Hybrid Nanofiber Scaffold-Based Direct Conversion of Neural Precursor Cells/Dopamine Neurons
DC Field | Value | Language |
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dc.contributor.author | Lim, Mi-Sun | - |
dc.contributor.author | Ko, Seung Hwan | - |
dc.contributor.author | Kim, Min Sung | - |
dc.contributor.author | Lee, Byungjun | - |
dc.contributor.author | Jung, Ho-Sup | - |
dc.contributor.author | Kim, Keesung | - |
dc.contributor.author | Park, Chang-Hwan | - |
dc.date.accessioned | 2022-07-09T12:21:57Z | - |
dc.date.available | 2022-07-09T12:21:57Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2019-07 | - |
dc.identifier.issn | 2005-3606 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/147476 | - |
dc.description.abstract | The concept of cellular reprogramming was developed to generate induced neural precursor cells (iNPCs)/dopaminergic (iDA) neurons using diverse approaches. Here, we investigated the effects of various nanoscale scaffolds (fiber, dot, and line) on iNPC/iDA differentiation by direct reprogramming. The generation and maturation of iDA (microtubule-associated protein 2-positive and tyrosine hydroxylase-positive) and iNPCs (NESTIN-positive and SOX2-positive) increased on fiber and dot scaffolds as compared to that of the flat (control) scaffold. This study demon-strates that nanotopographical environments are suitable for direct differentiation methods and may improve the differentiation efficiency. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC STEM CELL RESEARCH | - |
dc.title | Hybrid Nanofiber Scaffold-Based Direct Conversion of Neural Precursor Cells/Dopamine Neurons | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Chang-Hwan | - |
dc.identifier.doi | 10.15283/ijsc18123 | - |
dc.identifier.scopusid | 2-s2.0-85071453794 | - |
dc.identifier.wosid | 000476654800014 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF STEM CELLS, v.12, no.2, pp.340 - 346 | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF STEM CELLS | - |
dc.citation.title | INTERNATIONAL JOURNAL OF STEM CELLS | - |
dc.citation.volume | 12 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 340 | - |
dc.citation.endPage | 346 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cell Biology | - |
dc.relation.journalWebOfScienceCategory | Cell & Tissue Engineering | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.subject.keywordPlus | MOUSE FIBROBLASTS | - |
dc.subject.keywordPlus | STEM-CELLS | - |
dc.subject.keywordPlus | DIFFERENTIATION | - |
dc.subject.keywordPlus | GENERATION | - |
dc.subject.keywordPlus | SURFACES | - |
dc.subject.keywordPlus | FATE | - |
dc.subject.keywordAuthor | Hybrid nanofiber | - |
dc.subject.keywordAuthor | Direct convcrsion | - |
dc.subject.keywordAuthor | Neural precursor | - |
dc.subject.keywordAuthor | iNPC | - |
dc.identifier.url | https://www.ijstemcell.com/journal/view.html?doi=10.15283/ijsc18123 | - |
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