Generation of the Icetexane Core by Use of a Heck Strategy: Total Synthesis of Taxamairin B
DC Field | Value | Language |
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dc.contributor.author | Le, Thuy Quynh | - |
dc.contributor.author | Karmakar, Swastik | - |
dc.contributor.author | Lee, Seonmi | - |
dc.contributor.author | Chai, Uiseong | - |
dc.contributor.author | Le, Minh Hoang | - |
dc.contributor.author | Oh, Chang Ho | - |
dc.date.accessioned | 2022-07-09T06:17:03Z | - |
dc.date.available | 2022-07-09T06:17:03Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2019-10 | - |
dc.identifier.issn | 2365-6549 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/147078 | - |
dc.description.abstract | An efficient approach towards the total synthesis of Taxamairin B has been accomplished within 6 steps starting from o-bromobenzylbromide 7 with 45% overall yield. Intramolecular Heck reaction works efficiently to furnish the 6-7-6 fused icetexane scaffold under hydrative condition, which on restructuring affords the key beta,gamma-enedione intermediate. The beta,gamma-double bond has been introduced by the acid catalyzed water assisted elimination of a beta-tertiary alcohol. Later, the beta,gamma-enedione on introduction of requisite unsaturation transforms into Taxamairin B. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.title | Generation of the Icetexane Core by Use of a Heck Strategy: Total Synthesis of Taxamairin B | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Oh, Chang Ho | - |
dc.identifier.doi | 10.1002/slct.201903404 | - |
dc.identifier.scopusid | 2-s2.0-85074765736 | - |
dc.identifier.wosid | 000494027800044 | - |
dc.identifier.bibliographicCitation | CHEMISTRYSELECT, v.4, no.40, pp.11926 - 11929 | - |
dc.relation.isPartOf | CHEMISTRYSELECT | - |
dc.citation.title | CHEMISTRYSELECT | - |
dc.citation.volume | 4 | - |
dc.citation.number | 40 | - |
dc.citation.startPage | 11926 | - |
dc.citation.endPage | 11929 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.subject.keywordPlus | BARBIER-TYPE ALLYLATION | - |
dc.subject.keywordPlus | ASYMMETRIC HECK | - |
dc.subject.keywordPlus | EN-ROUTE | - |
dc.subject.keywordPlus | DITERPENES | - |
dc.subject.keywordPlus | CYCLIZATION | - |
dc.subject.keywordPlus | ALDEHYDES | - |
dc.subject.keywordPlus | CYCLOISOMERIZATION | - |
dc.subject.keywordPlus | DEHYDRATION | - |
dc.subject.keywordAuthor | Taxamairin | - |
dc.subject.keywordAuthor | Icetaxane | - |
dc.subject.keywordAuthor | Heck reaction | - |
dc.subject.keywordAuthor | natural product | - |
dc.subject.keywordAuthor | total synthesis | - |
dc.identifier.url | https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/slct.201903404 | - |
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