 | - |
dc.citation.number | 7793 | - |
dc.citation.startPage | 82 | - |
dc.citation.endPage | 93 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | TERT PROMOTER MUTATIONS | - |
dc.subject.keywordPlus | SOMATIC MUTATIONS | - |
dc.subject.keywordPlus | COMPREHENSIVE CHARACTERIZATION | - |
dc.subject.keywordPlus | SYSTEMATIC ANALYSIS | - |
dc.subject.keywordPlus | DNA-DAMAGE | - |
dc.subject.keywordPlus | LANDSCAPE | - |
dc.subject.keywordPlus | SIGNATURES | - |
dc.subject.keywordPlus | REARRANGEMENTS | - |
dc.subject.keywordPlus | EVOLUTION | - |
dc.subject.keywordPlus | PATTERNS | - |
dc.identifier.url | https://www.nature.com/articles/s41586-020-1969-6 | - |
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