Interleukin-6-Mediated Induced Pluripotent Stem Cell (iPSC)-Derived Neural Differentiation
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Sulistio, Yanuar Alan | - |
dc.contributor.author | Lee, Han Kyu | - |
dc.contributor.author | Jung, Sung Jun | - |
dc.contributor.author | Heese, Klaus | - |
dc.date.accessioned | 2022-07-12T00:51:10Z | - |
dc.date.available | 2022-07-12T00:51:10Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2018-04 | - |
dc.identifier.issn | 0893-7648 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/150276 | - |
dc.description.abstract | In an aging society with an increasing threat to higher brain cognitive functions due to dementia, it becomes imperative to identify new molecular remedies for supporting adult neurogenesis. Interleukin-6 (IL-6) is a promising cytokine that can support neurogenesis under conditions of neurodegeneration, and neuron replacement is eventually possible due to its agonistic acting soluble receptor sIL-6R. Here, we report that activation of the IL-6-signal transducer and activator of transcription 3 (STAT3) axis is neurogenic and has potential therapeutic applications for the treatment of neurodegenerative diseases such as Parkinson's disease (PD). | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | HUMANA PRESS INC | - |
dc.title | Interleukin-6-Mediated Induced Pluripotent Stem Cell (iPSC)-Derived Neural Differentiation | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jung, Sung Jun | - |
dc.contributor.affiliatedAuthor | Heese, Klaus | - |
dc.identifier.doi | 10.1007/s12035-017-0594-3 | - |
dc.identifier.scopusid | 2-s2.0-85019217160 | - |
dc.identifier.wosid | 000427097500060 | - |
dc.identifier.bibliographicCitation | MOLECULAR NEUROBIOLOGY, v.55, no.4, pp.3513 - 3522 | - |
dc.relation.isPartOf | MOLECULAR NEUROBIOLOGY | - |
dc.citation.title | MOLECULAR NEUROBIOLOGY | - |
dc.citation.volume | 55 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 3513 | - |
dc.citation.endPage | 3522 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.subject.keywordPlus | PROMOTES NEURONAL DIFFERENTIATION | - |
dc.subject.keywordPlus | LEUKEMIA INHIBITORY FACTOR | - |
dc.subject.keywordPlus | CENTRAL-NERVOUS-SYSTEM | - |
dc.subject.keywordPlus | PC12 CELLS | - |
dc.subject.keywordPlus | DOPAMINERGIC-NEURONS | - |
dc.subject.keywordPlus | NEURITE OUTGROWTH | - |
dc.subject.keywordPlus | PROGENITOR CELLS | - |
dc.subject.keywordPlus | PARKINSONS-DISEASE | - |
dc.subject.keywordPlus | ASTROCYTIC DIFFERENTIATION | - |
dc.subject.keywordPlus | FUNCTIONAL RECOVERY | - |
dc.subject.keywordAuthor | BDNF | - |
dc.subject.keywordAuthor | Brain | - |
dc.subject.keywordAuthor | Interleukin-6 | - |
dc.subject.keywordAuthor | Neuron | - |
dc.subject.keywordAuthor | Neurotrophin | - |
dc.subject.keywordAuthor | STAT3 | - |
dc.identifier.url | https://link.springer.com/article/10.1007/s12035-017-0594-3 | - |
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