Changes in the optic nerve head induced by horizontal eye movements
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Won June | - |
dc.contributor.author | Kim, Yu Jeong | - |
dc.contributor.author | Kim, Ji Hong | - |
dc.contributor.author | Hwang, Sunjin | - |
dc.contributor.author | Shin, Seung Hak | - |
dc.contributor.author | Lim, Han Woong | - |
dc.date.accessioned | 2022-07-11T12:00:30Z | - |
dc.date.available | 2022-07-11T12:00:30Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2018-09 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/149441 | - |
dc.description.abstract | Purpose To investigate the effect of eye movement on the optic nerve head (ONH) using swept-source optical coherence tomography (SS-OCT), and to measure the degree of ONH changes. Methods We enrolled 52 healthy subjects, 20 to 40 years of age, and performed a prospective observational study. Both ONH and macula were imaged simultaneously using wide volume scan of the SS-OCT in the primary and different gaze positions. Horizontal eye movements were used to obtain OCT images in abducted and adducted eyeball positions. Multilateral 3-dimensional registration was used to process and analyze the images to measure the degree of ONH changes. Results The mean axial length (AXL) was 25.73 ± 1.42mm and the mean spherical equivalents was -4.49 ± 2.94 D (The proportion of high myopia was 39.4%). Significant morphologic changes were observed in the ONH during both abduction and adduction. In abduction, the overall ONH tissues were elevated, and the mean area of elevation was 115,134 ± 9,424 μm2 (p<0.001). In adduction, the mean areas from two perspectives, which were nasal or temporal, and peripapillary tissues or optic nerve cupping were 95,277 ± 73,846 μm2, 34,450 ± 44,948 μm2, -108,652 ± 91,246 μm2, and -30,581 ± 46,249 μm2, respectively. Elevation in abduction (overall, nasal cup segment, and temporal cup segment; R = 0.204, 0.195 and 0.225, p = 0.038, 0.047 and 0.021, respectively) and elevation of nasal peripapillary segments in adduction were positively correlated with AXL (R = 0.346, p<0.001). Conclusion We found significant morphologic changes in the ONH in both abduction and adduction and these changes were associated with AXL. Considering these morphologic changes as physical properties, it allows a better understanding of the biomechanical characteristics of the ONH. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | PUBLIC LIBRARY SCIENCE | - |
dc.title | Changes in the optic nerve head induced by horizontal eye movements | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Won June | - |
dc.contributor.affiliatedAuthor | Lim, Han Woong | - |
dc.identifier.doi | 10.1371/journal.pone.0204069 | - |
dc.identifier.scopusid | 2-s2.0-85053622109 | - |
dc.identifier.wosid | 000444918300041 | - |
dc.identifier.bibliographicCitation | PLOS ONE, v.13, no.9, pp.1 - 13 | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.citation.title | PLOS ONE | - |
dc.citation.volume | 13 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 13 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | COHERENCE TOMOGRAPHY | - |
dc.subject.keywordPlus | MULTIPLE-SCLEROSIS | - |
dc.subject.keywordPlus | AXON DIAMETER | - |
dc.subject.keywordPlus | DUCTION | - |
dc.subject.keywordPlus | DEFORMATIONS | - |
dc.subject.keywordPlus | SHEATH | - |
dc.subject.keywordPlus | LAYER | - |
dc.subject.keywordPlus | GAZE | - |
dc.identifier.url | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0204069 | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.