Shift in Sympathovagal Balance Toward Parasympathetic Predominance Is Associated With Attenuation of Portal Hyperperfusion in Cirrhotic Recipients Undergoing Living Donor Liver Transplant
DC Field | Value | Language |
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dc.contributor.author | Kim, Eseul | - |
dc.contributor.author | Choi, Dontz Lak | - |
dc.contributor.author | Jung, JY | - |
dc.contributor.author | Byun, Sung-Hye | - |
dc.contributor.author | Kim, JD | - |
dc.contributor.author | Jwa, Eun-Kyoung | - |
dc.contributor.author | Kim, TY | - |
dc.contributor.author | Kim, DH | - |
dc.contributor.author | Kim, JH | - |
dc.date.accessioned | 2022-07-09T14:05:42Z | - |
dc.date.available | 2022-07-09T14:05:42Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2019-06 | - |
dc.identifier.issn | 0041-1345 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/147677 | - |
dc.description.abstract | Background. The autonomic innervation to a liver graft remains lost up to 1 year after liver transplant. Therefore, we investigated the effects of recipients' autonomic nervous activity on the extent of portal hyperperfusion of a partial liver graft in the absence of the autonomic innervation. Methods. A total of 31 cirrhotic recipients undergoing right lobe living donor liver transplant were analyzed. Following a 10-minute absence of surgical stimulation after hepatic artery and bile duct reconstruction, the electrocardiogram and blood pressure waveforms were recorded for 5 minutes. Low-frequency (LF) and high-frequency (HF) powers and their ratio (LF/HF) were calculated using fast Fourier transform from the electrocardiogram waveform. A decrease in LF/HF represents a shift in sympathovagal balance toward parasympathetic predominance. Then, portal venous (PVF) and hepatic arterial (HAF) blood flows were measured in mL/min per 100 g of liver weight using spectral Doppler ultrasonography. A decrease in their ratio (PVF/HAF) represents attenuation of portal hyperperfusion. Results. The medians of the PVF and HAF were 349 and 27 mL/min/100 g liver weight with interquartile ranges of 272 to 617 mL/min/100 g liver weight and 22 to 41 mL/min/100 g liver weight, respectively, yielding a median of the PVF/HAF of 13.7 (interquartile range, 8.5-21.3). The median of LF/HF was 0.67 (interquartile range, 0.16-1.45). With a reduction in LF/HF, PVF/HAF decreased according to an S-curve regression model between them (PVF/HAF = e(2.743)+-0.031/Lf/Hf, adjusted R-2 = 0.129, P = 0.027). Conclusion. A shift in sympathovagal balance toward parasympathetic predominance is associated with attenuation of portal hyperperfusion in a partial liver graft. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.title | Shift in Sympathovagal Balance Toward Parasympathetic Predominance Is Associated With Attenuation of Portal Hyperperfusion in Cirrhotic Recipients Undergoing Living Donor Liver Transplant | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Eseul | - |
dc.identifier.doi | 10.1016/j.transproceed.2019.01.117 | - |
dc.identifier.scopusid | 2-s2.0-85066261638 | - |
dc.identifier.wosid | 000471836700045 | - |
dc.identifier.bibliographicCitation | TRANSPLANTATION PROCEEDINGS, v.51, no.5, pp.1511 - 1515 | - |
dc.relation.isPartOf | TRANSPLANTATION PROCEEDINGS | - |
dc.citation.title | TRANSPLANTATION PROCEEDINGS | - |
dc.citation.volume | 51 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 1511 | - |
dc.citation.endPage | 1515 | - |
dc.type.rims | ART | - |
dc.type.docType | Article; Proceedings Paper | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalResearchArea | Transplantation | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.relation.journalWebOfScienceCategory | Transplantation | - |
dc.subject.keywordPlus | HEPATIC BLOOD-FLOW | - |
dc.subject.keywordPlus | ARTERIAL BUFFER RESPONSE | - |
dc.subject.keywordPlus | SPLANCHNIC HEMODYNAMICS | - |
dc.subject.keywordPlus | HEART-RATE | - |
dc.subject.keywordPlus | PRESSURE | - |
dc.subject.keywordPlus | NERVES | - |
dc.subject.keywordPlus | STIMULATION | - |
dc.subject.keywordPlus | DESFLURANE | - |
dc.subject.keywordPlus | OCCLUSION | - |
dc.subject.keywordPlus | GRAFT | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0041134518314830?via%3Dihub | - |
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