The clinical value of 4-hour delayed-enhanced 3D-FLAIR MR images in sudden hearing loss
DC Field | Value | Language |
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dc.contributor.author | Byun, Ha young | - |
dc.contributor.author | Chung, Jae Ho | - |
dc.contributor.author | Lee, Seung Hwan | - |
dc.contributor.author | Park, Chul Won | - |
dc.contributor.author | Park, Dong Woo | - |
dc.contributor.author | Kin, Tae Yoon | - |
dc.date.accessioned | 2022-07-09T18:06:39Z | - |
dc.date.available | 2022-07-09T18:06:39Z | - |
dc.date.created | 2021-05-11 | - |
dc.date.issued | 2019-05 | - |
dc.identifier.issn | 1749-4478 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/147916 | - |
dc.description.abstract | ObjectiveThe aim of this study was to investigate the clinical significance of 4-hour delayed-enhanced 3.0 Tesla (3T) 3D-fluid-attenuated inversion recovery (FLAIR) MR imaging in sudden sensorineural hearing loss (SSNHL). Study designCase series with comparisons. SettingTertiary referral centre. ParticipantsEighty-seven idiopathic SSNHL patients were enrolled between January 2015 and December 2016 and received high dose steroid therapy and intratympanic steroid injections as salvage treatment. InterventionPre-contrast, 10-minute and 4-hour delayed-enhanced 3D-FLAIR MR images were obtained using double-dose IV gadolinium. Main outcome measuresThe results of treatment were evaluated according to Siegel's criteria 3months after the start of treatment. Where possible lesion-side laterality of the inner ear was identified based on the MR images, the associations between MR findings and other clinical parameters were analysed, and the relationships between hearing recovery and MR image findings were assessed. ResultsLesion-side laterality was identified on MRI in 52 (59.7%), 18 (20.1%) and 8 (9.2%) patients, based on 4-hour delayed, 10-minute delayed, and pre-contrast images, respectively. The hearing recovery rate was significantly lower in the patients with lesion-side laterality on 4-hour delayed images (P<0.001). In a multivariate analysis, lesion-side laterality on 4-hour delayed images was associated with poor prognosis (OR=5.6) after adjusting other prognostic factors including initial hearing level, lesion-side laterality on 10-min delayed images and presence of vertigo. In addition, as the extent of enhancement in the inner ear increased the probability of hearing recover decreased (P=0.001). ConclusionsContrast enhancement of inner ear structures can be seen on 4-hour delayed-enhanced 3T 3D-FLAIR MR images in idiopathic SSNHL. Asymmetric lesion-side enhancement of the inner ear may be associated with a poor prognosis. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.title | The clinical value of 4-hour delayed-enhanced 3D-FLAIR MR images in sudden hearing loss | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Byun, Ha young | - |
dc.contributor.affiliatedAuthor | Chung, Jae Ho | - |
dc.contributor.affiliatedAuthor | Lee, Seung Hwan | - |
dc.contributor.affiliatedAuthor | Park, Dong Woo | - |
dc.identifier.doi | 10.1111/coa.13305 | - |
dc.identifier.scopusid | 2-s2.0-85061991082 | - |
dc.identifier.wosid | 000476843600018 | - |
dc.identifier.bibliographicCitation | CLINICAL OTOLARYNGOLOGY, v.44, no.3, pp.336 - 342 | - |
dc.relation.isPartOf | CLINICAL OTOLARYNGOLOGY | - |
dc.citation.title | CLINICAL OTOLARYNGOLOGY | - |
dc.citation.volume | 44 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 336 | - |
dc.citation.endPage | 342 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Otorhinolaryngology | - |
dc.relation.journalWebOfScienceCategory | Otorhinolaryngology | - |
dc.subject.keywordPlus | PROGNOSTIC-FACTORS | - |
dc.subject.keywordPlus | RECOVERY | - |
dc.subject.keywordPlus | SEQUENCE | - |
dc.subject.keywordAuthor | fluid-attenuated inversion recovery | - |
dc.subject.keywordAuthor | hearing loss | - |
dc.subject.keywordAuthor | magnetic resonance imaging | - |
dc.subject.keywordAuthor | sudden sensorineural hearing loss | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1111/coa.13305 | - |
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