Short-term effects of multiple outdoor environmental factors on risk of asthma exacerbations: Age-stratified time-series analysis
DC Field | Value | Language |
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dc.contributor.author | Lee, Seung Won | - |
dc.contributor.author | Yon, Dong Keon | - |
dc.contributor.author | James, Chase C. | - |
dc.contributor.author | Lee, Shinhae | - |
dc.contributor.author | Koh, Hyun Yong | - |
dc.contributor.author | Sheen, Youn Ho | - |
dc.contributor.author | Oh, Jae-Won | - |
dc.contributor.author | Han, Man Yong | - |
dc.contributor.author | Sugihara, George | - |
dc.date.accessioned | 2022-07-08T20:26:47Z | - |
dc.date.available | 2022-07-08T20:26:47Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2019-12 | - |
dc.identifier.issn | 0091-6749 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/146655 | - |
dc.description.abstract | Background: Although the different age groups had differences in sensitivity of asthma exacerbations (AEs) to environmental factors, no comprehensive study has examined the age-stratified effects of environmental factors on AEs. Objective: We sought to examine the short-term effects in age-stratified groups (infants, preschool children, school-aged children, adults, and the elderly) of outdoor environmental factors (air pollutants, weather conditions, aeroallergens, and respiratory viral epidemics) on AEs. Methods: We performed an age-stratified analysis of the short-term effects of 4 groups of outdoor environmental factors on AEs in Seoul Metropolitan City (Korea) from 2008 and 2012. The statistical analysis used a Poisson generalized linear regression model, with a distributed lag nonlinear model for identification of lagged and nonlinear effects and convergent cross-mapping for identification of causal associations. Results: Analysis of the total population (n = 10,233,519) indicated there were 28,824 AE events requiring admission to an emergency department during the study period. Diurnal temperature range had significant effects in pediatric (infants, preschool children, and school-aged children) and elderly (relative risk [RR], 1.056-1.078 and 1.016, respectively) subjects. Tree and weed pollen, human rhinovirus, and influenza virus had significant effects in school-aged children (RR, 1.014, 1.040, 1.042, and 1.038, respectively). Tree pollen and influenza virus had significant effects in adults (RR, 1.026 and 1.044, respectively). Outdoor air pollutants (particulate matter of ≤10 μm in diameter, nitrogen dioxide, ozone, carbon monoxide, and sulfur dioxide) had significant short-term effects in all age groups (except for carbon monoxide and sulfur dioxide in infants). Conclusion: These findings provide a need for the development of tailored strategies to prevent AE events in different age groups. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MOSBY-ELSEVIER | - |
dc.title | Short-term effects of multiple outdoor environmental factors on risk of asthma exacerbations: Age-stratified time-series analysis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Oh, Jae-Won | - |
dc.identifier.doi | 10.1016/j.jaci.2019.08.037 | - |
dc.identifier.scopusid | 2-s2.0-85073815184 | - |
dc.identifier.wosid | 000500694900013 | - |
dc.identifier.bibliographicCitation | JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, v.144, no.6, pp.1542 - 1550.e1 | - |
dc.relation.isPartOf | JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | - |
dc.citation.title | JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | - |
dc.citation.volume | 144 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1542 | - |
dc.citation.endPage | 1550.e1 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Allergy | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalWebOfScienceCategory | Allergy | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.subject.keywordPlus | AIR-POLLUTION | - |
dc.subject.keywordPlus | HOSPITAL ADMISSIONS | - |
dc.subject.keywordPlus | WEATHER | - |
dc.subject.keywordPlus | AEROALLERGENS | - |
dc.subject.keywordPlus | SYMPTOMS | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordAuthor | Asthma exacerbation | - |
dc.subject.keywordAuthor | air pollutant | - |
dc.subject.keywordAuthor | weather condition | - |
dc.subject.keywordAuthor | aeroallergen | - |
dc.subject.keywordAuthor | human rhinovirus | - |
dc.subject.keywordAuthor | influenza virus | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0091674919311856?via%3Dihub | - |
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